CAS 476-33-5

Homochelidonine

Description:

Homochelidonine is a naturally occurring alkaloid primarily derived from plants in the Papaveraceae family, particularly from the genus Chelidonium. It is characterized by its complex structure, which includes a tetracyclic framework typical of many isoquinoline alkaloids. This compound exhibits a range of biological activities, including analgesic, anti-inflammatory, and potential anticancer properties, making it of interest in pharmacological research. Homochelidonine is known to interact with various biological targets, influencing cellular pathways and exhibiting effects on the central nervous system. Its solubility properties can vary, and it is typically studied in organic solvents or as part of plant extracts. As with many alkaloids, caution is advised regarding its toxicity and side effects, which can arise from improper dosage or administration. Overall, homochelidonine represents a significant compound in the study of natural products and their therapeutic potential.

Formula: C₂₁H₂₃NO₅

InChI: InChI=1S/C21H23NO5/c1-22-9-14-12(4-5-16(24-2)21(14)25-3)19-15(23)6-11-7-17-18(27-10-26-17)8-13(11)20(19)22/h4-5,7-8,15,19-20,23H,6,9-10H2,1-3H3/t15-,19-,20+/m0/s1

InChI key: InChIKey=MADYLZJCRKUBIK-RYGJVYDSSA-N

SMILES: CN1[C@]2([C@@](C=3C(C1)=C(OC)C(OC)=CC3)([C@@H](O)CC=4C2=CC5=C(C4)OCO5)[H])[H]

Synonyms:

• (4BR-(4balpha,5beta,11balpha))-4b,5,6,11b,12,13-hexahydro-1,2-dimethoxy-12-methyl(1,3)benzodioxolo(5,6-c)phenanthridin-5-ol
• (4bR,5S,11bS)-1,2-dimethoxy-12-methyl-4b,5,6,11b,12,13-hexahydro[1,3]benzodioxolo[5,6-c]phenanthridin-5-ol
• (4bR,5S,11bS)-4b,5,6,11b,12,13-Hexahydro-1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-5-ol
• [1,3]Benzodioxolo[5,6-c]phenanthridin-5-ol, 4b,5,6,11b,12,13-hexahydro-1,2-dimethoxy-12-methyl-, (4bR,5S,11bS)-
• [1,3]Benzodioxolo[5,6-c]phenanthridin-5-ol, 4b,5,6,11b,12,13-hexahydro-1,2-dimethoxy-12-methyl-, [4bR-(4bα,5β,11bα)]-
• α-Homochelidonine
• Homochelidonine

α-Homochelidonine

CAS: 476-33-5

α-Homochelidonine is a natural isoquinoline alkaloid, which is derived from the plant Chelidonium majus, commonly known as greater celandine. This compound exhibits significant pharmacological activity, primarily through its ability to interact with various cellular targets. Its mode of action involves the inhibition of certain cell signaling pathways, which can lead to effects such as apoptosis and modulation of ion channel activities.

Formula: C₂₁H₂₃NO₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 369.41 g/mol

Ref: 3D-FH65799