CAS 457081-03-7

9-Fluoro-2-(2-methyl-2-propanyl)-1,6-dihydro-7H-benzo[h]imidazo[4,5-f]isoquinolin-7-one

Description:

9-Fluoro-2-(2-methyl-2-propanyl)-1,6-dihydro-7H-benzo[h]imidazo[4,5-f]isoquinolin-7-one is a complex organic compound characterized by its unique structural features, including a fused benzoimidazole and isoquinoline framework. This compound contains a fluorine atom, which can influence its electronic properties and reactivity. The presence of a bulky isopropyl group contributes to its steric hindrance, potentially affecting its biological activity and interactions with other molecules. The dihydro form indicates that it has a saturated bond within its structure, which may impact its stability and solubility. This compound is of interest in medicinal chemistry, particularly for its potential pharmacological applications, as derivatives of benzoimidazole and isoquinoline are often explored for their biological activities, including antitumor and antimicrobial properties. Its specific characteristics, such as melting point, solubility, and spectral data, would typically be determined through experimental methods and are essential for understanding its behavior in various chemical environments.

Formula: C₁₈H₁₆FN₃O

Synonyms:

• (3E)-4-(4-fluorophenyl)-1-(1H-imidazol-1-yl)-2-(pyridin-3-yl)but-3-en-2-ol
• Merck-5
• Merk-5
• Jak Inhibitor I
• Cmp 6
• 2-(1,1-Dimethylethyl)-9-fluoro-1,6-dihydro-7H-benz[H]imidazo[4,5-F]isoquinolin-7-one
• Jak inhibitor I (merck 5)
• 2-tert-butyl-9-fluoro-3H-benzo[h]imidazo[4,5-f]isoquinolin-7(6H)-one

2-(tert-Butyl)-9-fluoro-1,6-dihydro-7H-benzo[h]imidazo[4,5-f]isoquinolin-7-one

CAS: 457081-03-7

Formula: C₁₈H₁₆FN₃O

Purity: 98%

Color and Shape: Solid

Molecular weight: 309.3375

Ref: IN-DA00DAQP

Pyridone 6

CAS: 457081-03-7

Pyridone 6

Purity: ≥95%

Molecular weight: 309.34g/mol

Ref: 54-BUP08096

Merck-5

CAS: 457081-03-7

Ref: 7W-GW2210

Pyridone 6

CAS: 457081-03-7

Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).

Formula: C₁₈H₁₆FN₃O

Purity: 97.1% - 98.74%

Color and Shape: Solid

Molecular weight: 309.34

Ref: TM-T3080

Pyridone 6

CAS: 457081-03-7

Formula: C₁₈H₁₆FN₃O

Purity: >90%

Color and Shape: Neat

Molecular weight: 309.34

Ref: TR-P991730

PYRIDONE 6

CAS: 457081-03-7

Formula: C₁₈H₁₆FN₃O

Purity: 98%

Molecular weight: 309.344

Ref: 10-F533492