CAS 479-18-5

diprophylline

Description:

Diprophylline is a xanthine derivative that exhibits bronchodilator properties, making it useful in the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It is characterized by its ability to relax bronchial smooth muscle, thereby improving airflow and alleviating symptoms of bronchospasm. Chemically, diprophylline is known for its relatively low toxicity and good tolerability in patients. It has a moderate solubility in water and is often administered in oral form. The substance acts by inhibiting phosphodiesterase, leading to increased levels of cyclic AMP, which contributes to its bronchodilatory effects. Additionally, diprophylline may have mild diuretic properties and can influence cardiac function. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion, which are important for determining dosing regimens. Overall, diprophylline is a valuable therapeutic agent in respiratory medicine, with a profile that supports its use in managing airway obstruction.

Formula: C₁₀H₁₄N₄O₄

InChI: InChI=1/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3/t6-/m1/s1

InChI key: InChIKey=KSCFJBIXMNOVSH-UHFFFAOYSA-N

SMILES: C(C(CO)O)N1C2=C(N(C)C(=O)N(C)C2=O)N=C1

Synonyms:

• (Rac)-diprophylline
• 1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-
• 7-(2,3-Dihydroxypropyl)-1,3-dimethylxanthine
• 7-(2,3-Dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
• 7-(2,3-Dihydroxypropyl)theophylline
• 7-(β,γ-Dihydroxypropyl)theophylline
• 7-[(2R)-2,3-dihydroxypropyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
• 7-[(2S)-2,3-dihydroxypropyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
• AFI-phyllin
• Airet
• Aristophyllin
• Asthmolysin
• Astmamasit
• Astmophysine
• Astrophyllin
• Athmolysin
• Chlordehydromethyl Testosterone Acetate
• Circain
• Circair
• Cor-Theophyllin
• Cor-Theophylline
• Coronal
• Coronarin
• Corphyllin
• Dilor
• Diphyllin
• Diphylline
• Diphylline (pharmaceutical)
• Diprofilina
• Diprofillin
• Diprophyllin
• Dyphylline
• Emfaseem
• Glyfyllin
• Glyphyllin
• Glyphylline
• Hidroxiteofillina
• Hiphyllin
• Hyphylline
• Isophyllen
• Lufyllin
• Lufyllin-EPG
• Neo-Vasophylline
• Neophyl
• Neophyllin
• Neophyllin M
• Neophylline
• Neostenovasan
• Neothyllin
• Neothylline
• Neotilina
• Neufil
• Neutrafil
• Neutrafillina
• Neutraphyllin
• Neutraphylline
• Neutroxantina
• Nsc 14305
• Nsc 40844
• Prophyllen
• Propyphyllin
• Protheophylline
• Purifilin
• Silbephyllin
• Silbephylline
• Solufilin
• Solufyllin
• Soluphyllin
• Synthophylline
• Tefilan
• Teofen
• Theal
• Theal ampules
• Thefulan
• Thefylan
• Theophylline, 7-(2,3-dihydroxypropyl)-
• 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1h-purine-6-dione
• 7-(BETA,GAMMA-DIHYDROXYPROPYL)-THEOPHYLLINE
• TIMTEC-BB SBB003125
• 1,3-Dimethyl-7-(2,3-dihydroxypropyl)xanthine
• (1,2-Dihydroxy-3-propyl)thiophyllin
• 7-(2,3-Dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
• DIPROPYHYLLIN
• 7-(2,3-dihydroxypropyl)-1,3-dimethyl-purine-2,6-dione
• DIPROPHYLLINE
• 7(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1h-purine-6-dione

7-(2,3-Dihydroxypropyl)theophylline

CAS: 479-18-5

Formula: C₁₀H₁₄N₄O₄

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 254.25

Ref: 3B-D3600

Dyphylline

CAS: 479-18-5

An adenosine receptor antagonist, phosphodiesterase inhibitor and vasodilator

Formula: C₁₀H₁₄N₄O₄

Molecular weight: 254.24

Ref: 02-J63167

DIPROPHYLLINE CRS

CAS: 479-18-5

DIPROPHYLLINE CRS

Formula: C₁₀H₁₄N₄O₄

Color and Shape: Crystalline Powder. White. Whitish. Powder.

Molecular weight: 254.2426

Ref: 41-D2800000

Dyphylline

CAS: 479-18-5

Theophylline and aminophylline (excluding fenetylline) and their derivatives, salts thereof, not elsewhere specified or included

Formula: C₁₀H₁₄N₄O₄

Color and Shape: White Powder

Molecular weight: 254.1015

Ref: 45-1231502

Diphylline

CAS: 479-18-5

Formula: C₁₀H₁₄N₄O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 254.2426

Ref: IN-DA006YEZ

Diphylline

CAS: 479-18-5

Diphylline is a bronchodilator with mild vasodilator and diuretic properties, used for asthma, bronchitis, and emphysema.

Formula: C₁₀H₁₄N₄O₄

Purity: 98.54%

Color and Shape: Crystals From Alcohol Solid

Molecular weight: 254.24

Ref: TM-T0892

Diprophylline

CAS: 479-18-5

Diprophylline

Purity: 98%

Molecular weight: 254.24g/mol

Ref: 54-OR1026964

Diphylline

CAS: 479-18-5

Diphylline

Purity: ≥98%

Molecular weight: 254.24g/mol

Ref: 54-BUP18802

Diprophylline (7-(2,3-Dihydroxypropyl)theophylline)

CAS: 479-18-5

Formula: C₁₀H₁₄N₄O₄

Molecular weight: 254.24

Ref: 7W-GK4515

Diprophylline

Controlled Product

CAS: 479-18-5

Formula: C₁₀H₁₄N₄O₄

Color and Shape: Neat

Molecular weight: 254.24

Ref: 04-C12935000

Diprophylline

Controlled Product

CAS: 479-18-5

Formula: C₁₀H₁₄N₄O₄

Color and Shape: Neat

Molecular weight: 254.24

Ref: 86-MM1191.00

Dyphylline (Diprophylline)

CAS: 479-18-5

Formula: C₁₀H₁₄N₄O₄

Molecular weight: 254.25

Ref: 4Z-D-112001

Dyphylline

Controlled Product

CAS: 479-18-5

Applications Bronchodilator.
References Reitz, C., et al.: Eur. J. Pharm. Sci., 35, 335 (2008), Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010),

Formula: C₁₀H₁₄N₄O₄

Color and Shape: White To Off-White

Molecular weight: 254.24

Ref: TR-D826500

Dyphylline

Controlled Product

CAS: 479-18-5

Dyphylline is a pharmaceutical drug that is used to treat asthma and chronic pulmonary obstructive disease. It is also used as a bronchodilator to relieve the symptoms of asthma and other respiratory disorders by relaxing the air passages. Dyphylline works by increasing the availability of oxygen to the lungs, which helps to relax the muscles around the airways. This leads to an increase in airflow into and out of the lungs. The drug inhibits bacterial growth by inhibiting chemotactic activity and hydroxyl group-dependent reactions, including protein synthesis. It also has potent antimicrobial activity against a wide range of microorganisms, including some strains of bacteria that are resistant to erythromycin and metoprolol succinate, which are two common antibiotics for treating respiratory infections. Dyphylline has been shown to have no effect on human serum albumin levels or on renal function (e.g., glomerular filtration rate).

Formula: C₁₀H₁₄N₄O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 254.24 g/mol

Ref: 3D-FD22634

7-(2,3-Dihydroxypropyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione

CAS: 479-18-5

Formula: C₁₀H₁₄N₄O₄

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 254.246

Ref: 10-F464564

Dyphylline

CAS: 479-18-5

Formula: C₁₀H₁₄N₄O₄

Molecular weight: 254.25

Ref: ST-EA-CP-T59034