CAS 479-18-5
:diprophylline
Description:
Diprophylline is a xanthine derivative that exhibits bronchodilator properties, making it useful in the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It is characterized by its ability to relax bronchial smooth muscle, thereby improving airflow and alleviating symptoms of bronchospasm. Chemically, diprophylline is known for its relatively low toxicity and good tolerability in patients. It has a moderate solubility in water and is often administered in oral form. The substance acts by inhibiting phosphodiesterase, leading to increased levels of cyclic AMP, which contributes to its bronchodilatory effects. Additionally, diprophylline may have mild diuretic properties and can influence cardiac function. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion, which are important for determining dosing regimens. Overall, diprophylline is a valuable therapeutic agent in respiratory medicine, with a profile that supports its use in managing airway obstruction.
Formula:C10H14N4O4
InChI:InChI=1/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3/t6-/m1/s1
InChI key:InChIKey=KSCFJBIXMNOVSH-UHFFFAOYSA-N
SMILES:C(C(CO)O)N1C2=C(N(C)C(=O)N(C)C2=O)N=C1
Synonyms:- (Rac)-diprophylline
- 1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-
- 7-(2,3-Dihydroxypropyl)-1,3-dimethylxanthine
- 7-(2,3-Dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
- 7-(2,3-Dihydroxypropyl)theophylline
- 7-(β,γ-Dihydroxypropyl)theophylline
- 7-[(2R)-2,3-dihydroxypropyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
- 7-[(2S)-2,3-dihydroxypropyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
- AFI-phyllin
- Airet
- Aristophyllin
- Asthmolysin
- Astmamasit
- Astmophysine
- Astrophyllin
- Athmolysin
- Chlordehydromethyl Testosterone Acetate
- Circain
- Circair
- Cor-Theophyllin
- Cor-Theophylline
- Coronal
- Coronarin
- Corphyllin
- Dilor
- Diphyllin
- Diphylline
- Diphylline (pharmaceutical)
- Diprofilina
- Diprofillin
- Diprophyllin
- Dyphylline
- Emfaseem
- Glyfyllin
- Glyphyllin
- Glyphylline
- Hidroxiteofillina
- Hiphyllin
- Hyphylline
- Isophyllen
- Lufyllin
- Lufyllin-EPG
- Neo-Vasophylline
- Neophyl
- Neophyllin
- Neophyllin M
- Neophylline
- Neostenovasan
- Neothyllin
- Neothylline
- Neotilina
- Neufil
- Neutrafil
- Neutrafillina
- Neutraphyllin
- Neutraphylline
- Neutroxantina
- Nsc 14305
- Nsc 40844
- Prophyllen
- Propyphyllin
- Protheophylline
- Purifilin
- Silbephyllin
- Silbephylline
- Solufilin
- Solufyllin
- Soluphyllin
- Synthophylline
- Tefilan
- Teofen
- Theal
- Theal ampules
- Thefulan
- Thefylan
- Theophylline, 7-(2,3-dihydroxypropyl)-
- 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1h-purine-6-dione
- 7-(BETA,GAMMA-DIHYDROXYPROPYL)-THEOPHYLLINE
- TIMTEC-BB SBB003125
- 1,3-Dimethyl-7-(2,3-dihydroxypropyl)xanthine
- (1,2-Dihydroxy-3-propyl)thiophyllin
- 7-(2,3-Dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
- DIPROPYHYLLIN
- 7-(2,3-dihydroxypropyl)-1,3-dimethyl-purine-2,6-dione
- DIPROPHYLLINE
- 7(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1h-purine-6-dione
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7-(2,3-Dihydroxypropyl)theophylline
CAS:Formula:C10H14N4O4Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:254.25Dyphylline
CAS:An adenosine receptor antagonist, phosphodiesterase inhibitor and vasodilatorFormula:C10H14N4O4Color and Shape:White, Powder or crystalline powderMolecular weight:254.25DIPROPHYLLINE CRS
CAS:DIPROPHYLLINE CRSFormula:C10H14N4O4Color and Shape:Crystalline Powder. White. Whitish. Powder.Molecular weight:254.2426Dyphylline
CAS:Theophylline and aminophylline (excluding fenetylline) and their derivatives, salts thereof, not elsewhere specified or includedFormula:C10H14N4O4Color and Shape:White PowderMolecular weight:254.1015Diphylline
CAS:Diphylline is a bronchodilator with mild vasodilator and diuretic properties, used for asthma, bronchitis, and emphysema.Formula:C10H14N4O4Purity:98.54%Color and Shape:SolidMolecular weight:254.24267-(2,3-Dihydroxypropyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione
CAS:Formula:C10H14N4O4Purity:98%Color and Shape:SolidMolecular weight:254.2426Dyphylline
CAS:Controlled ProductApplications Bronchodilator.
References Reitz, C., et al.: Eur. J. Pharm. Sci., 35, 335 (2008), Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010),Formula:C10H14N4O4Color and Shape:NeatMolecular weight:254.247-(2,3-Dihydroxypropyl)theophylline
CAS:7-(2,3-Dihydroxypropyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dioneFormula:C10H14N4O4Purity:98%Molecular weight:254.247-(2,3-Dihydroxypropyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione
CAS:Formula:C10H14N4O4Purity:95.0%Color and Shape:SolidMolecular weight:254.246Dyphylline
CAS:Controlled ProductDyphylline is a pharmaceutical drug that is used to treat asthma and chronic pulmonary obstructive disease. It is also used as a bronchodilator to relieve the symptoms of asthma and other respiratory disorders by relaxing the air passages. Dyphylline works by increasing the availability of oxygen to the lungs, which helps to relax the muscles around the airways. This leads to an increase in airflow into and out of the lungs. The drug inhibits bacterial growth by inhibiting chemotactic activity and hydroxyl group-dependent reactions, including protein synthesis. It also has potent antimicrobial activity against a wide range of microorganisms, including some strains of bacteria that are resistant to erythromycin and metoprolol succinate, which are two common antibiotics for treating respiratory infections. Dyphylline has been shown to have no effect on human serum albumin levels or on renal function (e.g., glomerular filtration rate).
Formula:C10H14N4O4Purity:Min. 95%Color and Shape:PowderMolecular weight:254.24 g/molRef: 3D-FD22634
Discontinued product
