CAS 444912-75-8

1-[(N-Methyl-2-piperidinyl)methyl]-3-(2-iodobenzoyl)-1H-indole

Description:

1-[(N-Methyl-2-piperidinyl)methyl]-3-(2-iodobenzoyl)-1H-indole is a chemical compound characterized by its complex structure, which includes an indole core, a piperidine ring, and an iodobenzoyl group. The presence of the indole moiety suggests potential biological activity, as indoles are often found in various natural products and pharmaceuticals. The N-methyl-2-piperidinyl group contributes to the compound's lipophilicity, potentially enhancing its ability to cross biological membranes. The iodobenzoyl substituent may impart unique electronic properties and influence the compound's reactivity and interaction with biological targets. This compound is likely to be of interest in medicinal chemistry, particularly in the development of new therapeutic agents, due to its structural features that may interact with specific receptors or enzymes. Additionally, the iodine atom can serve as a useful label for imaging studies or as a site for further chemical modifications. Overall, the compound's characteristics suggest a multifaceted role in chemical and biological applications.

Formula: C₂₂H₂₃IN₂O

InChI: InChI=1S/C22H23IN2O/c1-24-13-7-6-8-16(24)14-25-15-19(17-9-3-5-12-21(17)25)22(26)18-10-2-4-11-20(18)23/h2-5,9-12,15-16H,6-8,13-14H2,1H3

InChI key: InChIKey=KSLCYQTUSSEGPT-UHFFFAOYSA-N

SMILES: C(N1C=2C(C(C(=O)C3=C(I)C=CC=C3)=C1)=CC=CC2)C4N(C)CCCC4

AM-2233

Controlled Product

CAS: 444912-75-8

Applications A potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor. (AM2233) had a very high affinity for the rat CB1 receptor, with most of the affinity residing with the (R)-enantiomer.Synthetic Cannabinoids
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Neumeyer, J., et al.: J. Med. Chem., 33, 521 (1990), D'Ambra, T., et al.: Bioorg. Med. Chem. Lett., 6, 17 (1996), Schatz, A., et al.: Toxicol. Appl. Pharmacol., 142, 278 (1997),

Formula: C₂₂H₂₃IN₂O

Color and Shape: Neat

Molecular weight: 458.34

Ref: TR-A575850

AM-2233 (1 mg/ml in Acetonitrile)

Controlled Product

CAS: 444912-75-8

Formula: C₂₂H₂₃IN₂O

Color and Shape: Single Solution

Molecular weight: 458.34

Ref: TR-KIT2845

AM 2233

Controlled Product

CAS: 444912-75-8

AM 2233, or AM-2233, belongs to the aminoakylindole cannabinergic ligand, acting as an agonist of the wild type human cannabinoid CB1 receptor (EC50 0.93 nM).

Formula: C₂₂H₂₃IN₂O

Purity: Min. 95%

Molecular weight: 458.34 g/mol

Ref: 3D-FA17341