CAS 480-36-4
:Linarin
Description:
Linarin, with the CAS number 480-36-4, is a flavonoid glycoside primarily found in various plants, particularly in the genus Lonicera, such as honeysuckle. It is characterized by its chemical structure, which consists of a flavone backbone linked to a sugar moiety, typically rhamnose or glucose. Linarin exhibits several biological activities, including antioxidant, anti-inflammatory, and potential neuroprotective effects, making it of interest in pharmacological research. Its solubility properties are influenced by the glycosidic bond, which can affect its bioavailability and interaction with biological systems. Additionally, linarin has been studied for its potential therapeutic applications, including its role in traditional medicine. The compound is generally recognized for its safety profile, although further studies are necessary to fully understand its mechanisms of action and efficacy in various health contexts. Overall, linarin represents a significant compound in the field of natural products and phytochemistry, contributing to the understanding of plant-derived substances and their health benefits.
Formula:C28H32O14
InChI:InChI=1S/C28H32O14/c1-11-21(31)23(33)25(35)27(39-11)38-10-19-22(32)24(34)26(36)28(42-19)40-14-7-15(29)20-16(30)9-17(41-18(20)8-14)12-3-5-13(37-2)6-4-12/h3-9,11,19,21-29,31-36H,10H2,1-2H3/t11-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1
InChI key:InChIKey=YFVGIJBUXMQFOF-PJOVQGMDSA-N
SMILES:O=C1C=2C(OC(=C1)C3=CC=C(OC)C=C3)=CC(O[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@@H](O)[C@H](O)[C@H]4O)=CC2O
Synonyms:- 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)-β-<smallcap>D</span>-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-
- 5-Hydroxy-4′-methoxyflavone-7-O-rutinoside
- 5-hydroxy-2-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
- 7-[[6-O-(6-Deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)-β-<smallcap>D</span>-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
- Acacetin 7-O-rutinoside
- Acacetin 7-O-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→6)-β-<smallcap>D</span>-glucopyranoside
- Acacetin-7-O-(6′′-O-rhamnose)-β-<span class="text-smallcaps">D</span>-glucoside
- Acacetin-7-O-β-<span class="text-smallcaps">D</span>-rutinoside
- Acaciin
- Buddleoflavonoloside
- Buddleoside
- Linarigenin glycoside
- Linarin
- Linarine
- 7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
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Found 19 products.
Linarin
CAS:Linarin analytical standard provided with w/w absolute assay, to be used for quantitative titration.Formula:C28H32O14Purity:(HPLC) ≥98%Color and Shape:PowderMolecular weight:592.56Linarin
CAS:Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivativesFormula:C28H32O14Color and Shape:White PowderMolecular weight:592.17921Linarin
CAS:Formula:C28H32O14Purity:(HPLC) ≥ 95.0%Color and Shape:White to off-white or pale yellow powderMolecular weight:592.55Diosmin EP Impurity E (Linarin)
CAS:Formula:C28H32O14Color and Shape:Pale Yellow To Off-White SolidMolecular weight:592.55Linarin (Standard)
CAS:Linarin (Standard) is a reference standard for research and analysis in studies involving Linarin. 1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediated apoptotic pathways. 3. Linarin prevents A beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2. 4. The piperine significantly enhanced the oral absorption of Linarin in rats by inhibiting P-glycoprotein mediated cellular efflux during the intestinal absorption and likely simultaneously by inhibiting the metabolism of Linarin.Formula:C28H32O14Color and Shape:SolidMolecular weight:592.55Acaciin
CAS:Linarin is a flavone glycoside in the plants Flos chrysanthemi indici, Buddleja officinalis, Cirsium setosum, Mentha arvensis and Buddleja davidii, possesses analgesic, antipyretic, anti-inflammatory and neuroprotective activities.Formula:C28H32O14Purity:95%~99%Color and Shape:Yellow powderMolecular weight:592.55Linarin
CAS:Formula:C28H32O14Purity:>95.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:592.55Linarin
CAS:Linarin inhibits acetylcholinesterase, reduces liver injury via TNF-α, protects neurons via PI3K/Akt, and has enhanced absorption with piperine.Formula:C28H32O14Purity:97.95% - 98.27%Color and Shape:White SolidMolecular weight:592.55Buddleoside
CAS:5-Hydroxy-2-(4-methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-oneFormula:C28H32O14Purity:98%Molecular weight:592.55Linarin
CAS:Natural glycosideFormula:C28H32O14Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:592.55Linarine
CAS:Controlled ProductImpurity Diosmin EP Impurity E
Stability Hygroscopic
Applications Linarine (Diosmin EP Impurity E) is a naturally occurring flavone glycoside that was identified to possess potential sedative and anticonvulsant properties.
References Nugroho, A., et al.: Arch. Pharma. Res., 36, 51 (2013); Jung, H.A., et al.: Arch. Pharma. Res., 35, 1021 (2012); Shen, H.J., et al.: J. Med. Plants. Res., 5, 6555 (2011);Formula:C28H32O14Color and Shape:NeatMolecular weight:592.545Linarin
CAS:Linarin is a naturally occurring flavonoid compound, which is primarily extracted from plant sources such as the leaves of *Buddleja davidii* and *Mentha aquatica*. This flavonoid is notable for its biological activity, which is characterized by its interaction with various enzymes and receptors involved in cellular processes.Formula:C28H33O14Purity:Min. 95%Color and Shape:PowderMolecular weight:593.55 g/mol
