CAS 473727-83-2

(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide

Description:

(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide, with CAS number 473727-83-2, is a complex organic compound characterized by its multi-functional structure. It features a benzamide core, which is modified with a hydroxy group and a dimethylamino group, contributing to its potential biological activity. The presence of a cyclobutene moiety with dioxo substituents adds to its reactivity and may influence its interaction with biological targets. Additionally, the incorporation of a furan ring suggests potential for aromatic interactions, which can be significant in drug design and molecular recognition. The stereochemistry indicated by the (R) configuration may affect the compound's pharmacological properties, including its binding affinity and selectivity for specific receptors or enzymes. Overall, this compound's intricate structure suggests it may have applications in medicinal chemistry, particularly in the development of therapeutics targeting specific biological pathways. Further studies would be necessary to elucidate its full range of properties and potential uses.

Formula: C₂₁H₂₃N₃O₅

Synonyms:

• (R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-2-yl)propylamino)-3
• (R)-2-hydroxy-N,N-diMethyl-3-((2-((1-(5-Methylfuran-2-yl)propyl)aMino)-3,4-dioxocyclobut-1-en-1-yl)aMino)benzaMide
• Sch 527123
• 2-Hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-(5-methyl-2-furanyl)propyl]amino]-3,4-dioxo-1-cyclobuten-1-yl
• (R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide
• SCH527123, Navarixin
• Benzamide, 2-hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-(5-methyl-2-furanyl)propyl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-
• 3-[[3-[(Dimethylamino)carbonyl]-2-hydroxyphenyl]amino]-4-[[(R)-1-(5-methylfuran-2-yl)propyl]amino]cyclobut-3-ene-1,2-dione

Navarixin

CAS: 473727-83-2

Navarixin

Purity: ≥98%

Molecular weight: 397.42g/mol

Ref: 54-BUP07662

Navarixin

CAS: 473727-83-2

Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophil

Formula: C₂₁H₂₃N₃O₅

Purity: 98% - 99.51%

Color and Shape: Solid

Molecular weight: 397.42

Ref: TM-T7130

Sch 527123

Controlled Product

CAS: 473727-83-2

Applications Sch 527123 is a potent CXCR2 antagonist. It can potentially inhibits human colon cancer liver metastasis.
References Varney, M. L., et al.: Cancer Lett 300, 180 (2011); Arshi, K., et al.: Front Immunol. 8, 464 (2017)

Formula: C₂₁H₂₃N₃O₅

Color and Shape: Neat

Molecular weight: 397.42

Ref: TR-S200200

CXCR2 Antagonist IV, Sch527123

CAS: 473727-83-2

CXCR2 Antagonist IV, Sch527123, is a small molecule antagonist, which is a synthetic chemical compound with high specificity and affinity for the CXCR2 receptor. This receptor is primarily sourced from the leukocyte population, playing a significant role in the inflammatory response and immune cell trafficking.

Formula: C₂₁H₂₃N₃O₅

Purity: Min. 95%

Molecular weight: 397.42 g/mol

Ref: 3D-YTA72783