CAS 455-14-1

4-(Trifluoromethyl)aniline

Description:

4-(Trifluoromethyl)aniline, with the CAS number 455-14-1, is an aromatic amine characterized by the presence of a trifluoromethyl group (-CF3) attached to the para position of an aniline structure. This compound typically appears as a colorless to pale yellow liquid or solid, depending on the temperature. It is known for its relatively high stability due to the strong electronegative nature of the trifluoromethyl group, which influences its chemical reactivity and solubility properties. The presence of the trifluoromethyl group enhances lipophilicity, making it more soluble in organic solvents than in water. 4-(Trifluoromethyl)aniline is utilized in various applications, including as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. However, it is important to handle this compound with care, as aromatic amines can pose health risks, including potential carcinogenicity. Proper safety measures should be observed when working with this substance in laboratory or industrial settings.

Formula: C₇H₆F₃N

InChI: InChI=1S/C7H6F3N/c8-7(9,10)5-1-3-6(11)4-2-5/h1-4H,11H2

InChI key: InChIKey=ODGIMMLDVSWADK-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=CC=C(N)C=C1

Synonyms:

• 4-Aminobenzotrifluoride
• p-Trifluoromethylaniline
• Trifluoromehylphenylanilide
• 4-Trifluoromethyl Aniline
• 4-Amino Trifluorotoluene
• Aminobenzotrifluoride, 4-
• (4-(Trifluoromethyl)phenyl)amine
• 1-Amino-4-(trifluoromethyl)benzene
• 4-(Trifluoromethyl)benzenamine
• 4-Amino-α,α,α-benzotrifluoride
• Benzenamine, 4-(trifluoromethyl)-
• Benzotrifluoride, 4-Amino-
• Nsc 10337
• p-(Trifluoromethyl)aniline
• p-Aminobenzotrifluoride
• p-Amino-α,α,α-trifluorotoluene
• p-Toluidine, α,α,α-trifluoro-
• p-Trifluoromethylphenylamine
• α,α,α-Trifluoro-p-toluidine
• α,α,α-Trifluor-p-toluidin

LEFLUNOMIDE IMPURITY A CRS

CAS: 455-14-1

LEFLUNOMIDE IMPURITY A CRS

Ref: 41-Y0000487

4-Aminobenzotrifluoride

CAS: 455-14-1

4-Aminobenzotrifluoride

Formula: C₇H₆F₃N

Purity: 97%

Color and Shape: Yellow Liquid

Molecular weight: 161.12444

Ref: 54-PC1040

4-(Trifluoromethyl)Aniline

CAS: 455-14-1

Formula: C₇H₆F₃N

Purity: 95%

Color and Shape: Liquid

Molecular weight: 161.1244

Ref: IN-DA003KR0

4-Aminobenzotrifluoride

CAS: 455-14-1

Formula: C₇H₆F₃N

Molecular weight: 161.13

Ref: 7W-GK5650

4-Aminobenzotrifluoride

CAS: 455-14-1

Formula: C₇H₆F₃N

Purity: 98%

Color and Shape: Liquid, Clear

Molecular weight: 161.127

Ref: 10-F001401

Leflunomide impurity A

CAS: 455-14-1

4-(Trifluoromethyl)aniline

Formula: C₇H₆F₃N

Purity: 98%

Molecular weight: 161.12

Ref: IN-DG10447

Leflunomide EP Impurity A

CAS: 455-14-1

Formula: C₇H₆F₃N

Molecular weight: 161.13

Ref: 4Z-L-048

Leflunomide EP Impurity A

CAS: 455-14-1

Formula: C₇H₆F₃N

Molecular weight: 161.12

Ref: ST-EA-CP-L12001

4-(Trifluoromethyl)aniline

Controlled Product

CAS: 455-14-1

Impurity Leflunomide EP Impurity A; Leflunomide USP Related Compound A
Applications 4-(Trifluoromethyl)aniline (Leflunomide EP Impurity A; Leflunomide USP Related Compound A) is a 4-Substituted aniline derivatives exert special hematotoxicity on the red blood cells and induce leukocytosis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Weber, W., et al.: Pharmacol. Rev., 37, 25 (1985), Hein, D., et al.: Carcinogenesis, 14, 1633 (1993), Payton, M., et al.: Microbiology, 147, 1137 (2001), Mushtaq, A., et al.: J. Biol. Chem., 277, 12175 (2002),

Formula: C₇H₆F₃N

Color and Shape: Neat

Molecular weight: 161.12

Ref: TR-T791050

4-Aminobenzotrifluoride

CAS: 455-14-1

4-Aminobenzotrifluoride is a chemical compound that belongs to the group of nitroso compounds. It has been shown to have antiproliferation activity in vitro and in vivo. 4-Aminobenzotrifluoride is synthesized by reacting sodium nitrite with p-hydroxybenzoic acid in the presence of an organic acid, such as acetic acid or formic acid, to produce diazonium salt. The diazonium salt is then reacted with an inorganic acid, such as hydrochloric acid or sulfuric acid. This reaction produces 4-aminobenzotrifluoride and water.

Formula: C₇H₆F₃N

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 161.12 g/mol

Ref: 3D-FA00019

4-Aminobenzotrifluoride

CAS: 455-14-1

Formula: C₇H₆F₃N

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Light orange to Yellow clear liquid

Molecular weight: 161.13

Ref: 3B-A0662

Leflunomide Related Compound A (4-(trifluoromethyl)aniline)

CAS: 455-14-1

Toluidines (aminotoluenes) and their derivatives, salts thereof

Formula: C₇H₆F₃N

Color and Shape: White Light Yellow Liquid

Molecular weight: 161.04523

Ref: 45-1357045