CAS 444606-18-2
:Dilmapimod
Description:
Dilmapimod, also known by its chemical name, is a small molecule inhibitor primarily targeting p38 mitogen-activated protein kinase (MAPK). This compound is characterized by its role in modulating inflammatory responses and has been investigated for its potential therapeutic applications in various diseases, including autoimmune disorders and cancer. Dilmapimod exhibits a specific mechanism of action by inhibiting the phosphorylation of downstream targets involved in inflammatory signaling pathways. Its chemical structure includes functional groups that contribute to its binding affinity and selectivity for the p38 MAPK enzyme. The substance is typically administered in a pharmaceutical context, and its efficacy and safety profile have been evaluated in clinical trials. As with many investigational drugs, the pharmacokinetics, metabolism, and potential side effects are critical aspects of its development and use. Overall, Dilmapimod represents a significant focus in the field of medicinal chemistry, particularly in the context of developing targeted therapies for inflammatory conditions.
Formula:C23H19F3N4O3
InChI:InChI=1S/C23H19F3N4O3/c1-12-9-13(24)5-6-15(12)20-16-7-8-19(33)30(21-17(25)3-2-4-18(21)26)22(16)29-23(28-20)27-14(10-31)11-32/h2-9,14,31-32H,10-11H2,1H3,(H,27,28,29)
InChI key:InChIKey=ORVNHOYNEHYKJG-UHFFFAOYSA-N
SMILES:O=C1N(C=2C(=C(N=C(NC(CO)CO)N2)C3=C(C)C=C(F)C=C3)C=C1)C4=C(F)C=CC=C4F
Synonyms:- 8-(2,6-Difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-[(2-hydroxy-1-hydroxymethylethyl)amino]-8H-pyrido[2,3-d]pyrimidin-7-one
- Pyrido[2,3-d]pyrimidin-7(8H)-one, 8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-
- Dilmapimod
- 8-(2,6-Difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one
- SB 681323
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Found 5 products.
Dilmapimod
CAS:Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.Formula:C23H19F3N4O3Purity:97.53%Color and Shape:White SolidMolecular weight:456.428-(2,6-Difluorophenyl)-2-((1,3-Dihydroxypropan-2-Yl)Amino)-4-(4-Fluoro-2-Methylphenyl)Pyrido[2,3-D]Pyrimidin-7(8H)-One
CAS:8-(2,6-Difluorophenyl)-2-((1,3-Dihydroxypropan-2-Yl)Amino)-4-(4-Fluoro-2-Methylphenyl)Pyrido[2,3-D]Pyrimidin-7(8H)-OneFormula:C23H19F3N4O3Purity:99%Molecular weight:456.42Dilmapimod
CAS:8-(2,6-Difluorophenyl)-2-((1,3-dihydroxypropan-2-yl)amino)-4-(4-fluoro-2-methylphenyl)pyrido[2,3-d]pyrimidin-7(8H)-oneFormula:C23H19F3N4O3Purity:99%Molecular weight:456.42
