CAS 434-03-7

Ethisterone

Description:

Ethisterone, also known as 17α-ethynyltestosterone, is a synthetic steroid hormone that belongs to the class of progestins. It is characterized by its structural similarity to testosterone, featuring an ethynyl group at the 17α position, which enhances its oral bioavailability and potency. Ethisterone is primarily used in hormonal therapies, including contraceptives and treatments for menstrual disorders. Its mechanism of action involves binding to progesterone receptors, thereby influencing the menstrual cycle and maintaining pregnancy. The substance is typically administered in oral form and is known for its ability to regulate ovulation and menstrual cycles. Ethisterone exhibits a relatively long half-life, allowing for sustained therapeutic effects. Additionally, it may have androgenic properties, which can lead to side effects such as weight gain, mood changes, and alterations in libido. As with other synthetic hormones, careful monitoring is essential to mitigate potential adverse effects and ensure effective treatment outcomes.

Formula: C₂₁H₂₈O₂

InChI: InChI=1S/C21H28O2/c1-4-21(23)12-9-18-16-6-5-14-13-15(22)7-10-19(14,2)17(16)8-11-20(18,21)3/h1,13,16-18,23H,5-12H2,2-3H3/t16-,17+,18+,19+,20+,21+/m1/s1

InChI key: InChIKey=CHNXZKVNWQUJIB-CEGNMAFCSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)CC4)(CC1)[H])[H])(CC[C@]2(C#C)O)[H]

Synonyms:

• (17Alpha)-17-Hydroxypregn-4-En-20-Yn-3-One
• (17α)-17-Hydroxypregn-4-en-20-yn-3-one
• (8Xi,9Xi,10Xi,13Xi,14Xi,17Alpha)-17-Hydroxypregn-4-En-20-Yn-3-One
• (8Xi,9Xi,14Xi,17Alpha)-17-Hydroxypregn-4-En-20-Yn-3-One
• 17-Alpha-Ethynyltestosterone
• 17-Ethynyl-17-hydroxy-3-ketoandrostene-4
• 17-Ethynyl-17β-hydroxyandrost-4-en-3-one
• 17-Hydroxy-17α-pregn-4-en-20-yn-3-one
• 17-Hydroxypregn-4-En-20-Yn-3-One
• 17A-Ethynyl Testosterone
• 17A-Ethynyl-17B-Hydroxy-4-Androsten-3-One
• 17α-Ethynyl-17-hydroxyandrost-4-en-3-one
• 17α-Ethynyl-4-androsten-17β-ol-3-one
• 17α-Ethynyltestosterone
• 17α-Pregn-4-en-20-yn-3-one, 17-hydroxy-
• 17β-Hydroxy-17α-ethynylandrost-4-en-3-one
• 17β-Hydroxy-17α-pregn-4-en-20-yn-3-one
• 4-Androsten-17α-ethinyl-17β-ol-3-one
• Aethisteron
• Anhydrohydroxyprogesterone
• Anhydroxyprogesterone
• Colutoid
• Ethinone
• Ethinyltestosterone
• Ethisterone,98%
• Ethynyl Testosterone
• Ethynyltestosterone
• Gestoral
• Lucorteum Oral
• Lutidon Oral
• Lutocyclin-Linguetten
• Lutocyclol
• Lutocylol
• NSC 9565
• Nalutoral
• Nugestoral
• Ora-Lutin
• Pranone
• Pregn-4-en-17β-ol-3-on-20-yne
• Pregn-4-en-20-yn-3-one, 17-hydroxy-, (17α)-
• Pregneninolone
• Pregnin
• Primolut C
• Prodoxan
• Prodroxan
• Produxan
• Progestab
• Progestin P
• Progestolets
• Progestoral
• Prolutol
• Proluton C
• Prone
• Syngestrotabs
• Testosterone, 17-ethynyl-

Ethisterone

CAS: 434-03-7

Formula: C₂₁H₂₈O₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 312.45

Ref: 3B-E0040

Ethisterone, 98%

CAS: 434-03-7

It was the first orally-active progestin. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a

Formula: C₂₁H₂₈O₂

Purity: 98%

Molecular weight: 312.45

Ref: 02-J63580

Ethisterone

CAS: 434-03-7

Estrogens and progestins

Formula: C₂₁H₂₈O₂

Color and Shape: White Powder

Molecular weight: 312.20893

Ref: 45-1261117

Ethisterone

CAS: 434-03-7

Ethisterone (17α-Ethynyltestosterone) is a progestogen hormone.

Formula: C₂₁H₂₈O₂

Purity: 97.96% - 99.50%

Color and Shape: White Solid

Molecular weight: 312.45

Ref: TM-T0301

Ethisterone

CAS: 434-03-7

Formula: C₂₁H₂₈O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 312.4458

Ref: IN-DA003PYT

Ethisterone

CAS: 434-03-7

Formula: C₂₁H₂₈O₂

Purity: (HPLC) ≥ 98.0% (dried basis)

Color and Shape: White to off-white crystalline powder

Molecular weight: 312.45

Ref: 7W-GP7068

Ethisterone

CAS: 434-03-7

Ethisterone

Formula: C₂₁H₂₈O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 312.45

Ref: 54-OR1029070

Ethisterone

CAS: 434-03-7

Ethisterone

Formula: C₂₁H₂₈O₂

Purity: ≥95%

Molecular weight: 312.45

Ref: 54-BUP14689

Ethisterone

Controlled Product

CAS: 434-03-7

Formula: C₂₁H₂₈O₂

Color and Shape: Neat

Molecular weight: 312.45

Ref: 04-C13283000

Ethisterone

Controlled Product

CAS: 434-03-7

Formula: C₂₁H₂₈O₂

Color and Shape: Neat

Molecular weight: 312.45

Ref: 86-MM0967.00

Ethisterone

Controlled Product

CAS: 434-03-7

Color and Shape: Neat

Ref: 61-FOR0967.00

Ethisterone

Controlled Product

CAS: 434-03-7

Applications Synthetic progestogen; metabolite of Danazol; intermediate in the synthesis of Spironolactone.
References Chung, B., et al.: J. Anal. Toxicol., 14, 91 (1990), Schanzer, W., et al.: J. Steroid. Biochem. Mol. Biol., 57, 363 (1996), Chan, G., et al.: Am. J. Hematol., 71, 166 (2002), Szegvari, D., et al.: Anal. Bioanal. Chem., 375, 713 (2003)

Formula: C₂₁H₂₈O₂

Color and Shape: Neat

Molecular weight: 312.45

Ref: TR-E890445

Ethisterone

Controlled Product

CAS: 434-03-7

Progesterone receptor agonist

Formula: C₂₁H₂₈O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 312.45 g/mol

Ref: 3D-FE22865

Ethisterone-13C2 (>90%)

Controlled Product

CAS: 434-03-7

Applications A labelled synthetic progestogen; metabolite of Danazol; intermediate in the synthesis of Spironolactone.
References Chung, B., et al.: J. Anal. Toxicol., 14, 91 (1990), Schanzer, W., et al.: J. Steroid. Biochem. Mol. Biol., 57, 363 (1996), Chan, G., et al.: Am. J. Hematol., 71, 166 (2002), Szegvari, D., et al.: Anal. Bioanal. Chem., 375, 713 (2003)

Formula: C₁₉₁₃C₂H₂₈O₂

Purity: >90%

Color and Shape: Neat

Molecular weight: 314.43

Ref: TR-E890447

Ethisterone

CAS: 434-03-7

Formula: C₂₁H₂₈O₂

Molecular weight: 312.45

Ref: ST-EA-CP-E292000