Pyridone 6
CAS: 457081-03-7
Ref. TM-T3080
| 1mg | 81.00 € | ||
| 2mg | 105.00 € | ||
| 5mg | 159.00 € | ||
| 10mg | 218.00 € | ||
| 25mg | 441.00 € | ||
| 50mg | 648.00 € | ||
| 100mg | 918.00 € | ||
| 500mg | 1,838.00 € | ||
| 1ml*10 (DMSO) | 173.00 € |
Estimated delivery in United States, on Thursday 9 May 2024
Product Information
Name:
Pyridone 6
Synonyms:
- Janus-Associated Kinase Inhibitor I, JAK Inhibitor, CMP 6, JAK Inhibitor I
- (3E)-4-(4-fluorophenyl)-1-(1H-imidazol-1-yl)-2-(pyridin-3-yl)but-3-en-2-ol
- Merck-5
- Merk-5
- Jak Inhibitor I
- Cmp 6
- 2-(1,1-Dimethylethyl)-9-fluoro-1,6-dihydro-7H-benz[H]imidazo[4,5-F]isoquinolin-7-one
- Jak inhibitor I (merck 5)
- 2-tert-butyl-9-fluoro-3H-benzo[h]imidazo[4,5-f]isoquinolin-7(6H)-one
CAS:
Description:
Pyridone 6 (JAK Inhibitor)(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM); displaying significantly weaker affinities (130 nM to 10 mM) for other protein tyrosine kinases.
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
309.34
Formula:
C18H16FN3O
Purity:
98.74%
Color/Form:
Solid
InChI:
InChI=1S/C18H16FN3O/c1-18(2,3)17-21-14-10-5-4-9(19)8-12(10)13-11(15(14)22-17)6-7-20-16(13)23/h4-8H,1-3H3,(H,20,23)(H,21,22)
InChI key:
InChIKey=VNDWQCSOSCCWIP-UHFFFAOYSA-N
SMILES:
CC(C)(C)c1nc2c3cc[nH]c(=O)c3c3cc(F)ccc3c2[nH]1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
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