CAS 443797-96-4

4-[[5-Amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino]benzenesulfonamide

Description:

4-[[5-Amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino]benzenesulfonamide, with CAS number 443797-96-4, is a chemical compound characterized by its complex structure, which includes a sulfonamide group and a triazole moiety. This compound typically exhibits properties such as high solubility in polar solvents and potential bioactivity, making it of interest in pharmaceutical research, particularly in the development of antimicrobial or antifungal agents. The presence of the difluorobenzoyl group may enhance its lipophilicity and biological activity. Additionally, the amino and sulfonamide functionalities contribute to its reactivity and potential interactions with biological targets. The compound's molecular structure suggests it may participate in hydrogen bonding and other intermolecular interactions, which are crucial for its efficacy in biological systems. Overall, this substance represents a class of compounds that may have significant applications in medicinal chemistry and drug development.

Formula: C₁₅H₁₂F₂N₆O₃S

Synonyms:

• Jnj-7706621

4-[[5-Amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino]benzenesulfonamide

CAS: 443797-96-4

Formula: C₁₅H₁₂F₂N₆O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 394.3560

Ref: IN-DA0037G8

JNJ-7706621

CAS: 443797-96-4

JNJ-7706621

Purity: ≥98%

Molecular weight: 394.36g/mol

Ref: 54-BUP12504

JNJ-7706621

CAS: 443797-96-4

JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.

Formula: C₁₅H₁₂F₂N₆O₃S

Purity: 99.1% - 99.85%

Color and Shape: Solid

Molecular weight: 394.36

Ref: TM-T6126

JNJ-7706621

CAS: 443797-96-4

Ref: 7W-GW4079

4-((5-Amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl)amino)benzenesulfonamide

CAS: 443797-96-4

Formula: C₁₅H₁₂F₂N₆O₃S

Purity: 99%

Molecular weight: 394.36

Ref: 10-F239290

JNJ-7706621

Controlled Product

CAS: 443797-96-4

Applications JNJ-770662 is a broad spectrum inhibitor of cyclin-dependent kinases and aurora kinases including CDK1/Cyclin B, CDK2/Cyclin A, CDK2/Cyclin E, Aurora-A and Aurora-B. JNJ-770662 has been shown to induce growth suppression and mitotic defects, these results suggest that JNJ-7706621 could be useful for cell cycle analysis and therapy of various cancers, including Ewing's sarcoma.
References Matsuhashi, A. et al.: Curr. Cancer Drug Tar., 12, 625 (2012); Emanue,l S. et al.: Cancer Res., 65, 9038 (2005); Seamon, J.A. et al.: Mol. Cancer Ther., 5, 2459 (2006);

Formula: C₁₅H₁₂F₂N₆O₃S

Color and Shape: Neat

Molecular weight: 394.356

Ref: TR-J211310