CAS 4359-87-9

2,4,6-Trichloro-5-nitropyrimidine

Description:

2,4,6-Trichloro-5-nitropyrimidine is a heterocyclic organic compound characterized by a pyrimidine ring substituted with three chlorine atoms and one nitro group. Its molecular structure features a six-membered aromatic ring containing two nitrogen atoms at positions 1 and 3, which contributes to its basicity and reactivity. The presence of the nitro group at the 5-position enhances its electrophilic character, making it a useful intermediate in various chemical syntheses, particularly in the pharmaceutical and agrochemical industries. This compound is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. Due to the presence of chlorine substituents, it can participate in nucleophilic substitution reactions. Safety precautions are necessary when handling this compound, as it may pose health risks, including potential toxicity and environmental hazards. Proper storage and disposal methods should be followed to mitigate any risks associated with its use.

Formula: C₄Cl₃N₃O₂

InChI: InChI=1/C4Cl3N3O2/c5-2-1(10(11)12)3(6)9-4(7)8-2

SMILES: c1(c(Cl)nc(Cl)nc1Cl)N(=O)=O

Synonyms:

• Pyrimidine, 2,4,6-Trichloro-5-Nitro-

2,4,6-Trichloro-5-nitropyrimidine

CAS: 4359-87-9

Formula: C₄Cl₃N₃O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 228.4207

Ref: IN-DA0032YI

5-Nitro-2,4,6-trichloropyrimidine

CAS: 4359-87-9

5-Nitro-2,4,6-trichloropyrimidine

Formula: C₄Cl₃N₃O₂

Purity: 98%

Color and Shape: light yellow solid

Molecular weight: 228.42g/mol

Ref: 54-OR313061

2,4,6-Trichloro-5-nitropyrimidine

CAS: 4359-87-9

Formula: C₄Cl₃N₃O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 228.41

Ref: 10-F047213

2,4,6-Trichloro-5-nitropyrimidine

CAS: 4359-87-9

2,4,6-Trichloro-5-nitropyrimidine is a purine derivative that inhibits the cell proliferation of cancer cells. It has been shown to inhibit the activity of kinases and to induce apoptosis in human cancer cells in vitro. This drug also has antiproliferative potential against erythrocytes and is being investigated as a treatment for renal disease. 2,4,6-Trichloro-5-nitropyrimidine shows inhibitory effects on the phosphorylation of roscovitine by ATP and may be used to treat patients with glomerulonephritis. 2,4,6-Trichloro-5-nitropyrimidine can be synthesized from 2,4,6-trichloropyrimidinethiol and nitric acid according to the following equation: CClNO + HNO → CClNOH + NO 2 Cl + 3 HNO

Formula: C₄Cl₃N₃O₂

Purity: Min. 97 Area-%

Molecular weight: 228.42 g/mol

Ref: 3D-FT154562