CAS: 453562-69-1 - Motesanib

Formula: C₂₂H₂₃N₅O

InChI: InChI=1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)

InChI key: InChIKey=RAHBGWKEPAQNFF-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C2C(=C1)NCC2(C)C)C3=CC=CN=C3NCC=4C=CN=CC4

Synonyms:

• 3-Pyridinecarboxamide, N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-
• Amg 706
• N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide
• N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide

Motesanib

CAS: 453562-69-1

• Formula: C₂₂H₂₃N₅O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 373.4509

Motesanib

CAS: 453562-69-1

• Formula: C₂₂H₂₃N₅O
• Purity: 99%
• Color and Shape: pale yellow solid
• Molecular weight: 373.45g/mol

Motesanib

CAS: 453562-69-1

Motesanib (AMG 706) orally blocks VEGFR, PDGFR, Kit, Ret; curbing angiogenesis and cancer cell growth.

• Formula: C₂₂H₂₃N₅O
• Purity: 98% - 98.87%
• Color and Shape: Solid
• Molecular weight: 373.45

Motesanib

CAS: 453562-69-1

Motesanib

CAS: 453562-69-1

Inhibitor of VEGFR, PDGR, c-Kit and Ret; inhibitor of angiogenesis

• Formula: C₂₂H₂₃N₅O
• Purity: Min. 95%
• Molecular weight: 373.45 g/mol

Motesanib

CAS: 453562-69-1

Applications Motesanib is an oral angiogenesis inhibitor, demonstrates clinical efficacy in advanced thymoma. References Rosen, …

• Formula: C₂₂H₂₃N₅O
• Color and Shape: Neat
• Molecular weight: 373.45