CAS 481-39-0
:Juglone
Description:
Juglone, with the CAS number 481-39-0, is a naturally occurring naphthoquinone compound primarily found in the black walnut tree (Juglans nigra) and other members of the Juglandaceae family. It is characterized by its yellow to brown color and has a molecular formula of C10H6O3. Juglone exhibits a range of biological activities, including antimicrobial, antifungal, and herbicidal properties, making it of interest in both ecological and agricultural contexts. The compound is known to inhibit the growth of certain plants and microorganisms, which contributes to the allelopathic effects observed in black walnut trees. In addition to its ecological significance, juglone has been studied for potential therapeutic applications, including its effects on cancer cells. However, it is also important to note that juglone can be toxic to certain organisms, including livestock and pets, if ingested in significant amounts. Its solubility in organic solvents and limited solubility in water further influence its behavior in environmental and biological systems.
Formula:C10H6O3
InChI:InChI=1/C10H6O3/c11-7-4-5-9(13)10-6(7)2-1-3-8(10)12/h1-5,12H
InChI key:InChIKey=KQPYUDDGWXQXHS-UHFFFAOYSA-N
SMILES:O=C1C=2C(C(=O)C=C1)=C(O)C=CC2
Synonyms:- 1,4-Dihydro-1,4-dioxo-5-hydroxynaphthalene
- 1,4-Naphthalenedione, 5-hydroxy-
- 1,4-Naphthoquinone, 5-hydroxy-
- 5-Hidroxi-1,4-Naftoquinona
- 5-Hydrocy-1,4-Naphthoquinone
- 5-Hydroxy-1,4-naphthalenedione
- 5-Hydroxy-1,4-naphthochinon
- 5-Hydroxy-1,4-naphthoquinone
- 5-Hydroxy-1,4-naphtoquinone
- 5-Hydroxynaphthalene-1,4-Dione
- 5-Hydroxynaphthoquinone
- 8-Hydroxy-1,4-naphthoquinone
- Akhnot
- Juglon
- Juglone
- Natural Brown 7
- Nsc 153189
- Nsc 34266
- Nsc 622948
- Nucin
- Regianin
- Walnut Extract
- C.I. Natural Brown 7
- C.I. 75500
- 8-hydroxy-4-naphthoquinone
- 5-HYDROXY-P-NAPHTHOQUINONE
- 5-hydroxy-4-naphthalenedione
- WALNUT EXTRACT, WATER SOLUBLE
- 1,4-Naphthoquinone, 8-hydroxy-
- 5-hydroxy-4-naphthoquinone
- RARECHEM BW GC 0025
- 5-Hydroxy-1,4-naftochinon
- 5-HYDROXY-1,4-NAPHTHLENEDIONE
- 8-Hydroxy-1,4-naphthalenedione
- See more synonyms
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5-Hydroxy-1,4-naphthoquinone
CAS:Formula:C10H6O3Purity:>96.0%(GC)Color and Shape:Orange to Amber to Dark red powder to crystalMolecular weight:174.16Juglone
CAS:Formula:C10H6O3Purity:≥ 98.0%Color and Shape:Brown to orange powderMolecular weight:174.165-Hydroxy-1,4-naphthalenedione
CAS:Formula:C10H6O3Purity:97%Color and Shape:SolidMolecular weight:174.1528Juglone (Standard)
CAS:Juglone (Standard) is a reference standard for research and analysis in studies involving Juglone. Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 μM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent mechanisms.Formula:C10H6O3Molecular weight:174.15285-Hydroxy-1,4-naphthoquinone
CAS:Controlled ProductApplications 5-Hydroxy-1,4-naphthoquinone is used in the synthesis of novel 5,6-fused hybrid napthoquinones as effective anticancer agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mallavadhani, U. et al.: Eur. J. Med. Chem., 83, 84 (2014); Spoerlein-Guettler, C. et al.: J. Inorg. Biochem., 138, 64 (2014);Formula:C10H6O3Color and Shape:NeatMolecular weight:174.155-Hydroxy-1,4-naphthalenedione
CAS:5-Hydroxy-1,4-naphthalenedioneFormula:C10H6O3Purity:97%Molecular weight:174.15Juglone
CAS:Juglone is a naphthoquinone from walnut and Juglandaceae, inhibits peptidyl-prolyl isomerases, RNA polymerases, and reduces rat kidney fibrosis.Formula:C10H6O3Purity:99.24%Color and Shape:SolidMolecular weight:174.1528Juglone
CAS:QuinoneFormula:C10H6O3Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:174.165-Hydroxy-1,4-naphthalenedione
CAS:Blocks RNA polymerases I, II, and III; inhibits PPlasesFormula:C10H6O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:174.15 g/mol5-Hydroxy-1,4-naphthalenedione
CAS:Formula:C10H6O3Purity:97%Color and Shape:LiquidMolecular weight:174.155
