CAS 4481-62-3

(+)-Betulonic acid

Description:

(+)-Betulonic acid is a naturally occurring triterpenoid compound derived from the bark of birch trees, particularly Betula species. It is characterized by its pentacyclic structure, which includes a cyclopentanoperhydrophenanthrene core. The compound exhibits a white to off-white crystalline appearance and is known for its potential biological activities, including anti-inflammatory and anticancer properties. (+)-Betulonic acid is soluble in organic solvents such as ethanol and chloroform but has limited solubility in water. Its molecular formula reflects a specific arrangement of carbon, hydrogen, and oxygen atoms, contributing to its unique chemical behavior. The compound's stereochemistry, indicated by the (+) designation, suggests it has a specific spatial arrangement that may influence its biological interactions. Research into (+)-Betulonic acid continues to explore its pharmacological potential, making it a subject of interest in natural product chemistry and medicinal research.

Formula: C₃₀H₄₆O₃

InChI: InChI=1S/C30H46O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-22,24H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,24+,27-,28+,29+,30-/m0/s1

InChI key: InChIKey=SLJTWDNVZKIDAU-SVAFSPIFSA-N

SMILES: C(O)(=O)[C@]12[C@@]([C@@]3([C@@](C)(CC1)[C@@]4(C)[C@](CC3)([C@]5(C)[C@@](CC4)(C(C)(C)C(=O)CC5)[H])[H])[H])([C@H](C(C)=C)CC2)[H]

Synonyms:

• 3-Oxobetulinic acid
• Betulonic Acid
• Betunolic acid
• Liquidambaric acid
• Liquidambronic acid
• Lup-20(29)-En-28-Oic Acid, 3-Oxo-
• Lup-20(30)-en-28-oic acid, 3-oxo-
• Mj 347-Rs
• NSC 152534
• 3-Oxolup-20(29)-en-28-oic acid

Betulonic Acid

CAS: 4481-62-3

Formula: C₃₀H₄₆O₃

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 454.70

Ref: 3B-B6085

Betulonic acid

CAS: 4481-62-3

Betulonic acid

Formula: C₃₀H₄₆O₃

Purity: 99%

Molecular weight: 454.68

Ref: 54-BUP11391

3-Oxolup-20(29)-En-28-Oic Acid

CAS: 4481-62-3

3-Oxolup-20(29)-En-28-Oic Acid

Formula: C₃₀H₄₆O₃

Purity: 98%

Molecular weight: 454.68

Ref: 54-OR1026271

Liquidambaric acid

CAS: 4481-62-3

Formula: C₃₀H₄₆O₃

Molecular weight: 454.70

Ref: 7W-GY1466

Liquidambaric acid

CAS: 4481-62-3

Betulonic acid has anti-cancer , anti-HIV,hepatoprotective and anti-inflammatory activities, it has antiviral activity against herpes simplex virus, it also suppresses ECHO 6 virus reproduction. Betulonic acid derivatives have a promising cytostatic activity in vitro and could be used as potential leads for the development of new type of anti-cancer agents.

Formula: C₃₀H₄₆O₃

Purity: 95%~99%

Molecular weight: 454.695

Ref: BP-BP0871

Betulonic acid (Standard)

CAS: 4481-62-3

Betulonic acid (Standard) is a reference standard for research and analysis in studies involving Betulonic acid. 1. Betulonic acid (Liquidambaric acid) amide stimulated the regenerative response in hepatocytes under conditions of combined toxic exposure and promoted recovery of their qualitative and quantitative characteristics, which was accompanied by a significant decrease in the severity of liver fibrosis and the absence of cirrhotic transformation of the liver. 2. Betulonic acid derivatives have a promising cytostatic activity in vitro and could be used as potential leads for the development of new type of anti-cancer agents. 3. Betulonic acid has antiholestatic effects in mice.

Formula: C₃₀H₄₆O₃

Molecular weight: 454.6844

Ref: TM-TMSM-2468

Betulonic Acid

CAS: 4481-62-3

Formula: C₃₀H₄₆O₃

Purity: %

Color and Shape: Solid

Molecular weight: 454.6844

Ref: IN-DA00DA51

Betulonic Acid

CAS: 4481-62-3

Formula: C₃₀H₄₆O₃

Molecular weight: 454.70

Ref: 4Z-B-227010

Betulonic acid

CAS: 4481-62-3

Betulonic acid amide aids liver recovery, reduces fibrosis, and shows potential as an anticancer agent with anticholestatic effects in mice.

Formula: C₃₀H₄₆O₃

Purity: 99.49%

Color and Shape: Solid

Molecular weight: 454.6844

Ref: TM-T5S0018

Betulonic acid

CAS: 4481-62-3

Carboxylic acid with ketone function

Formula: C₃₀H₄₆O₃

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 454.68

Ref: 5G-83839

Liquidambaric acid

CAS: 4481-62-3

Formula: C₃₀H₄₆O₃

Molecular weight: 454.7

Ref: BE-RMT13240

Betulonic acid

CAS: 4481-62-3

Formula: C₃₀H₄₆O₃

Molecular weight: 454.7

Ref: BE-RMCB105009

BETULONIC ACID

CAS: 4481-62-3

Formula: C₃₀H₄₆O₃

Purity: 99+%

Molecular weight: 454.695

Ref: 10-F546037

(+)-Betulonic Acid

Controlled Product

CAS: 4481-62-3

Applications (+)-Betulonic Acid shows potent cytotoxic activities against PC3, MGC-803, Bcap-37, and MCF-7 cell lines.
References Liu, M., et. al.: Molecules, 17, 6156 (2012)

Formula: C₃₀H₄₆O₃

Color and Shape: Neat

Molecular weight: 454.68

Ref: TR-B330270

Betulonicacid

CAS: 4481-62-3

Betulonic acid is a naturally occurring triterpenoid compound, which is sourced from the bark of certain species of birch trees, mainly Betula species. It exhibits anti-inflammatory and anti-cancer properties, primarily through the modulation of various signaling pathways involved in inflammation and apoptosis. Betulonic acid acts by inhibiting key enzymes and transcription factors, such as cyclooxygenase and NF-κB, thereby reducing the production of pro-inflammatory mediators and promoting cell death in cancerous cells.

Formula: C₃₀H₄₆O₃

Purity: Min. 95%

Molecular weight: 454.68 g/mol

Ref: 3D-FB73987