CAS 470-37-1: Cinobufagin
Description:Cinobufagin is a naturally occurring compound classified as a bufadienolide, which is a type of steroidal glycoside. It is primarily derived from the skin of certain toads, particularly those in the Bufo genus. This compound exhibits a range of biological activities, including cardiotonic effects, which can influence heart muscle contractions. Cinobufagin has been studied for its potential therapeutic applications, particularly in traditional medicine, where it is believed to possess anti-cancer, anti-inflammatory, and immunomodulatory properties. The substance is characterized by its complex molecular structure, which includes a steroid backbone and specific functional groups that contribute to its biological activity. However, due to its potent effects, cinobufagin can also exhibit toxicity, necessitating careful consideration in its use. Research continues to explore its mechanisms of action and potential clinical applications, while also addressing safety and efficacy concerns. As with many natural compounds, the pharmacological profile of cinobufagin is of significant interest in both traditional and modern medicinal contexts.
Formula:C26H34O6
InChI:InChI=1S/C26H34O6/c1-14(27)31-22-21(15-4-7-20(29)30-13-15)25(3)11-9-18-19(26(25)23(22)32-26)6-5-16-12-17(28)8-10-24(16,18)2/h4,7,13,16-19,21-23,28H,5-6,8-12H2,1-3H3/t16-,17+,18+,19-,21+,22-,23-,24+,25-,26-/m1/s1
InChI key:InChIKey=SCULJPGYOQQXTK-OLRINKBESA-N
SMILES:O=C1OC=C(C=C1)C2C(OC(=O)C)C3OC34C5CCC6CC(O)CCC6(C)C5CCC24C
- Synonyms:
- (3Beta,5Beta,15Beta,16Beta)-16-(Acetyloxy)-3-Hydroxy-14,15-Epoxybufa-20,22-Dienolide
- (3beta,5beta,8xi,9xi,10xi,13xi,14beta,15beta,16beta,17beta)-3-hydroxy-17-(2-oxo-2H-pyran-4-yl)-14,15-epoxyandrostan-16-yl acetate
- (3β,5β,15β,16β)-16-(Acetyloxy)-14,15-epoxy-3-hydroxybufa-20,22-dienolide
- 14,15-Epoxy-14H-cyclopenta[a]phenanthrene, bufa-20,22-dienolide deriv.
- 5β-Bufa-20,22-dienolide, 14,15β-epoxy-3β,16β-dihydroxy-, 16-acetate
- Bufa-20,22-dienolide, 16-(acetyloxy)-14,15-epoxy-3-hydroxy-, (3β,5β,15β,16β)-
- Cinobufagenin
- Cinobufagin
- Cinobufagine
- Cinobufogenin
- See more synonyms
- NSC 90325