CAS 4784-40-1

Oxomemazine hydrochloride

Description:

Oxomemazine hydrochloride is an antihistamine and sedative medication primarily used for its antiallergic properties. It belongs to the phenothiazine class of compounds and is characterized by its ability to block histamine H1 receptors, which helps alleviate allergic symptoms. The substance is typically administered in the form of its hydrochloride salt, enhancing its solubility and bioavailability. Oxomemazine exhibits sedative effects, making it useful in treating conditions such as insomnia and anxiety, particularly in pediatric populations. It is also noted for its potential to cause drowsiness, which is a common side effect associated with antihistamines. The compound has a relatively low toxicity profile but may interact with other central nervous system depressants, necessitating caution in concurrent use. As with many medications, it is essential to adhere to prescribed dosages to minimize adverse effects and ensure therapeutic efficacy. Overall, oxomemazine hydrochloride is a valuable agent in managing allergic reactions and related conditions, with a well-established profile in clinical use.

Formula: C₁₈H₂₃ClN₂O₂S

InChI: InChI=1/C18H22N2O2S.ClH/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)23(21,22)18-11-7-5-9-16(18)20;/h4-11,14H,12-13H2,1-3H3;1H

InChI key: InChIKey=NPMMOYKGIWLASW-UHFFFAOYSA-N

SMILES: C(C(CN(C)C)C)N1C=2C(S(=O)(=O)C=3C1=CC=CC3)=CC=CC2.Cl

Synonyms:

• 10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-, 5,5-dioxide, hydrochloride (1:1)
• 10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-, 5,5-dioxide, monohydrochloride
• 3-(5,5-dioxido-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine hydrochloride
• N,N,beta-Trimethyl-10H-phenothiazine-10-propylamine 5,5-dioxide monohydrochloride
• Oxomemazine hydrochloride
• Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]-, 5,5-dioxide, monohydrochloride
• N,N,β-Trimethyl-[10H]-phenothiazine-10-propanamine 5,5-dioxide hydrochloride
• Oxomemazine·hydrochloric acid
• 10-(3-(dimethylamino)-2-methylpropyl)-10H-phenothiazine 5,5-dioxide hydrochloride
• Ao Suoma hydrochloride

Oxomemazine hydrochloride

CAS: 4784-40-1

Oxomemazine hydrochloride

Formula: C₁₈H₂₃ClN₂O₂S

Purity: 95%

Molecular weight: 366.91

Ref: 54-OR1121404

Oxomemazine HCl

CAS: 4784-40-1

Formula: C₁₈H₂₂N₂O₂S·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 330.45 36.46

Ref: 4Z-O-131

Oxomemazine hydrochloride

CAS: 4784-40-1

Formula: C₁₈H₂₃ClN₂O₂S

Purity: 95%

Molecular weight: 366.9054

Ref: IN-DA00DDSP

Oxomemazine hydrochloride

CAS: 4784-40-1

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Formula: C₁₈H₂₂N₂O₂S•HCl

Purity: Min. 95%

Molecular weight: 366.91 g/mol

Ref: 3D-FO184347

Oxomemazine Hydrochloride

CAS: 4784-40-1

Formula: C₁₈H₂₂N₂O₂SHCl

Molecular weight: 330.4 : 36.46

Ref: ST-EA-CP-O32002

Oxomemazine hydrochloride

CAS: 4784-40-1

Oxomemazine hydrochloride is a phenothiazine-based histamine H1-receptor blocker with notable antimuscarinic activity. As a selective antagonist of the muscarinic M1 receptor, Oxomemazine demonstrates a 20-fold difference in affinity at high (histamine H1-receptor=84 nM, M1 receptor) and low (histamine H1-receptor=1.65 μM, M2 receptor) affinity sites. It serves as an antihistamine and anticholinergic agent used in cough-related research studies.

Formula: C₁₈H₂₃ClN₂O₂S

Molecular weight: 366.905

Ref: TM-T206349