CAS 439687-69-1

(2S,4R)-1-[(3R)-5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide

Description:

The chemical substance with the name "(2S,4R)-1-[(3R)-5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide" and CAS number "439687-69-1" is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups such as sulfonamides, amides, and hydroxyl groups. This compound features a chiral center, indicated by the stereochemical descriptors (2S,4R) and (3R), which suggests that it may exhibit specific biological activity or pharmacological properties due to its stereochemistry. The presence of chloro and methoxy substituents on the aromatic rings contributes to its potential reactivity and interaction with biological targets. Additionally, the indole moiety is often associated with various biological activities, making this compound of interest in medicinal chemistry. Its solubility, stability, and reactivity would depend on the specific conditions, including pH and solvent, which are critical for its application in research or therapeutic contexts.

Formula: C₃₀H₃₂ClN₃O₈S

InChI: InChI=1S/C30H32ClN3O8S/c1-32(2)28(36)24-15-19(35)17-33(24)30(21-8-6-7-9-25(21)41-4)22-14-18(31)10-12-23(22)34(29(30)37)43(38,39)27-13-11-20(40-3)16-26(27)42-5/h6-14,16,19,24,35H,15,17H2,1-5H3/t19-,24+,30+/m1/s1

InChI key: InChIKey=NJXZWIIMWNEOGJ-WEWKHQNJSA-N

SMILES: O=C1[C@](C=2C(N1S(=O)(=O)C3=C(OC)C=C(OC)C=C3)=CC=C(Cl)C2)(N4[C@H](C(N(C)C)=O)C[C@@H](O)C4)C5=C(OC)C=CC=C5

Synonyms:

• SSR 149415
• 2-Pyrrolidinecarboxamide, 1-[(3R)-5-chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-, (2S,4R)-
• (2S,4R)-1-[(3R)-5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide
• Nelivaptan
• SSR 149415 - Nelivaptan
• (2S,4R)-1-[(R)-5-CHLORO-1-(2,4-DIMETHOXY-BENZENESULFONYL)-3-(2-METHOXY-PHENYL)-2-OXO-2,3-DIHYDRO-1H-INDOL-3-YL]-4-HYDROXY-PYRROLIDINE-2-CARBOXYLIC ACID DIMETHYLAMIDE
• (2S,4R)-1-[(3R)-5-chloro-1-(2,4-dimethoxyphenyl)sulfonyl-3-(2-methoxyphenyl)-2-oxoindol-3-yl]-4-hydroxy-N,N-dimethylpyrrolidine-2-carboxamide
• Nelivaptan(SSR-149,415)

Nelivaptan

CAS: 439687-69-1

Nelivaptan (SR 149415) is a vasopressin V1b receptor antagonist that can eliminate CHS-induced GE damage.Cost-effective and quality-assured.

Formula: C₃₀H₃₂ClN₃O₈S

Purity: 98.46% - 99.89%

Color and Shape: Solid

Molecular weight: 630.11

Ref: TM-T28153

Nelivaptan

CAS: 439687-69-1

Nelivaptan

Purity: ≥95%

Molecular weight: 630.11g/mol

Ref: 54-BUP07358

SSR 149415

Controlled Product

CAS: 439687-69-1

Formula: C₃₀H₃₂ClN₃O₈S

Color and Shape: Neat

Molecular weight: 630.108

Ref: TR-S684528

SSR 149415

CAS: 439687-69-1

SSR 149415 is an orally active small molecule that inhibits the activity of receptor tyrosine kinases (RTKs) and can be used to treat autoimmune diseases. SSR 149415 has been shown to inhibit the expression of osteogenic genes in cells. It has also been shown to inhibit the proliferation of prostate cancer cells by binding to the RTKs and inhibiting their downstream signaling pathways. The molecule has been shown to have a high affinity for asymmetric synthesis, which makes it more stable than other molecules. SSR 149415 has been found to bind specifically with polymorphic regions on a number of different proteins, which may make it useful for diagnostic purposes.
SSR 149415 was shown to block dopamine release from striatal neurons in cell culture studies, indicating that this drug may be useful in treating Parkinson’s disease.

Formula: C₃₀H₃₂ClN₃O₈S

Purity: Min. 95%

Molecular weight: 630.1 g/mol

Ref: 3D-PSA68769