CAS 439687-69-1

(2S,4R)-1-[(3R)-5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide

Formula: C₃₀H₃₂ClN₃O₈S

InChI: InChI=1S/C30H32ClN3O8S/c1-32(2)28(36)24-15-19(35)17-33(24)30(21-8-6-7-9-25(21)41-4)22-14-18(31)10-12-23(22)34(29(30)37)43(38,39)27-13-11-20(40-3)16-26(27)42-5/h6-14,16,19,24,35H,15,17H2,1-5H3/t19-,24+,30+/m1/s1

InChI key: InChIKey=NJXZWIIMWNEOGJ-WEWKHQNJSA-N

SMILES: O=C1[C@](C=2C(N1S(=O)(=O)C3=C(OC)C=C(OC)C=C3)=CC=C(Cl)C2)(N4[C@H](C(N(C)C)=O)C[C@@H](O)C4)C5=C(OC)C=CC=C5

Synonyms:

• SSR 149415
• 2-Pyrrolidinecarboxamide, 1-[(3R)-5-chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-, (2S,4R)-
• (2S,4R)-1-[(3R)-5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide
• Nelivaptan
• SSR 149415 - Nelivaptan
• (2S,4R)-1-[(R)-5-CHLORO-1-(2,4-DIMETHOXY-BENZENESULFONYL)-3-(2-METHOXY-PHENYL)-2-OXO-2,3-DIHYDRO-1H-INDOL-3-YL]-4-HYDROXY-PYRROLIDINE-2-CARBOXYLIC ACID DIMETHYLAMIDE
• (2S,4R)-1-[(3R)-5-chloro-1-(2,4-dimethoxyphenyl)sulfonyl-3-(2-methoxyphenyl)-2-oxoindol-3-yl]-4-hydroxy-N,N-dimethylpyrrolidine-2-carboxamide
• Nelivaptan(SSR-149,415)

Nelivaptan

CAS: 439687-69-1

Nelivaptan (SR 149415) is a vasopressin V1b receptor antagonist that can eliminate CHS-induced GE damage.Cost-effective and quality-assured.

Formula: C₃₀H₃₂ClN₃O₈S

Purity: 99.46% - 99.89%

Color and Shape: Solid

Molecular weight: 630.108

Ref: TM-T28153

Nelivaptan

CAS: 439687-69-1

Nelivaptan

Formula: C₃₀H₃₂ClN₃O₈S

Purity: 99.5%

Molecular weight: 630.11

Ref: 54-BUP07358

Nelivaptan

CAS: 439687-69-1

Purity: 98%

Ref: IN-DA00DGZI

Nelivaptan

CAS: 439687-69-1

(2S,4R)-1-((R)-5-Chloro-1-((2,4-dimethoxyphenyl)sulfonyl)-3-(2-methoxyphenyl)-2-oxoindolin-3-yl)-4-hydroxy-N,N-dimethylpyrrolidine-2-carboxamide

Formula: C₃₀H₃₂ClN₃O₈S

Purity: 98%

Molecular weight: 630.11

Ref: IN-DG01302331

SSR 149415

Controlled Product

CAS: 439687-69-1

Formula: C₃₀H₃₂ClN₃O₈S

Color and Shape: Neat

Molecular weight: 630.108

Ref: TR-S684528

SSR 149415

CAS: 439687-69-1

SSR 149415 is an orally active small molecule that inhibits the activity of receptor tyrosine kinases (RTKs) and can be used to treat autoimmune diseases. SSR 149415 has been shown to inhibit the expression of osteogenic genes in cells. It has also been shown to inhibit the proliferation of prostate cancer cells by binding to the RTKs and inhibiting their downstream signaling pathways. The molecule has been shown to have a high affinity for asymmetric synthesis, which makes it more stable than other molecules. SSR 149415 has been found to bind specifically with polymorphic regions on a number of different proteins, which may make it useful for diagnostic purposes.
SSR 149415 was shown to block dopamine release from striatal neurons in cell culture studies, indicating that this drug may be useful in treating Parkinson’s disease.

Formula: C₃₀H₃₂ClN₃O₈S

Purity: Min. 95%

Molecular weight: 630.1 g/mol

Ref: 3D-PSA68769