CAS 45214-91-3
:BOC-GLU(OME)-OH
Description:
BOC-GLU(OME)-OH, also known as Boc-Glutamic acid methyl ester, is a derivative of glutamic acid, an amino acid that plays a crucial role in various biological processes. This compound features a tert-butyloxycarbonyl (Boc) protecting group, which is commonly used in peptide synthesis to protect the amino group of amino acids. The methyl ester group (OME) indicates that the carboxylic acid functional group of glutamic acid is esterified with a methanol molecule, enhancing its solubility and reactivity in organic synthesis. BOC-GLU(OME)-OH is typically a white to off-white solid, and it is soluble in organic solvents such as methanol and dichloromethane. This compound is often utilized in peptide synthesis and other organic reactions due to its ability to undergo selective deprotection and coupling reactions. Its stability and reactivity make it a valuable intermediate in the synthesis of various bioactive compounds and pharmaceuticals. Proper handling and storage conditions are essential to maintain its integrity and reactivity.
Formula:C11H19NO6
InChI:InChI=1S/C11H19NO6/c1-11(2,3)18-10(16)12-7(9(14)15)5-6-8(13)17-4/h7H,5-6H2,1-4H3,(H,12,16)(H,14,15)/t7-/m0/s1
InChI key:OHYMUFVCRVPMEY-ZETCQYMHSA-N
SMILES:CC(C)(C)OC(=O)N[C@@H](CCC(=O)OC)C(=O)O
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N-Boc-L-glutamic acid 5-methyl ester, 95%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo SciFormula:C11H19NO6Purity:95%Molecular weight:261.27(S)-2-((tert-Butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acid
CAS:Formula:C11H19NO6Purity:98%Color and Shape:SolidMolecular weight:261.2717N-Boc-L-glutamic Acid 5-Methyl Ester
CAS:Controlled ProductApplications N-Boc-L-glutamic Acid 5-Methyl Ester is an intermediate used in the synthesis of Isodesmosine Chloride Hydrate (Synthetic) (I815051), which is a component of elastin and also it is extremely hygroscopic and must be stored over a desiccant such as silica gel.
References Partridge, S., et al.: Nature, 209, 399 (1966)Formula:C11H19NO6Color and Shape:NeatMolecular weight:261.27t-Boc-L-Glu(OMe)-OH
CAS:t-Boc-L-Glu(OMe)-OHFormula:C11H19NO6Purity:0.98Color and Shape:White Solid-PowderMolecular weight:261.27166(S)-2-((tert-Butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acid
CAS:Formula:C11H19NO6Molecular weight:261.27(S)-2-((tert-Butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acid
CAS:(S)-2-((tert-Butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acidFormula:C11H19NO6Purity:97%Molecular weight:261.27Boc-L-glutamic acid gamma-methyl ester
CAS:Boc-L-glutamic acid gamma-methyl ester is a conjugate of glutamic acid and methyl ester. It has been shown to have neuroprotective properties by inhibiting the hydrophobic effect, which is the driving force for protein aggregation. This drug can be used as a treatment for neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. Boc-L-glutamic acid gamma-methyl ester binds with an alkyl group to the glutamate residue on the side chain of a model protein. The fluoroquinolone was found to be more potent than other drugs in this class because it has a higher affinity for glutamate residues.Formula:C11H19NO6Purity:Min. 95%Molecular weight:261.27 g/mol
