CAS 465-99-6

Hederagenin

Description:

Hederagenin is a triterpenoid saponin, specifically a pentacyclic compound, which is primarily derived from various plant sources, including ivy (Hedera helix). It is characterized by its steroid-like structure, featuring a fused ring system that contributes to its biological activity. Hederagenin exhibits a range of pharmacological properties, including anti-inflammatory, antioxidant, and potential anticancer effects, making it of interest in medicinal chemistry and natural product research. The compound is typically found in the form of glycosides, which can enhance its solubility and bioavailability. In terms of physical properties, hederagenin is generally a white to off-white powder, and it is soluble in organic solvents but has limited solubility in water. Its molecular formula reflects a complex arrangement of carbon, hydrogen, and oxygen atoms, which is typical for triterpenoids. Research continues to explore its mechanisms of action and potential therapeutic applications, particularly in the context of traditional medicine and modern pharmacology.

Formula: C₃₀H₄₈O₄

InChI: InChI=1S/C30H48O4/c1-25(2)13-15-30(24(33)34)16-14-28(5)19(20(30)17-25)7-8-22-26(3)11-10-23(32)27(4,18-31)21(26)9-12-29(22,28)6/h7,20-23,31-32H,8-18H2,1-6H3,(H,33,34)/t20-,21+,22+,23-,26-,27-,28+,29+,30-/m0/s1

InChI key: InChIKey=PGOYMURMZNDHNS-MYPRUECHSA-N

SMILES: C[C@]12C([C@]3([C@@](C(O)=O)(CC1)CCC(C)(C)C3)[H])=CC[C@]4([C@@]2(C)CC[C@@]5([C@]4(C)CC[C@H](O)[C@]5(CO)C)[H])[H]

Synonyms:

• (3-beta,4-alpha)-3,23-Dihydroxyolean-12-en-28-oic acid
• (3Beta)-3,23-Dihydroxyolean-12-En-28-Oic Acid
• (3Beta)-3,24-Dihydroxyolean-12-En-28-Oic Acid
• (3Beta,5Xi,9Xi,18Xi)-3,23-Dihydroxyolean-12-En-28-Oic Acid
• (3beta,4alpha)-3,23-Dihydroxyolean-12-en-28-oic acid
• (3β,4α)-3,23-Dihydroxyolean-12-en-28-oic acid
• 3β,23-Dihydroxyolean-12-en-28-oic acid
• Astrantiagenin E
• Caulosapogenin
• Hederagenic acid
• Hederagenine
• Hederagenol
• Helexin
• Nsc 24954
• Olean-12-en-28-oic acid, 3,23-dihydroxy-, (3-beta,4-alpha)-
• Olean-12-en-28-oic acid, 3,23-dihydroxy-, (3beta,4alpha)- (9CI)
• Olean-12-en-28-oic acid, 3,23-dihydroxy-, (3β,4α)-
• Olean-12-en-28-oic acid, 3-beta,23-dihydroxy- (6CI,7CI,8CI)
• Olean-12-en-28-oic acid, 3beta,23-dihydroxy- (8CI)
• Olean-12-en-28-oic acid, 3β,23-dihydroxy-

Hederagenin

CAS: 465-99-6

Formula: C₃₀H₄₈O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 472.71

Ref: 3B-H1645

Hederagenin

CAS: 465-99-6

Hederagenin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₃₀H₄₈O₄

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 472.71

Ref: 11-0035S

Hederagenin

CAS: 465-99-6

Hederagenin

Purity: ≥98%

Molecular weight: 472.7g/mol

Ref: 54-BUP00171

Hederagenin

CAS: 465-99-6

Formula: C₃₀H₄₈O₄

Molecular weight: 472.71

Ref: 7W-GY0668

Hederagenin

CAS: 465-99-6

Formula: C₃₀H₄₈O₄

Purity: 95%~99%

Molecular weight: 472.71

Ref: BP-BP0710

Hederagenin

CAS: 465-99-6

Hederagenin

Formula: C₃₀H₄₈O₄

Purity: 98%

Color and Shape: almost white powder

Molecular weight: 472.70g/mol

Ref: 54-BIDF1006

Hederagenin

CAS: 465-99-6

Hederagenin (Hederagenol) is a triterpenoid saponin inhibiting LPS-stimulated expression of iNOS, COX-2, and NF-κB.

Formula: C₃₀H₄₈O₄

Purity: 98.47% - 99.11%

Color and Shape: Solid

Molecular weight: 472.70

Ref: TM-T3039

Hederagenin

CAS: 465-99-6

Carboxylic acid with alcohol function

Formula: C₃₀H₄₈O₄

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 472.71

Ref: 5G-89706

Hederagenin

CAS: 465-99-6

Applications Triterpenoid which can inhibit the proliferation of leukemia HL-60 cells.
References Cho, J., et al.: Pulmon. Pharmacol. Ther., 23, 190 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Saha, S., et al.: J. Agric. Food Chem., 58, 434 (2010),

Formula: C₃₀H₄₈O₄

Color and Shape: Neat

Molecular weight: 472.70

Ref: TR-H129990

Hederagenin

Controlled Product

CAS: 465-99-6

Hederagenin is a triterpenoid saponin, which is a naturally occurring organic compound typically found in various plant species, particularly in the Araliaceae family. It is derived from the hydrolysis of saponins such as hederacoside C, present in plants like ivy (Hedera helix). This compound exhibits a wide array of biological activities due to its ability to interact with cellular membranes and proteins.

Formula: C₃₀H₄₈O₄

Purity: Min. 95.0 Area-%

Color and Shape: White Powder

Molecular weight: 472.70 g/mol

Ref: 3D-FH23742

Hederagenin

Controlled Product

CAS: 465-99-6

Hederagenin is a pentacyclic triterpenoid saponin, which is a naturally occurring compound derived primarily from the plant Hedera helix, commonly known as English ivy. Hederagenin is characterized by its capability to modulate inflammatory pathways and its biological activity against various microorganisms. The mode of action of hederagenin involves the inhibition of specific enzymes and signaling pathways associated with inflammation, such as the NF-κB pathway, which plays a pivotal role in cellular responses. Furthermore, it disrupts microbial cell membranes, leading to reduced microbial viability.

Formula: C₃₀H₄₈O₄

Purity: Min. 97 Area-%

Molecular weight: 472.70 g/mol

Ref: 3D-Q-100493

HEDERAGENIN

CAS: 465-99-6

Purity: 98%

Molecular weight: 472.7099915

Ref: 10-F859141