CAS 475489-15-7

Formula: C28H31N5O

InChI: InChI=1S/C28H31N5O/c29-27-26-25(22-9-6-10-24(15-22)34-18-20-7-2-1-3-8-20)17-33(28(26)31-19-30-27)23-13-21(14-23)16-32-11-4-5-12-32/h1-3,6-10,15,17,19,21,23H,4-5,11-14,16,18H2,(H2,29,30,31)

InChI key: LSFLAQVDISHMNB-UHFFFAOYSA-N

SMILES: C1CCN(C1)CC2CC(C2)N3C=C(C4=C(N=CN=C43)N)C5=CC(=CC=C5)OCC6=CC=CC=C6

cis-NVP-ADW742

CAS: 475489-15-7

NVP-ADW742 is an IGF-1R inhibitor with IC₅₀ of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.

Formula: C₂₈H₃₁N₅O

Color and Shape: Solid

Molecular weight: 453.59

Ref: TM-T2107