CAS 452105-33-8

Formula: C16H13FN2O3

InChI: InChI=1S/C16H13FN2O3/c1-7-13(18-8(2)14(7)16(21)22)6-11-10-5-9(17)3-4-12(10)19-15(11)20/h3-6,18H,1-2H3,(H,19,20)(H,21,22)/b11-6-

InChI key: RBHBOUYXUXWCNJ-WDZFZDKYSA-N

SMILES: CC1=C(NC(=C1C(=O)O)C)/C=C\2/C3=C(C=CC(=C3)F)NC2=O

5-((5-Fluoro-2-Oxoindolin-3-Ylidene)Methyl)-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid

CAS: 452105-33-8

5-((5-Fluoro-2-Oxoindolin-3-Ylidene)Methyl)-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid

Formula: C₁₆H₁₃FN₂O₃

Purity: 95%

Molecular weight: 300.28

Ref: 54-PC109055

Sunitinib Process Impurity 1

CAS: 452105-33-8

Sunitinib Process Impurity 1

Purity: ≥95%

Molecular weight: 300.28g/mol

Ref: 54-BUP07854

5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 452105-33-8

Formula: C₁₆H₁₃FN₂O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 300.2844

Ref: IN-DA00DF37

5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid

Controlled Product

CAS: 452105-33-8

Applications Sunitinib intermediate.

Formula: C₁₆H₁₃FN₂O₃

Color and Shape: Neat

Molecular weight: 300.28

Ref: TR-F595150

Sunitinib Process Impurity 1

CAS: 452105-33-8

5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid is a sunitinib impurity.

Formula: C₁₆H₁₃FN₂O₃

Purity: 98.79%

Color and Shape: Orange Solid

Molecular weight: 300.28

Ref: TM-T9421

5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 452105-33-8

5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (5F2I) is a protein kinase inhibitor that was originally developed as a potential therapeutic agent for lung cancer. 5F2I inhibits the activity of protein kinases, which are enzymes that regulate cellular processes such as cell growth. It has been shown to inhibit the growth of prostate cancer cells in culture and to reduce the size of bladder tumors by 50% in animal models. 5F2I also has antihepatotoxic activity and can be used for the treatment of liver damage caused by alcohol abuse. This compound exists as two different polymorphs: one is soluble in organic solvents, while the other is soluble in water and methanol.

Formula: C₁₆H₁₃FN₂O₃

Purity: Min. 95 Area-%

Color and Shape: Orange Powder

Molecular weight: 300.28 g/mol

Ref: 3D-FF23383

Sunitinib Process Impurity 1

CAS: 452105-33-8

Formula: C₁₆H₁₃FN₂O₃

Molecular weight: 300.28

Ref: BE-RMCS226014

Sunitinib Carboxylic Acid Impurity

CAS: 452105-33-8

Formula: C₁₆H₁₃FN₂O₃

Molecular weight: 300.29

Ref: ST-EA-CP-S42002