CAS 47739-98-0

Clocapramine

Description:

Clocapramine, with the CAS number 47739-98-0, is a chemical compound that belongs to the class of phenothiazines, which are primarily known for their use in psychiatric medications. It exhibits properties that suggest it may function as an antipsychotic agent, although its specific therapeutic applications and efficacy are less well-documented compared to more widely known phenothiazines. Clocapramine's molecular structure includes a phenothiazine core, which contributes to its pharmacological activity. The compound is characterized by its ability to interact with various neurotransmitter systems, particularly those involving dopamine and serotonin, which are crucial in mood regulation and psychotic disorders. Additionally, like many compounds in its class, clocapramine may exhibit side effects typical of antipsychotic medications, including sedation and potential extrapyramidal symptoms. Its solubility, stability, and specific interactions with biological systems are important factors in its pharmacological profile, although detailed studies are necessary to fully understand its characteristics and potential clinical applications.

Formula: C₂₈H₃₇ClN₄O

InChI: InChI=1/C28H37ClN4O/c29-24-12-11-23-10-9-22-7-2-3-8-25(22)33(26(23)21-24)18-6-15-31-19-13-28(14-20-31,27(30)34)32-16-4-1-5-17-32/h2-3,7-8,11-12,21H,1,4-6,9-10,13-20H2,(H2,30,34)

InChI key: InChIKey=QAZKXHSIKKNOHH-UHFFFAOYSA-N

SMILES: C(N)(=O)C1(CCN(CCCN2C=3C(CCC=4C2=CC=CC4)=CC=C(Cl)C3)CC1)N5CCCCC5

Synonyms:

• 1'-[3-(3-Chloro-10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl][1,4'-bipiperidine]-4'-carboxamide
• 1'-[3-(3-Chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]-1,4'-bipiperidine-4'-carboxamide
• 3-Chloro-5-[3-(4-piperidino-4-carbamoylpiperidino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine
• 3-Chlorocarpipramine
• 47739-98-0
• 5H-Dibenz[b,f]azepine, [1,4′-bipiperidine]-4′-carboxamide deriv.
• Clocarpramine
• [1,4'-bipiperidine]-4'-carboxamide, 1'-[3-(3-chloro-10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]-
• 65016-29-7 (Di-hydrochloride monohydrate)
• 1-[3-(3-Chloro-10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]-4-piperidino-4-piperidinecarboxamide
• Clocapraminum [inn-latin]
• Clocapramina [inn-spanish]
• Clocapramina
• 28058-62-0 (Di-hydrochloride)

Clocapramine

Controlled Product

CAS: 47739-98-0

Applications Clocapramine is an anti-psychotic drug.
References Ishigooka, J., et al.: Psychopharmacology 97, 303-308 (1989)

Formula: C₂₈H₃₇ClN₄O

Color and Shape: Neat

Molecular weight: 481.07

Ref: TR-C853690