CAS 465-99-6
:Hederagenin
Description:
Hederagenin is a triterpenoid saponin, specifically a pentacyclic compound, which is primarily derived from various plant sources, including ivy (Hedera helix). It is characterized by its steroid-like structure, featuring a fused ring system that contributes to its biological activity. Hederagenin exhibits a range of pharmacological properties, including anti-inflammatory, antioxidant, and potential anticancer effects, making it of interest in medicinal chemistry and natural product research. The compound is typically found in the form of glycosides, which can enhance its solubility and bioavailability. In terms of physical properties, hederagenin is generally a white to off-white powder, and it is soluble in organic solvents but has limited solubility in water. Its molecular formula reflects a complex arrangement of carbon, hydrogen, and oxygen atoms, which is typical for triterpenoids. Research continues to explore its mechanisms of action and potential therapeutic applications, particularly in the context of traditional medicine and modern pharmacology.
Formula:C30H48O4
InChI:InChI=1S/C30H48O4/c1-25(2)13-15-30(24(33)34)16-14-28(5)19(20(30)17-25)7-8-22-26(3)11-10-23(32)27(4,18-31)21(26)9-12-29(22,28)6/h7,20-23,31-32H,8-18H2,1-6H3,(H,33,34)/t20-,21+,22+,23-,26-,27-,28+,29+,30-/m0/s1
InChI key:InChIKey=PGOYMURMZNDHNS-MYPRUECHSA-N
SMILES:C[C@]12C([C@]3([C@@](C(O)=O)(CC1)CCC(C)(C)C3)[H])=CC[C@]4([C@@]2(C)CC[C@@]5([C@]4(C)CC[C@H](O)[C@]5(CO)C)[H])[H]
Synonyms:- (3-beta,4-alpha)-3,23-Dihydroxyolean-12-en-28-oic acid
- (3Beta)-3,23-Dihydroxyolean-12-En-28-Oic Acid
- (3Beta)-3,24-Dihydroxyolean-12-En-28-Oic Acid
- (3Beta,5Xi,9Xi,18Xi)-3,23-Dihydroxyolean-12-En-28-Oic Acid
- (3beta,4alpha)-3,23-Dihydroxyolean-12-en-28-oic acid
- (3β,4α)-3,23-Dihydroxyolean-12-en-28-oic acid
- 3β,23-Dihydroxyolean-12-en-28-oic acid
- Astrantiagenin E
- Caulosapogenin
- Hederagenic acid
- Hederagenine
- Hederagenol
- Helexin
- Nsc 24954
- Olean-12-en-28-oic acid, 3,23-dihydroxy-, (3-beta,4-alpha)-
- Olean-12-en-28-oic acid, 3,23-dihydroxy-, (3beta,4alpha)- (9CI)
- Olean-12-en-28-oic acid, 3,23-dihydroxy-, (3β,4α)-
- Olean-12-en-28-oic acid, 3-beta,23-dihydroxy- (6CI,7CI,8CI)
- Olean-12-en-28-oic acid, 3beta,23-dihydroxy- (8CI)
- Olean-12-en-28-oic acid, 3β,23-dihydroxy-
- See more synonyms
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Hederagenin
CAS:Formula:C30H48O4Purity:>98.0%(HPLC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:472.71Hederagenin (Standard)
CAS:Hederagenin (Standard) is a reference standard for research and analysis in studies involving Hederagenin. Hederagenin (Hederagenol) is a triterpenoid saponin inhibiting LPS-stimulated expression of iNOS, COX-2, and NF-κB.Formula:C30H48O4Molecular weight:472.6997Hederagenin
CAS:Hederagenin analytical standard provided with w/w absolute assay, to be used for quantitative titration.Formula:C30H48O4Purity:(HPLC) ≥98%Color and Shape:PowderMolecular weight:472.71Hederagenin
CAS:Applications Triterpenoid which can inhibit the proliferation of leukemia HL-60 cells.
References Cho, J., et al.: Pulmon. Pharmacol. Ther., 23, 190 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Saha, S., et al.: J. Agric. Food Chem., 58, 434 (2010),Formula:C30H48O4Color and Shape:NeatMolecular weight:472.7(4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-10-Hydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid
CAS:(4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-10-Hydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acidFormula:C30H48O4Purity:98%Molecular weight:472.7Hederagenin
CAS:Hederagenin (Hederagenol) is a triterpenoid saponin inhibiting LPS-stimulated expression of iNOS, COX-2, and NF-κB.Formula:C30H48O4Purity:98.47% - 99.11%Color and Shape:SolidMolecular weight:472.6997Hederagenin
CAS:Carboxylic acid with alcohol functionFormula:C30H48O4Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:472.71Hederagenin
CAS:Controlled ProductHederagenin is a pentacyclic triterpenoid saponin, which is a naturally occurring compound derived primarily from the plant Hedera helix, commonly known as English ivy. Hederagenin is characterized by its capability to modulate inflammatory pathways and its biological activity against various microorganisms. The mode of action of hederagenin involves the inhibition of specific enzymes and signaling pathways associated with inflammation, such as the NF-κB pathway, which plays a pivotal role in cellular responses. Furthermore, it disrupts microbial cell membranes, leading to reduced microbial viability.Formula:C30H48O4Purity:Min. 97 Area-%Molecular weight:472.70 g/molHederagenin
CAS:Controlled ProductHederagenin is a triterpenoid saponin, which is a naturally occurring organic compound typically found in various plant species, particularly in the Araliaceae family. It is derived from the hydrolysis of saponins such as hederacoside C, present in plants like ivy (Hedera helix). This compound exhibits a wide array of biological activities due to its ability to interact with cellular membranes and proteins.Formula:C30H48O4Purity:Min. 95.0 Area-%Color and Shape:White PowderMolecular weight:472.70 g/mol
