CAS 4800-94-6: Carbenicillin disodium

Description: Carbenicillin disodium is a semisynthetic penicillin antibiotic that is primarily used to treat infections caused by certain Gram-negative bacteria. It is characterized by its ability to inhibit bacterial cell wall synthesis, which is a crucial mechanism for its antibacterial activity. The disodium salt form enhances its solubility in water, making it suitable for intravenous administration. Carbenicillin is particularly effective against Pseudomonas aeruginosa and some strains of Escherichia coli, among other pathogens. Its chemical structure includes a beta-lactam ring, which is essential for its antibacterial properties, and a carboxyl group that contributes to its spectrum of activity. However, like other beta-lactam antibiotics, carbenicillin is susceptible to hydrolysis by beta-lactamases produced by resistant bacteria. Common side effects may include allergic reactions, gastrointestinal disturbances, and potential disruption of normal flora. Due to the emergence of resistant strains, its use has become more limited, and it is often reserved for specific clinical situations where other antibiotics may not be effective.

Formula: C₁₇H₁₈N₂O₆S·2Na

InChI: InChI=1S/C17H18N2O6S.2Na/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25);;/t9?,10-,11+,14-;;/m1../s1

InChI key: InChIKey=MYWJHWLQHFVZCY-YCAHSCEMSA-N

SMILES: [Na].O=C(O)C(C(=O)NC1C(=O)N2C1SC(C)(C)C2C(=O)O)C=3C=CC=CC3

Synonyms:

• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(2-carboxy-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-, sodium salt (1:2), (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt, (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt, [2S-(2α,5α,6β)]-
• Anabactyl
• Brl 2064
• Carbapen
• Carbecin
• Carbenicillin Disodium
• Carbenicillin Sodium
• Carbenicilline disodium
• Carboxybenzylpenicillin sodium
• Cp 15639-2
• Disodium (α-carboxybenzyl)penicillin
• Disodium 6-{[Carboxylato(Phenyl)Acetyl]Amino}-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate
• Disodium [2S-(2Alpha,5Alpha,6Beta)]-6-(Carboxylatophenylacetamido)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate
• Disodium carbenicillin
• Fugacillin
• Geocillin
• Geopen
• Gripenin
• Hyoper
• Malonamic acid, N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-2-phenyl-, disodium salt
• Microcillin
• NSC 111071
• Piopen
• Pyopen
• Pyopene
• Sodium carbenicillin
• disodium (2S,5R,6R)-6-{[carboxylato(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• α-Carboxybenzylpenicillin disodium salt
• α-Carboxybenzylpenicillin sodium salt

Carbenicillin disodium salt

CAS: 4800-94-6

Carbenicillin disodium salt is a water-soluble antibiotic which is effective against gram-negative bacteria.Carbenicillin disodium salt …

• Formula: C₁₇H₁₆N₂Na₂O₆S
• Color and Shape: White to cream, Crystalline powder
• Molecular weight: 422.36

Carbenicillin disodium salt, 50 mg/ml in distilled water, sterile-filtered

CAS: 4800-94-6

Used for selection of ampr transformed cells and to study the role of penicillin-sensitive transpeptidases …

• Formula: C₁₇H₁₆N₂Na₂O₆S
• Color and Shape: Liquid, Clear colorless to light yellow
• Molecular weight: 422.36

Carbenicillin sodium CRS

CAS: 4800-94-6

• Formula: C₁₇H₁₆N₂Na₂O₆S
• Molecular weight: 422.3633

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt,(2S,5R,6R)-

CAS: 4800-94-6

• Formula: C₁₇H₁₆N₂Na₂O₆S
• Purity: 90%
• Color and Shape: Solid
• Molecular weight: 422.36328

Carbenicillin disodium

CAS: 4800-94-6

• Formula: C₁₇H₁₆N₂O₆S·2Na
• Purity: By hplc: 99.7% by area (Typical Value in Batch COA)
• Color and Shape: white to off white powder
• Molecular weight: 422.36g/mol

Carbenicillin disodium salt

CAS: 4800-94-6

• Formula: C₁₇H₁₆N₂Na₂O₆S
• Purity: 89.0 - 109.0 % (dried basis)
• Color and Shape: White to pale yellow crystalline powder
• Molecular weight: 422.36

Carbenicillin disodium

CAS: 4800-94-6

• Purity: 750mcg/mg
• Molecular weight: 422.36g/mol

Carbenicillin Disodium (Mixture of Diastereomers)

CAS: 4800-94-6

• Formula: C₁₇H₁₆N₂O₆S·2Na
• Molecular weight: 376.39 2*22.99

Carbenicillin disodium salt, USP grade

CAS: 4800-94-6

• Formula: C₁₇H₁₆N₂Na₂O₆S
• Purity: (HPLC) 89.0 - 100.5 %
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 422.36

Carbenicillin.Disodium

CAS: 4800-94-6

M01626 - Carbenicillin.Disodium

• Formula: C₁₇H₁₆N₂Na₂O₆S
• Purity: 90%
• Color and Shape: Solid
• Molecular weight: 422.3599853515625

Carbenicillin disodium salt, 90%

CAS: 4800-94-6

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₇H₁₆N₂Na₂O₆S
• Purity: 90%
• Color and Shape: White to light yellow, Powder or crystalline powder
• Molecular weight: 422.36

Carbenicillin disodium

CAS: 4800-94-6

Carbenicillin disodium (BRL-2064) is a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity.

• Formula: C₁₇H₁₆N₂Na₂O₆S
• Purity: 750mcg/mg - 96.62%
• Color and Shape: Almost White Solid
• Molecular weight: 422.36

Carbenicillin (100mg/ml)

CAS: 4800-94-6

• Color and Shape: Solution
• Molecular weight: 422.36g/mol

Carbenicillin Disodium (90%)

CAS: 4800-94-6

Applications Semi-synthetic antibiotic related to Penicillin (P223500). Antibacterial. References Naumann, K., et al.: Arzneim. Forsch., …

• Formula: C₁₇H₁₆N₂O₆SNa
• Purity: 90%
• Color and Shape: Neat
• Molecular weight: 422.36

Carbenicillin disodium salt

CAS: 4800-94-6

Inhibitor of bacterial cell wall biogenesis; penicillin class

• Formula: C₁₇H₁₆N₂Na₂O₆S
• Purity: Min. 90 Area-%
• Color and Shape: White Slightly Yellow Powder
• Molecular weight: 422.37 g/mol

Carbenicillin monosodium salt

CAS: 4800-94-6

Inhibitor of bacterial cell wall biogenesis; penicillin class

• Formula: C₁₇H₁₇N₂NaO₆S
• Purity: Min. 90 Area-%
• Color and Shape: Powder
• Molecular weight: 400.38 g/mol

Carbenicillin Disodium (mixture of isomers)

CAS: 4800-94-6

• Formula: C₁₇H₁₆N₂Na₂O₆S
• Purity: >95.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 422.36

Carbenicillin Disodium Salt for tissue culture, 90%

CAS: 4800-94-6

• Formula: C₁₇H₁₆N₂Na₂O₆S
• Purity: min. 90%
• Color and Shape: White to off white, Powder
• Molecular weight: 422.4

Carbenicillin Disodium Salt, 90%

CAS: 4800-94-6

• Formula: C₁₇H₁₆N₂Na₂O₆S
• Purity: min. 90%
• Color and Shape: White to off-white, Powder
• Molecular weight: 422.4

Carbenicillin Sodium Monohydrate (~80%)

CAS: 4697-36-3 4800-94-6

• Formula: C₁₇H₁₈N₂O₆S·x(Na)·H₂O
• Purity: ~80%
• Color and Shape: Neat
• Molecular weight: 378.40 + x(22.99) + 18.02