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CAS 4779-31-1

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Z-Asp-OBzl

Description:
Z-Asp-OBzl, also known as benzyloxycarbonyl-L-aspartic acid, is a derivative of aspartic acid where the amino group is protected by a benzyloxycarbonyl (Z) group. This compound is characterized by its ability to serve as a building block in peptide synthesis, particularly in the formation of peptides where selective protection of functional groups is necessary. The Z group provides stability and protection during synthetic procedures, allowing for the selective deprotection of the amino acid when required. Z-Asp-OBzl is typically a white to off-white crystalline solid, soluble in organic solvents like methanol and dimethyl sulfoxide, but less soluble in water. Its structure includes a carboxylic acid group, an amine group, and a benzyl ester, contributing to its reactivity and utility in organic synthesis. The compound is often used in research and pharmaceutical applications, particularly in the development of peptide-based drugs and in studies involving amino acid derivatives. Proper handling and storage conditions are essential to maintain its stability and integrity.
Formula:C19H19NO6
InChI:InChI=1/C19H19NO6/c21-17(22)11-16(18(23)25-12-14-7-3-1-4-8-14)20-19(24)26-13-15-9-5-2-6-10-15/h1-10,16H,11-13H2,(H,20,24)(H,21,22)/t16-/m0/s1
SMILES:c1ccc(cc1)COC(=O)[C@H](CC(=O)O)N=C(O)OCc1ccccc1
Synonyms:
  • 4-(Benzyloxy)-3-{[(Benzyloxy)Carbonyl]Amino}-4-Oxobutanoic Acid (Non-Preferred Name)
  • (3S)-4-(benzyloxy)-3-{[(benzyloxy)carbonyl]amino}-4-oxobutanoic acid (non-preferred name)
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