CAS 480-11-5
:Oroxylin A
Description:
Oroxylin A, with the CAS number 480-11-5, is a flavonoid compound primarily found in various plants, particularly in the roots of the medicinal herb Scutellaria baicalensis. It is characterized by its yellowish color and is known for its diverse biological activities, including antioxidant, anti-inflammatory, and neuroprotective properties. Structurally, Oroxylin A features a flavone backbone, which contributes to its ability to interact with various biological targets. This compound has garnered interest in pharmacological research due to its potential therapeutic effects, including its role in modulating signaling pathways related to cell survival and apoptosis. Additionally, Oroxylin A has been studied for its effects on cognitive function and its potential use in treating neurodegenerative diseases. Its solubility in organic solvents and limited solubility in water are important characteristics that influence its bioavailability and application in medicinal formulations. Overall, Oroxylin A represents a significant compound in the field of natural products and pharmacognosy, with ongoing research aimed at elucidating its full therapeutic potential.
Formula:C16H12O5
InChI:InChI=1S/C16H12O5/c1-20-16-11(18)8-13-14(15(16)19)10(17)7-12(21-13)9-5-3-2-4-6-9/h2-8,18-19H,1H3
InChI key:InChIKey=LKOJGSWUMISDOF-UHFFFAOYSA-N
SMILES:OC1=C2C(OC(=CC2=O)C3=CC=CC=C3)=CC(O)=C1OC
Synonyms:- 4H-1-Benzopyran-4-one, 5,7-dihydroxy-6-methoxy-2-phenyl-
- 5,7-Dihydroxy-6-methoxy-2-phenyl-4H-1-benzopyran-4-one
- 5,7-dihydroxy-6-methoxy-2-phenyl-4H-chromen-4-one
- 6-Methoxybaicalein
- Baicalein 6-methyl ether
- Flavone, 5,7-dihydroxy-6-methoxy-
- Oroxylin
- oroxylin A
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Found 10 products.
5,7-Dihydroxy-6-Methoxy-2-Phenyl-4H-Chromen-4-One
CAS:5,7-Dihydroxy-6-Methoxy-2-Phenyl-4H-Chromen-4-OnePurity:98%Molecular weight:284.26g/molOroxylin A
CAS:Formula:C16H12O5Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:284.27Oroxylin A
CAS:Oroxylin A has anticancer,.anti-inflammation, antithrombotic,antibacterial, anti-pruritic effects, it can inhibit LPS-induced iNOS and COX-2 gene expression by blocking NF-κB activation. Oroxylin A reverses MDR by G2/M arrest and the underlying mechanism attributed to the suppression of P-gp expression via Chk2/P53/NF-κB signaling pathway. Oroxylin A facilitates memory consolidation through brain-derived neurotrophic factor (BDNF)-TrkB signaling.Formula:C16H12O5Purity:95%~99%Molecular weight:284.267Oroxylin A
CAS:Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.Formula:C16H12O5Purity:98.72% - 99.55%Color and Shape:SolidMolecular weight:284.26Oroxylin A
CAS:Formula:C16H12O5Purity:≥ 95.0%Color and Shape:Pale yellow to yellow powderMolecular weight:284.26Oroxylin a
CAS:Oxygen-heterocyclic compoundFormula:C16H12O5Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:284.27Oroxylin A
CAS:<p>Oroxylin A is a natural flavonoid compound, which is derived from the root of Scutellaria baicalensis, commonly known as Baikal skullcap. It is primarily recognized for its bioactive properties, attributed to its modulation of various biochemical pathways. Oroxylin A acts by inhibiting the activity of certain enzymes, such as cyclooxygenase, and influencing signaling pathways like NF-kB, which are integral to inflammatory responses. It also exhibits potent neuroprotective effects by interacting with GABA_A receptors, thereby influencing neurotransmission.</p>Formula:C16H12O5Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:284.26 g/mol
