CAS 451-69-4

3-(2-Fluorophenyl)-2-propenoic acid

Description:

3-(2-Fluorophenyl)-2-propenoic acid, also known as a derivative of cinnamic acid, is an organic compound characterized by its propenoic acid structure with a fluorophenyl substituent. It features a double bond between the second and third carbon atoms, contributing to its reactivity and potential applications in organic synthesis. The presence of the fluorine atom on the aromatic ring enhances its electrophilic properties, making it useful in various chemical reactions, including electrophilic aromatic substitution. This compound is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. Its chemical properties include the ability to undergo polymerization and participate in various coupling reactions, which are valuable in the development of pharmaceuticals and agrochemicals. Additionally, the fluorine substituent can influence the compound's biological activity and lipophilicity, making it a subject of interest in medicinal chemistry. Safety data should be consulted for handling and storage, as with all chemical substances.

Formula: C₉H₇FO₂

InChI: InChI=1S/C9H7FO2/c10-8-4-2-1-3-7(8)5-6-9(11)12/h1-6H,(H,11,12)

InChI key: InChIKey=IOUDZAFBPDDAMK-UHFFFAOYSA-N

SMILES: C(=CC(O)=O)C1=C(F)C=CC=C1

Synonyms:

• (2E)-3-(2-fluorophenyl)prop-2-enoate
• 2-Propenoic acid, 3-(2-fluorophenyl)-
• 3-(2-Fluorophenyl)-2-propenoic acid
• 3-(2-Fluorophenyl)acrylic acid
• 3-(2-Fluorophenyl)propenoic acid
• Cinnamic acid, o-fluoro-
• NSC 73989
• o-Fluorocinnamic acid
• 2-Fluorocinnamic acid

3-(2-Fluorophenyl)acrylic acid

CAS: 451-69-4

Formula: C₉H₇FO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 166.1491

Ref: IN-DA003HBR

2-Fluorocinnamic acid

CAS: 451-69-4

2-Fluorocinnamic acid

Purity: 98%

Color and Shape: White Solid

Molecular weight: 166.15g/mol

Ref: 54-PC3730

2-Fluorocinnamic acid

CAS: 451-69-4

Formula: C₉H₇FO₂

Molecular weight: 166.15

Ref: 7W-GK2493

2-Fluorocinnamic acid

CAS: 451-69-4

Formula: C₉H₇FO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 166.151

Ref: 10-F001440

2-Fluorocinnamic Acid

Controlled Product

CAS: 451-69-4

Applications 2-Fluorocinnamic acid, 98% (cas# 451-69-4) is a useful research chemical.

Formula: C₉H₇FO₂

Color and Shape: Neat

Molecular weight: 166.15

Ref: TR-F588643

2-Fluorocinnamic acid

CAS: 451-69-4

2-Fluorocinnamic acid is a cinnamic acid derivative that is used as an antibiotic. It has been shown to have bacteriostatic activity against a wide range of bacteria, including some strains of Staphylococcus and Streptococcus. 2-Fluorocinnamic acid binds to the enzyme that synthesizes amide and coumarin derivatives, thereby inhibiting its activity. This binding prevents the formation of bacterial cell wall and cell membrane components, leading to cell death. 2-Fluorocinnamic acid has also been used in the treatment of diabetic neuropathy. The drug interacts electronically with hydrogen fluoride (HF) and deionized water (DIW), with the rate of reaction increasing with pH. The reaction product is analyzed using high performance liquid chromatography (HPLC). 2-Fluorocinnamic acid inhibits bacterial growth by competing for substrate binding sites on enzymes such as β-lactamase, which are

Formula: C₉H₇FO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 166.15 g/mol

Ref: 3D-FF37093