CAS 474-25-9
:Chenodeoxycholic acid
Description:
Chenodeoxycholic acid (CDCA) is a bile acid that plays a crucial role in the digestion and absorption of dietary fats and fat-soluble vitamins in the intestine. It is a white to off-white crystalline powder that is soluble in water and organic solvents like ethanol and methanol. CDCA is synthesized in the liver from cholesterol and is a primary bile acid, meaning it is produced directly from cholesterol rather than being derived from other bile acids. Its chemical structure features a steroid nucleus with hydroxyl groups at specific positions, contributing to its amphipathic nature, which allows it to emulsify fats. CDCA is involved in the regulation of cholesterol metabolism and has been studied for its therapeutic potential in conditions such as gallstones and certain liver diseases. Additionally, it can influence the gut microbiome and has implications in metabolic health. As a naturally occurring substance, it is also used in various pharmaceutical formulations and dietary supplements.
Formula:C24H40O4
InChI:InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1
InChI key:InChIKey=RUDATBOHQWOJDD-BSWAIDMHSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@H]3O)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]
Synonyms:- (3Alpha,5Beta,7Alpha,8Xi,9Xi,14Xi)-3,7-Dihydroxycholan-24-Oic Acid
- (3Alpha,5Beta,7Alpha,8Xi,9Xi,14Xi)-3,7-Dihydroxycholan-24-Oicacid
- (3α,5β,7α)-3,7 Dihydroxycholan-24-oic acid
- (5Beta)-3,7-Dihydroxycholan-24-Oic Acid
- (5Beta)-3,7-Dihydroxycholan-24-Oicacid
- 17β-(1-Methyl-3-carboxypropyl)etiocholane-3α,7α-diol
- 3-Alpha,7-Alpha-Dihydroxy-5-Beta-Cholan-24-Oicacid
- 3alpha,7alpha-Dihydroxy-5beta-cholanic acid
- 3α,7α-Dihydroxy-5β-cholan-24-oic acid
- 3α,7α-Dihydroxy-5β-cholanic acid
- 3α,7α-Dihydroxy-5β-cholanoic acid
- 3α,7α-Dihydroxycholanic acid
- 5β-Cholan-24-oic acid, 3α,7α-dihydroxy-
- 5β-Cholanic acid, 3α,7α-dihydroxy-
- 7α-Hydroxylithocholic acid
- Acide chenodesoxycholique
- Acido Chenodeoxicholico
- Anthropodeoxycholic acid
- Anthropodesoxycholic acid
- Anthropododesoxycholic acid
- CDC
- CHOLANIC ACID, 3-α, 7-α-DIHYDROXY-5-β-
- Cdca
- Chendeoxycholicacid
- Chendol
- Chenic acid
- Chenix
- Chenocedon
- Chenocol
- Chenodeoxcholic acid
- Chenodesoxycholic acid
- Chenodesoxycholsaure
- Chenodex
- Chenodiol
- Chenofalk
- Chenossil
- Cholan-24-oic acid, 3,7-dihydroxy-, (3α,5β,7α)-
- Cholanorm
- Fluibil
- Gallodesoxycholic acid
- Hekbilin
- Kebilis
- See more synonyms
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Chenodeoxycholic Acid
CAS:Formula:C24H40O4Purity:>97.0%(GC)Color and Shape:White to Light yellow powder to crystalineMolecular weight:392.58CHENODEOXYCHOLIC ACID FOR SYSTEM SUITABILITY CRS
CAS:CHENODEOXYCHOLIC ACID FOR SYSTEM SUITABILITY CRSCHENODEOXYCHOLIC ACID FOR PEAK IDENTIFICATION CRS
CAS:CHENODEOXYCHOLIC ACID FOR PEAK IDENTIFICATION CRSChenodeoxycholic Acid MaxSpec® Standard
CAS:Formula:C24H40O4Purity:98%Color and Shape:SolidMolecular weight:392.5720Ref: IN-DA0039AV
5kgTo inquire5g20.00€10g28.00€25g31.00€50g53.00€100g64.00€250g119.00€500g164.00€1kg306.00€3kg911.00€10kg2,036.00€25kg5,081.00€50kg10,041.00€Chenodeoxycholic acid
CAS:Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!Formula:C24H40O4Purity:99.70% - 99.93%Color and Shape:White SolidMolecular weight:392.57Chenodeoxycholic acid, 98%
CAS:Formula:C24H40O4Purity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:392.57Chenodeoxycholic acid
CAS:Formula:C24H40O4Purity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:392.57Chenodeoxycholic Acid (Ursodeoxycholic Acid EP Impurity A)
CAS:Formula:C24H40O4Color and Shape:White To Off-White SolidMolecular weight:392.58Chenodeoxycholic acid, 97%, from chicken
CAS:Formula:C24H40O4Purity:≥ 97.0%Color and Shape:White or off-white powderMolecular weight:392.57Chenodeoxycholic acid
CAS:Purity:95.0%Color and Shape:Solid, Crystalline Powder or Needles or PowderMolecular weight:392.5799865722656Chenodeoxycholic acid
CAS:Formula:C24H40O4Purity:95%~99%Color and Shape:Cryst.Molecular weight:392.58Chenodeoxycholic acid
CAS:Chenodeoxycholic acidFormula:C24H40O4Purity:Loss on drying: 0.3%. (Typical Value in Batch COA)Color and Shape:White Solid-PowderMolecular weight:392.57199Chenodeoxycholic Acid
CAS:Controlled ProductImpurity Ursodeoxycholic Acid EP Impurity A
Applications Chenodeoxycholic Acid (Ursodeoxycholic Acid EP Impurity A) is a major bile acid in many vertebrates, occurring as the N-glycine and/or N-taurine conjugate. With other bile acids, forms mixed micelles with lecithin in bile which solubilize cholesterol and thus facilitates its excretion. Facilitates fat absorption in the small intestine by micellar solubilization of fatty acids and monoglycerides. Anticholelithogenic. Epimeric with Ursodiol.
References Danzinger, et al.: N. Engl. J. Med., 286, 1 (1972), Iser, J.H., et al.: Drugs, 21, 90 (1981), Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986),Formula:C24H40O4Color and Shape:NeatMolecular weight:392.57Chenodeoxycholic acid
CAS:Controlled ProductChenodeoxycholic acid is a human primary bile acid which is also found the bile of geese. Its C-7 epimer, Ursodeoxycholic acid is found in bearâs bile. Both bile acids are used for the treatment of gallstones, although Ursodeoxycholic acid has shown superior efficacy (bearâs bile extracts are also used in Chinese medicine).
Formula:C24H40O4Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:392.57 g/mol
