CAS 475-91-2

4,11-Dimethoxy-5-methyl-1,3-dioxolo[4,5-b]acridin-10(5H)-one

Description:

4,11-Dimethoxy-5-methyl-1,3-dioxolo[4,5-b]acridin-10(5H)-one, with CAS number 475-91-2, is a synthetic organic compound belonging to the acridine family. This compound features a complex polycyclic structure characterized by the presence of an acridine core, which is fused with a dioxole ring system. The presence of methoxy groups at the 4 and 11 positions contributes to its chemical reactivity and solubility properties, while the methyl group at the 5 position can influence its biological activity. The dioxolo moiety is known for its potential in various chemical reactions, including those involving electron transfer. This compound may exhibit fluorescence properties, making it of interest in photochemical applications. Additionally, due to its structural characteristics, it may possess biological activity, which has been explored in various research contexts, including its potential as a pharmaceutical agent. Overall, 4,11-Dimethoxy-5-methyl-1,3-dioxolo[4,5-b]acridin-10(5H)-one is a compound of interest in both synthetic chemistry and medicinal research.

Formula: C₁₇H₁₅NO₅

InChI: InChI=1/C17H15NO5/c1-18-10-7-5-4-6-9(10)13(19)11-12(18)15(21-3)17-16(14(11)20-2)22-8-23-17/h4-7H,8H2,1-3H3

InChI key: InChIKey=TZZNUDMEMFBPQI-UHFFFAOYSA-N

SMILES: O(C)C1=C2C(=C(OC)C3=C1OCO3)N(C)C=4C(C2=O)=CC=CC4

Synonyms:

• 1,3-Dioxolo(4,5-b)acridin-10(5H)-one, 4,11-dimethoxy-5-methyl-
• Brn 0335565
• Melicopidine
• Nsc 34757
• 4,11-Dimethoxy-5-methyl-1,3-dioxolo[4,5-b]acridin-10(5H)-one
• 4-27-00-06649 (Beilstein Handbook Reference)
• 4,11-Dimethoxy-5-methyl-1,3-dioxolo(4,5-b)acridin-10(5H)-one
• 4,11-dimethoxy-5-methyl-[1,3]dioxolo[4,5-b]acridin-10-one
• Melicopidene

Melicopidine

CAS: 475-91-2

Melicopidine is a synthetic alkaloid compound, which is derived through chemical synthesis mimicking natural alkaloids found in the Melicope genus. With a unique mechanism of inhibiting polyubiquitination processes, Melicopidine specifically targets the degradation pathways in Plasmodium species, the causative agents of malaria. This targeted interference disrupts protein turnover critical for the parasite's survival within erythrocytes.

Formula: C₁₇H₁₅NO₅

Purity: Min. 95%

Molecular weight: 313.3 g/mol

Ref: 3D-FM65850

Melicopidine

CAS: 475-91-2

Melicopidine (NSC 34757) is a DNA topoisomerase inhibitor and an acridone alkaloid found in the bark of the Medicosma subsessilis tree. It exhibits potential antitumor effects by binding to DNA or inhibiting the activity of related enzymes.

Formula: C₁₇H₁₅NO₅

Color and Shape: Solid

Molecular weight: 313.31

Ref: TM-TN11450