CAS 451-13-8

Homogentisic acid

Description:

Homogentisic acid, with the CAS number 451-13-8, is an organic compound that plays a significant role in the metabolic pathway of the amino acids phenylalanine and tyrosine. It is a colorless to pale yellow crystalline solid that is soluble in water and exhibits a slightly acidic nature. The chemical formula for homogentisic acid is C8H8O4, and it features a hydroxyl group and a carboxylic acid group, contributing to its reactivity and solubility. This compound is particularly notable for its involvement in the metabolic disorder alkaptonuria, where its accumulation leads to the darkening of urine upon exposure to air due to oxidation. Homogentisic acid can also participate in various biochemical reactions, including those related to the synthesis of other important biomolecules. Its structural characteristics include a 1,4-dihydroxyphenyl moiety, which is essential for its biological activity. Overall, homogentisic acid is a key intermediate in metabolic processes and has implications in both health and disease.

Formula: C₈H₈O₄

InChI: InChI=1/C8H8O4/c9-6-1-2-7(10)5(3-6)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)/p-1

InChI key: InChIKey=IGMNYECMUMZDDF-UHFFFAOYSA-N

SMILES: C(C(O)=O)C1=C(O)C=CC(O)=C1

Synonyms:

• (2,5-Dihydroxyphenyl)Acetate
• 2,5-Dihydroxy-α-toluic acid
• 2,5-Dihydroxybenzeneacetic acid
• 2-(2,5-Dihydroxyphenyl)acetic acid
• Acetic acid, (2,5-dihydroxyphenyl)-
• Alcapton
• Benzeneacetic acid, 2,5-dihydroxy-
• Homogentisic Acid Free Acid
• Homogentisic acid
• Homogentisic acid 2,5-Dihydroxyphenylacetic acid
• Homogentisicacid
• Homogentisinic acid
• NSC 88940
• 2,5-Dihydroxyphenylacetic acid
• 1,4-HYDROQUINONEACETIC ACID
• HOMOGENTISIC ACID(RG)
• 2,5-dihydroxy-benzeneaceticaci
• 2,5-dihydroxybenzeneaceticacid

Homogentisic acid

CAS: 451-13-8

2-(2,5-Dihydroxyphenyl)acetic acid

Formula: C₈H₈O₄

Purity: 98%

Molecular weight: 168.15

Ref: IN-DG6410

Homogentisic Acid

CAS: 451-13-8

Formula: C₈H₈O₄

Purity: >97.0%(T)(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 168.15

Ref: 3B-D1050

Homogentisic acid

CAS: 451-13-8

Homogentisic acid analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₈H₈O₄

Purity: (HPLC) ≥95%

Color and Shape: Powder

Molecular weight: 168.15

Ref: 11-6059

2-(2,5-Dihydroxyphenyl)acetic acid

CAS: 451-13-8

Formula: C₈H₈O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 168.1467

Ref: IN-DA003QY3

Homogentisic acid

CAS: 451-13-8

Homogentisic acid

Formula: C₈H₈O₄

Purity: ≥98%

Molecular weight: 168.15

Ref: 54-BUP00189

Homogentisic acid

CAS: 451-13-8

Homogentisic acid

Formula: C₈H₈O₄

Purity: >97.0%

Molecular weight: 168.147

Ref: 54-OR1000052

Homogentisic acid

CAS: 451-13-8

Homogentisic acid: antioxidant with anti-radical effects, protects against thermal cholesterol damage, melanin precursor, and Pfnek-1 inhibitor.

Formula: C₈H₈O₄

Purity: 98.35% - 99.62%

Color and Shape: Brown Solid

Molecular weight: 168.15

Ref: TM-TCS2070

Homogentisic Acid

CAS: 451-13-8

Applications An intermediate in the metabolism of tyrosine and phenylalanine. Occurs in plants and in the urine of alkaptonurics.
References Knox, W.E., et al.: Biochem. J., 49, 686 (1951), LaDu, B.N., et al.: J. Biol. Chem., 217, 777 (1955)

Formula: C₈H₈O₄

Color and Shape: Neat

Molecular weight: 168.15

Ref: TR-H593400

Homogentisic acid

CAS: 451-13-8

Precursor of melanine synthesis in bacteria

Formula: C₈H₈O₄

Purity: Min 96%

Color and Shape: White Powder

Molecular weight: 168.15 g/mol

Ref: 3D-FH23844

HOMOGENTISIC ACID

CAS: 451-13-8

Purity: 98%

Molecular weight: 168.147995

Ref: 10-F827702