CAS 477227-33-1

Acyl 12:0 NBD pc

CAS: 477227-33-1

Acyl 12:0 NBD pc is a spla2 activity inhibitor that stabilizes membranes, preventing their fission. It also inhibits the enzyme sphingomyelinase, which catalyzes the hydrolysis of sphingomyelin to form phosphatidylcholine. Acyl 12:0 NBD pc mimics glycerophospholipids by binding to the lipid bilayer and stabilizing it, preventing its collapse. This compound has been shown to inhibit the production of secretory phospholipase A2 (sPLA2) and phosphatidylcholine by cells in culture.

Formula: C₄₂H₇₄N₅O₁₁P

Purity: Min. 95%

Molecular weight: 856.04 g/mol

Ref: 3D-CUA22733