CAS 454-89-7

3-(Trifluoromethyl)benzaldehyde

Description:

3-(Trifluoromethyl)benzaldehyde, with the CAS number 454-89-7, is an aromatic aldehyde characterized by the presence of a trifluoromethyl group (-CF3) attached to the benzene ring at the meta position relative to the aldehyde functional group (-CHO). This compound typically appears as a colorless to pale yellow liquid with a distinctive aromatic odor. It is known for its high reactivity due to the electron-withdrawing nature of the trifluoromethyl group, which can influence its chemical behavior in various reactions, such as electrophilic aromatic substitution. The presence of the trifluoromethyl group also enhances the lipophilicity of the molecule, making it useful in organic synthesis and medicinal chemistry. 3-(Trifluoromethyl)benzaldehyde is soluble in organic solvents like ethanol and ether but has limited solubility in water. Safety precautions should be taken when handling this compound, as it may pose health risks, including irritation to the skin and respiratory system.

Formula: C₈H₅F₃O

InChI: InChI=1/C8H5F3O/c1-12-7-4-2-3-6(5-7)8(9,10)11/h2-5H,1H3

InChI key: InChIKey=NMTUHPSKJJYGML-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=CC(C=O)=CC=C1

Synonyms:

• 1-Methoxy-3-(Trifluoromethyl)Benzene
• 3-(Trifluoromethyl)benzaldehyde
• 3-(Trifluoromethyl)phenylcarboxaldehyde
• 3-Trifluoromethylbenzaldehyde
• Benzaldehyde, 3-(trifluoromethyl)-
• Benzotrifluoride-3-Carbaldehyde
• alpha,alpha,alpha-Trifluoro-3-tolualdehyde
• m-(Trifluoromethyl)benzaldehyde
• m-Tolualdehyde, α,α,α-trifluoro-
• m-Trifluoromethylbenzaldehyde
• α,α,α-Trifluoro-m-tolualdehyde
• m-Tolualdehyde, alpha,alpha,alpha-trifluoro-
• 3-(trifluoromethyl)-benzaldehyd
• ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLUALDEHYDE
• A,A,A-TRIFLUORO-META-TOLUALDEHYDE
• 3-TRIFLUORMETHYLBENZALDEHYDE
• A,A,A-TRIFLUORO-3-TOLUALDEHYDE
• 3-(Trifluoromethyl)benzaldehyde98%
• m-Trifluoromethylbenzaldehyde 3-Trifluoromethyl Benzaldehyde
• m-Trifluoromethylbenzaldehyde,97%
• α,α,α-Trifluoro-m-toluylaldehyde
• 3-TRIFLUOROMETHYLBENZYLDEHYDE
• ALPHA,ALPHA,ALPHA-TRIFLUORO-META-TOLUALDEHYDE
• MTF-BAD

3-(Trifluoromethyl)benzaldehyde

CAS: 454-89-7

Formula: C₈H₅F₃O

Purity: >95.0%(GC)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 174.12

Ref: 3B-T1399

3-(Trifluoromethyl)benzaldehyde, 97%

CAS: 454-89-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₅F₃O

Purity: 97%

Color and Shape: Liquid, Clear, colorless

Molecular weight: 174.12

Ref: 02-A10463

3-(Trifluoromethyl)benzaldehyde

CAS: 454-89-7

3-(Trifluoromethyl)benzaldehyde

Formula: C₈H₅F₃O

Purity: 97%

Color and Shape: Colourless Liquid

Molecular weight: 174.1199

Ref: 54-PC7500

3-(Trifluoromethyl)benzaldehyde

CAS: 454-89-7

3-(Trifluoromethyl)benzaldehyde

Formula: C₈H₅F₃O

Purity: ≥95%, 10 mM in DMSO

Molecular weight: 174.12

Ref: 54-BUP18925

3-(Trifluoromethyl)benzaldehyde

CAS: 454-89-7

Formula: C₈H₅F₃O

Purity: 97%

Color and Shape: Liquid

Molecular weight: 174.1199

Ref: IN-DA0033H8

3-Trifluoromethylbenzaldehyde

CAS: 454-89-7

Formula: C₈H₅F₃O

Molecular weight: 174.12

Ref: 7W-GK8345

3-(Trifluoromethyl)benzaldehyde

CAS: 454-89-7

3-Trifluoromethylbenzaldehyde: Sweet-flavored organic compound, used in flavoring, perfume, and as a synthesis intermediate.

Formula: C₈H₅F₃O

Purity: 97.55%

Color and Shape: Transparent Liquid

Molecular weight: 174.12

Ref: TM-T9367

3-(Trifluoromethyl)benzaldehyde

CAS: 454-89-7

Formula: C₈H₅F₃O

Purity: 97%

Color and Shape: Liquid, Clear

Molecular weight: 174.122

Ref: 10-F001471

Cinacalcet Impurity 23

CAS: 454-89-7

3-(Trifluoromethyl)benzaldehyde

Formula: C₈H₅F₃O

Purity: 97%

Molecular weight: 174.12

Ref: IN-DG20892

3-(Trifluoromethyl)benzaldehyde

Controlled Product

CAS: 454-89-7

Applications 3-(Trifluoromethyl)benzaldehyde is used as a reagent in the synthesis of 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-γ-butyrolactones as potent antitumor agents. Also used as a reagent in the synthesis of novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Le Floch, C., et al.: Eur. J. Med. Chem., 89, 654 (2015); Wang, L., et al.: Eur. J. Med. Chem., 89, 88 (2015)

Formula: C₈H₅F₃O

Color and Shape: Neat

Molecular weight: 174.12

Ref: TR-T792200

3-(Trifluoromethyl)benzaldehyde

CAS: 454-89-7

3-(Trifluoromethyl)benzaldehyde is an organic compound that has the chemical formula C8H7FO. It is a trifunctional molecule with three phenolic hydroxyl groups, which makes it a good candidate for drug design. 3-(Trifluoromethyl)benzaldehyde can be synthesized by reacting an imine with a chiral acid chloride in the presence of a base and a catalytic amount of DMAP. The reaction yield is low, but this synthetic method is efficient. 3-(Trifluoromethyl)benzaldehyde has been shown to inhibit the growth of Mycobacterium avium, but not Mycobacterium tuberculosis or other bacteria such as Listeria monocytogenes and Escherichia coli. This might be due to its ability to inhibit protein synthesis by binding to ribosomes. This compound also possesses anti-inflammatory properties and inhibits leukemia Hl-

Formula: C₈H₅F₃O

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 174.12 g/mol

Ref: 3D-FT29109

Cinacalcet Impurity 23

CAS: 454-89-7

Formula: C₈H₅F₃O

Molecular weight: 174.1

Ref: ST-EA-CP-C21054