CAS 443678-71-5

5,6-Dichloropurine-1-(2,3,5-tri-O-acetyl-b-D-ribofuanosyl)-1H-benzimidazole

CAS: 443678-71-5

Ref: 7W-GN2941

5,6-Dichloropurine-1-(2,3,5-tri-O-acetyl-β-D-ribofuanosyl)-1H-benzimidazole

Controlled Product

CAS: 443678-71-5

Applications A protected inhibitor of RNA synthesis (causes premature termination of transcription).
References Braedlye, J. and Sporns, O.: Brain Res., 815, 140 (1999), Ljungman, M., et al.: Oncogene, 18, 583 (1999), Roele, R.H., et al.: Oncogene, 18, 5765 (1999)

Formula: C₁₈H₁₈Cl₂N₂O₇

Color and Shape: Neat

Molecular weight: 445.25

Ref: TR-D435935

5,6-Dichloropurine-1-(2,3,5-tri-O-acetyl-b-D-ribofuanosyl)-1H-benzimidazole

CAS: 443678-71-5

5,6-Dichloropurine-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-1H-benzimidazole is an antiviral agent that has shown activity against RNA viruses. It is a modified nucleoside monophosphate that inhibits the synthesis of viral ribonucleic acid (RNA) by binding to the enzyme RNA polymerase. 5,6-Dichloropurine is also a novel anticancer drug with antiangiogenic and antitumor properties. The compound was found to be effective in inhibiting the growth of human cancer cells in vitro. 5,6-Dichloropurine has been shown to inhibit protein synthesis through inhibition of diphosphate activation of ribonucleotide reductase and DNA polymerase. This product is synthesized using high purity and high quality reagents with excellent yield. It can be used as an

Formula: C₁₈H₁₈Cl₂N₂O₇

Purity: Min. 95%

Molecular weight: 445.25 g/mol

Ref: 3D-ND16534