CAS 459789-99-2

(3alpha,5beta,6alpha,7alpha)-6-Ethyl-3,7-dihydroxycholan-24-oic acid

Description:

The chemical substance known as (3alpha,5beta,6alpha,7alpha)-6-Ethyl-3,7-dihydroxycholan-24-oic acid, with the CAS number 459789-99-2, is a steroid derivative characterized by its specific structural features. It belongs to the class of bile acids and is notable for containing hydroxyl groups at the 3 and 7 positions, which contribute to its solubility and biological activity. The presence of an ethyl group at the 6 position modifies its hydrophobic and hydrophilic balance, influencing its interaction with biological membranes and receptors. This compound is likely to exhibit significant biological activity, potentially affecting lipid metabolism and signaling pathways. Its stereochemistry, indicated by the alpha and beta designations, plays a crucial role in determining its pharmacological properties and interactions with enzymes and transport proteins. Overall, this compound's unique structure suggests potential applications in medicinal chemistry and biochemistry, particularly in the study of metabolic disorders and therapeutic interventions related to bile acid metabolism.

Formula: C₂₆H₄₄O₄

InChI: InChI=1S/C26H44O4/c1-5-17-21-14-16(27)10-12-26(21,4)20-11-13-25(3)18(15(2)6-9-22(28)29)7-8-19(25)23(20)24(17)30/h15-21,23-24,27,30H,5-14H2,1-4H3,(H,28,29)/t15-,16-,17-,18-,19+,20+,21+,23+,24-,25-,26-/m1/s1

InChI key: InChIKey=ZXERDUOLZKYMJM-ZWECCWDJSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCC(O)=O)C)(CC4)[H])[H])([C@H](O)[C@H](CC)[C@@]1(C[C@H](O)CC2)[H])[H])[H]

Synonyms:

• (3α,5β,6α,7α)-6-Ethyl-3,7-dihydroxycholan-24-oic acid
• 3α,7β-Dihydroxy-6α-ethyl-5β-cholan-24-oic acid
• 6-Ecdca
• 6-Ethylchenodeoxycholic acid
• 6α-Ethylchenodeoxycholic acid
• Cholan-24-oic acid, 6-ethyl-3,7-dihydroxy-, (3α,5β,6α,7α)-
• Int 747
• Obeticholic Acid
• Ocaliva
• 6-Ethyl-cdca
• 6alpha-Ethyl-chenodeoxycholic acid
• 6alpha-ethyl-chenodeoxycholic acid, 6-ECDCA, INT-747
• (3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-cholan-24-oic acid
• C15636
• (R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
• Obetichlolic Acid
• 6-Ethylchenodeoxycholic acid(Obeticholic Acid)
• DSP-1747
• 9470

Obetichloic acid

CAS: 459789-99-2

Formula: C₂₆H₄₄O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 420.6252

Ref: IN-DA00368R

Obeticholic Acid

CAS: 459789-99-2

Obeticholic Acid

Purity: ≥98%

Molecular weight: 420.63g/mol

Ref: 54-BUP17779

Obeticholic Acid

CAS: 459789-99-2

Formula: C₂₆H₄₄O₄

Color and Shape: White To Off-White Solid

Molecular weight: 420.63

Ref: 4Z-O-056001

Obeticholic Acid

CAS: 459789-99-2

Color and Shape: Neat

Ref: 86-MM3805.00

Obeticholic Acid

CAS: 459789-99-2

Formula: C₂₆H₄₄O₄

Purity: >97.0%(GC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 420.63

Ref: 3B-O0641

Obeticholic Acid

CAS: 459789-99-2

Molecular weight: 420.634002685547

Ref: 10-F951505

6-ECDCA

CAS: 459789-99-2

Formula: C₂₆H₄₄O₄

Purity: ≥ 95%

Color and Shape: White powder

Molecular weight: 420.6

Ref: 7W-GL0816

Obeticholic Acid

CAS: 459789-99-2

Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.

Formula: C₂₆H₄₄O₄

Purity: 99.88% - 99.97%

Color and Shape: Solid

Molecular weight: 420.63

Ref: TM-T1789

6-Ethylchenodeoxycholic Acid

Controlled Product

CAS: 459789-99-2

Applications 6-Ethylchenodeoxycholic Acid is a derivative of the bile acid Chenodeoxycholic Acid (C291900). 6-Ethylchenodeoxycholic Acid is a potent activator of the farnesoid X nuclear receptor which reduces liver fat and fibrosis in animal models of fatty liver disease.
References Neuschwander-Tetri, B.A., et al.: Lancet., 385, 956 (2015);

Formula: C₂₆H₄₄O₄

Color and Shape: White To Off-White

Molecular weight: 420.63

Ref: TR-E899810