CAS 479-91-4

Casticin

Description:

Casticin, with the CAS number 479-91-4, is a flavonoid compound primarily found in various plants, particularly in the genus Vitex, such as Vitex agnus-castus (chaste tree). It is characterized by its yellow crystalline appearance and is known for its potential pharmacological properties, including anti-inflammatory, antioxidant, and neuroprotective effects. Casticin exhibits a range of biological activities, which have garnered interest in the fields of herbal medicine and pharmacology. Its mechanism of action may involve modulation of various signaling pathways and interactions with specific receptors. Additionally, casticin has been studied for its potential effects on hormonal regulation, particularly in relation to reproductive health. The compound is soluble in organic solvents but has limited solubility in water, which is a common characteristic of many flavonoids. Overall, casticin represents a significant area of research due to its diverse biological activities and potential therapeutic applications.

Formula: C₁₉H₁₈O₈

InChI: InChI=1S/C19H18O8/c1-23-11-6-5-9(7-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3

InChI key: InChIKey=PJQLSMYMOKWUJG-UHFFFAOYSA-N

SMILES: O=C1C=2C(OC(=C1OC)C3=CC(O)=C(OC)C=C3)=CC(OC)=C(OC)C2O

Synonyms:

• 3,6,7,4′-Tetra-O-methyl-5,3′-dihydroxyflavone
• 3,6,7,4′-Tetra-O-methylquercetagetin
• 4H-1-benzopyran-4-one, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-
• 5,12-Dihydroxy-2,6,7,13-tetramethoxyflavone
• 5,3′-Dihydroxy-3,6,7,4′-tetramethoxyflavone
• 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one
• 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-chromen-4-on
• 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-chromen-4-one
• Casticine
• Flavone, 3′,5-dihydroxy-3,4′,6,7-tetramethoxy-
• Quercetagetin 3,6,7,4′-tetramethyl ether
• Vitexcarpin
• Vitexicarpin

Casticin

CAS: 479-91-4

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Formula: C₁₉H₁₈O₈

Color and Shape: Light Yellow Powder

Molecular weight: 374.10017

Ref: 45-1096779

Casticin

CAS: 479-91-4

Casticin

Formula: C₁₉H₁₈O₈

Purity: ≥95%

Molecular weight: 374.34

Ref: 54-BUP03345

Casticin

CAS: 479-91-4

Formula: C₁₉H₁₈O₈

Purity: ≥ 98.0%

Color and Shape: White to yellow powder

Molecular weight: 374.34

Ref: 7W-GL8513

Casticin

CAS: 479-91-4

Casticin

Formula: C₁₉H₁₈O₈

Purity: 98%

Molecular weight: 374.34

Ref: 54-OR1023248

Vitexicarpin

CAS: 479-91-4

Formula: C₁₉H₁₈O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 374.3414

Ref: IN-DA00DE0H

Casticin

CAS: 479-91-4

Vitexicarpin has shown antitumor, cytotoxicity, anti-inflammatory, analgesic and immunoregulatory properties.Vitexicarpin can act as a novel angiogenesis inhibitor, it exerts good antiangiogenic effects by inhibiting vascular-endothelial-growth-factor-(VEGF-) induced endothelial cell proliferation, migration, and capillary-like tube formation on matrigel in a dose-dependent manner. It can significantly reduce vascular inflammation, through inhibition of ROS-NF-κB pathway in vascular endothelial cells.

Formula: C₁₉H₁₈O₈

Purity: 95%~99%

Molecular weight: 374.345

Ref: BP-BP0320

Casticin

CAS: 479-91-4

Casticin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₉H₁₈O₈

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 374.35

Ref: 11-1336S

Casticin (Standard)

CAS: 479-91-4

Casticin (Standard) is a reference standard for research and analysis in studies involving Casticin. 1. Casticin (Vitexicarpin) can significantly reduce vascular inflammation, through inhibition of ROS-NF-κB pathway in vascular endothelial cells. 2. Casticin may become a potential leading drug in the therapy of prostate carcinoma.

Formula: C₁₉H₁₈O₈

Molecular weight: 374.3414

Ref: TM-TMSM-2520

Casticin

Controlled Product

CAS: 479-91-4

Applications Casticin is a biological compound known to induce human glioma cell death through an apoptotic mechanism and disruption of the mitotic cycle.
References Liu, E. et al.: (Cell. Phys. Biochem., 31, 805 (2013); Zhu, J. et al.: J. Agri. Food Chem., 55, 2438 (2007);

Formula: C₁₉H₁₈O₈

Color and Shape: Neat

Molecular weight: 374.34

Ref: TR-C186000

Casticin

CAS: 479-91-4

Casticin combats vascular inflammation by blocking ROS-NF-κB and could lead in prostate cancer treatment.

Formula: C₁₉H₁₈O₈

Purity: 99.59% - ≥95%

Color and Shape: Solid

Molecular weight: 374.3414

Ref: TM-T6S1373

Vitexicarpin

CAS: 479-91-4

5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-chromen-4-one

Formula: C₁₉H₁₈O₈

Purity: 98%

Molecular weight: 374.34

Ref: IN-DG120161

Casticin

CAS: 479-91-4

Oxygen-heterocyclic compound

Formula: C₁₉H₁₈O₈

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 374.35

Ref: 5G-89173

Casticin

CAS: 479-91-4

Formula: C₁₉H₁₈O₈

Color and Shape: Solid

Molecular weight: 374.3

Ref: BE-RMT11396

Vitexicarpin

CAS: 479-91-4

Formula: C₁₉H₁₈O₈

Color and Shape: Solid

Molecular weight: 374.3

Ref: BE-RMT13390

CASTICIN

CAS: 479-91-4

Purity: 98%

Molecular weight: 374.3450012

Ref: 10-F795502

Vitexicarpin

CAS: 479-91-4

Vitexicarpin is a type of flavonoid compound, which is derived from plants in the Vitex genus, commonly known as the chaste tree. This naturally occurring bioactive compound acts primarily through the inhibition of various signaling pathways involved in inflammation and cancer progression. Its mechanism often targets pathways such as NF-kB and MAPK, which play crucial roles in inflammatory responses and cellular proliferation.

Formula: C₁₉H₁₈O₈

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 374.34 g/mol

Ref: 3D-FV73793