CAS 459789-99-2
:(3alpha,5beta,6alpha,7alpha)-6-Ethyl-3,7-dihydroxycholan-24-oic acid
Description:
The chemical substance known as (3alpha,5beta,6alpha,7alpha)-6-Ethyl-3,7-dihydroxycholan-24-oic acid, with the CAS number 459789-99-2, is a steroid derivative characterized by its specific structural features. It belongs to the class of bile acids and is notable for containing hydroxyl groups at the 3 and 7 positions, which contribute to its solubility and biological activity. The presence of an ethyl group at the 6 position modifies its hydrophobic and hydrophilic balance, influencing its interaction with biological membranes and receptors. This compound is likely to exhibit significant biological activity, potentially affecting lipid metabolism and signaling pathways. Its stereochemistry, indicated by the alpha and beta designations, plays a crucial role in determining its pharmacological properties and interactions with enzymes and transport proteins. Overall, this compound's unique structure suggests potential applications in medicinal chemistry and biochemistry, particularly in the study of metabolic disorders and therapeutic interventions related to bile acid metabolism.
Formula:C26H44O4
InChI:InChI=1S/C26H44O4/c1-5-17-21-14-16(27)10-12-26(21,4)20-11-13-25(3)18(15(2)6-9-22(28)29)7-8-19(25)23(20)24(17)30/h15-21,23-24,27,30H,5-14H2,1-4H3,(H,28,29)/t15-,16-,17-,18-,19+,20+,21+,23+,24-,25-,26-/m1/s1
InChI key:InChIKey=ZXERDUOLZKYMJM-ZWECCWDJSA-N
SMILES:C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCC(O)=O)C)(CC4)[H])[H])([C@H](O)[C@H](CC)[C@@]1(C[C@H](O)CC2)[H])[H])[H]
Synonyms:- (3α,5β,6α,7α)-6-Ethyl-3,7-dihydroxycholan-24-oic acid
- 3α,7β-Dihydroxy-6α-ethyl-5β-cholan-24-oic acid
- 6-Ecdca
- 6-Ethylchenodeoxycholic acid
- 6α-Ethylchenodeoxycholic acid
- Cholan-24-oic acid, 6-ethyl-3,7-dihydroxy-, (3α,5β,6α,7α)-
- Int 747
- Obeticholic Acid
- Ocaliva
- 6-Ethyl-cdca
- 6alpha-Ethyl-chenodeoxycholic acid
- 6alpha-ethyl-chenodeoxycholic acid, 6-ECDCA, INT-747
- (3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-cholan-24-oic acid
- C15636
- (R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
- Obetichlolic Acid
- 6-Ethylchenodeoxycholic acid(Obeticholic Acid)
- DSP-1747
- 9470
- See more synonyms
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Found 11 products.
Obeticholic Acid
CAS:Formula:C26H44O4Purity:>97.0%(GC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:420.63Obeticholic Acid
CAS:Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.Formula:C26H44O4Purity:99.88% - 99.97%Color and Shape:SolidMolecular weight:420.63Ref: TM-T1789
5mg46.00€10mg50.00€1mL*10mM (DMSO)50.00€25mg78.00€50mg94.00€100mg155.00€200mg259.00€500mg477.00€Obeticholic Acid
CAS:(R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acidFormula:C26H44O4Purity:98%Molecular weight:420.636-Ethylchenodeoxycholic Acid
CAS:Controlled ProductApplications 6-Ethylchenodeoxycholic Acid is a derivative of the bile acid Chenodeoxycholic Acid (C291900). 6-Ethylchenodeoxycholic Acid is a potent activator of the farnesoid X nuclear receptor which reduces liver fat and fibrosis in animal models of fatty liver disease.
References Neuschwander-Tetri, B.A., et al.: Lancet., 385, 956 (2015);Formula:C26H44O4Color and Shape:NeatMolecular weight:420.63
