CAS 478-43-3

Rhein

Description:

Rhein, with the CAS number 478-43-3, is a naturally occurring anthraquinone compound primarily found in various plants, particularly in the rhubarb species. It is characterized by its yellow crystalline appearance and is known for its potential medicinal properties, including anti-inflammatory, antioxidant, and laxative effects. Rhein exhibits solubility in organic solvents such as ethanol and dimethyl sulfoxide, but it is less soluble in water. The compound has garnered interest in pharmacological research due to its ability to modulate various biological pathways, including those involved in cell signaling and apoptosis. Additionally, Rhein has been studied for its potential applications in treating conditions such as diabetes and certain types of cancer. Its chemical structure features multiple hydroxyl groups, contributing to its reactivity and biological activity. As with many natural compounds, the safety and efficacy of Rhein in therapeutic contexts require further investigation through clinical studies.

Formula: C₁₅H₈O₆

InChI: InChI=1S/C15H8O6/c16-9-3-1-2-7-11(9)14(19)12-8(13(7)18)4-6(15(20)21)5-10(12)17/h1-5,16-17H,(H,20,21)

InChI key: InChIKey=FCDLCPWAQCPTKC-UHFFFAOYSA-N

SMILES: O=C1C=2C(C(=O)C=3C1=C(O)C=CC3)=CC(C(O)=O)=CC2O

Synonyms:

• 1,8-Dihydroxy-3-Carboxy anthraquinone
• 1,8-Dihydroxy-3-carboxyanthraquinone
• 1,8-Dihydroxyanthraquinone-3-carboxylic acid
• 2-Anthracenecarboxylic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-
• 2-Anthraquinonecarboxylic acid, 4,5-dihydroxy-
• 2-Anthroic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-
• 4,5-Dihydroxy-2-anthraquinonecarboxylic acid
• 4,5-Dihydroxy-9,10-Dioxo-9,10-Dihydroanthracene-2-Carboxylate
• 4,5-Dihydroxy-9,10-Dioxo-9,10-Dihydroanthracene-2-Carboxylic Acid
• 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid
• Cassic acid
• Chrysazin-3-carboxylic acid
• Monorhein
• NSC 38629
• Rheic acid
• Rheinic acid

4,5-Dihydroxyanthraquinone-2-carboxylic Acid

CAS: 478-43-3

Formula: C₁₅H₈O₆

Purity: >95.0%(T)(HPLC)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 284.22

Ref: 3B-D3986

Rhein, 97%

CAS: 478-43-3

Rhein is used to inhibit growth factor beta-1 induced plasminogen activator inhibitor-1 in endothelial cells. It acts as an antibacterial agent against Staphylococcus aureus. It is also used as a laxative. Further, it is employed as a pharmaceutical intermediate. This Thermo Scientific Chemicals bra

Formula: C₁₅H₈O₆

Purity: 97%

Molecular weight: 284.22

Ref: 02-H60902

Rhein

CAS: 478-43-3

Rhein analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₅H₈O₆

Purity: (HPLC) ≥99%

Color and Shape: Powder

Molecular weight: 284.23

Ref: 11-0455S

RHEIN CRS

CAS: 478-43-3

RHEIN CRS

Ref: 41-Y0002159

Rhein

CAS: 478-43-3

Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.

Formula: C₁₅H₈O₆

Purity: 99.04%

Color and Shape: Physical Description Yellow Needles (From Methanol) Or Yellow-Brown Powder (Ntp 1992)

Molecular weight: 284.22

Ref: TM-T2997

1,8-DIHYDROXY-3-CARBOXYANTHRAQUINONE

CAS: 478-43-3

Formula: C₁₅H₈O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 284.2204

Ref: IN-DA0037FB

Rhein-13C6 (1,2,3,4,4a,9a-13C6)

CAS: 478-43-3

Formula: C₉₁₃C₆H₈O₆

Molecular weight: 290.18

Ref: 4Z-R-2818

Rhein

CAS: 478-43-3

Formula: C₁₅H₈O₆

Color and Shape: Yellow Solid

Molecular weight: 284.22

Ref: 4Z-R-281

Rhein

CAS: 478-43-3

Rhein

Purity: 98%

Molecular weight: 284.22g/mol

Ref: 54-OR1029292

Rhein

CAS: 478-43-3

Formula: C₁₅H₈O₆

Purity: ≥ 98.0%

Color and Shape: Yellow to orange powder

Molecular weight: 284.22

Ref: 7W-GP8350

Rhein

CAS: 478-43-3

Rhein

Purity: ≥98%

Molecular weight: 284.22g/mol

Ref: 54-BUP16879

Rhein-13C4

CAS: 478-43-3

Formula: C₁₁₁₃C₄H₈O₆

Color and Shape: Orange Solid

Molecular weight: 288.19

Ref: 4Z-R-282

Rhein

CAS: 478-43-3

Rhein, an anthraquinone compound isolated from rhubarb, has been proved effective in treatment of experimental diabetic nephropathy (DN), one of the mechanism is the Inhibition of the hexosamine pathway.

Formula: C₁₅H₈O₆

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 284.223

Ref: BP-BP1208

Rhein

CAS: 478-43-3

Quinone

Formula: C₁₅H₈O₆

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 284.23

Ref: 5G-89385

Rhein

CAS: 478-43-3

Impurity Diacerein Impurity C
Stability Hygroscopic
Applications Found in the free state and as glucoside in Rheum spp, Polygonaceae (rhubarb) and in Senna leaves.A potential antioxidant resource: endophytic fungi from medicinal plants . Diacerein Impurity C
References Wanitschke, Pharmacology, 20, Suppl. 1, 21 (1980), Raimondi, L., et al.: Pharmacol. Res. Commun., 14, 103 (1982), Franchi-Micheli, S., et al.: J. Pharm. Pharmacol., 35, 262 (1983),

Formula: C₁₅H₈O₆

Color and Shape: Neat

Molecular weight: 284.22

Ref: TR-R318500

Diacerein EP Impurity C

CAS: 478-43-3

Formula: C₁₅H₈O₆

Molecular weight: 284.2

Ref: ST-EA-CP-D19003

Rhein

CAS: 478-43-3

Rhein is an anthraquinone compound, which is derived from the plant rhubarb (Rheum species) with a range of unique biological activities. It functions primarily by inhibiting the activity of various enzymes and pathways involved in inflammation, oxidative stress, and cellular proliferation. Rhein is known for its ability to modulate the production of cytokines and other inflammatory mediators, offering potential therapeutic benefits in the treatment of inflammatory diseases.

Formula: C₁₅H₈O₆

Purity: Min. 98.0 Area-%

Color and Shape: Powder

Molecular weight: 284.22 g/mol

Ref: 3D-FR27724

1,8-Dihydroxy-3-carboxyanthraquinone

CAS: 478-43-3

Formula: C₁₅H₈O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 284.223

Ref: 10-F049599