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CAS 481-49-2

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(+)-Cepharanthine

Description:
(+)-Cepharanthine is a natural alkaloid derived from the plant species Stephania cepharantha, belonging to the family Menispermaceae. It is characterized by its complex tetracyclic structure, which includes a phenanthrene core. This compound exhibits a range of biological activities, including anti-inflammatory, antitumor, and antiviral properties, making it of interest in pharmacological research. (+)-Cepharanthine is known for its ability to modulate immune responses and has been studied for its potential therapeutic applications in various diseases. The substance is typically found as a white to pale yellow crystalline powder and is soluble in organic solvents but has limited solubility in water. Its stereochemistry, indicated by the (+) designation, refers to its specific optical activity, which is a crucial aspect of its interaction with biological systems. As with many natural products, the extraction and purification of (+)-Cepharanthine can be challenging, necessitating advanced techniques to obtain it in sufficient purity for research and potential clinical use.
Formula:C37H38N2O6
InChI:InChI=1S/C37H38N2O6/c1-38-13-11-24-18-31(41-4)33-20-27(24)28(38)16-23-7-10-30(40-3)32(17-23)44-26-8-5-22(6-9-26)15-29-35-25(12-14-39(29)2)19-34-36(37(35)45-33)43-21-42-34/h5-10,17-20,28-29H,11-16,21H2,1-4H3/t28-,29+/m1/s1
InChI key:InChIKey=YVPXVXANRNDGTA-WDYNHAJCSA-N
SMILES:CN1[C@@]2(C=3C(=C4C(=CC3CC1)OCO4)OC=5C=C6[C@@](CC=7C=C(OC=8C=CC(C2)=CC8)C(OC)=CC7)(N(C)CCC6=CC5OC)[H])[H]
Synonyms:
  • (14S,27R)-22,33-dimethoxy-13,28-dimethyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.2~16,19~.1~3,10~.1~21,25~.0~4,8~.0~14,39~.0~31,35~]nonatriaconta-1(33),3,8,10(39),16,18,21(36),22,24,31,34,37-dodecaene (non-preferred name)
  • (14aS,26aR)-2,3,13,14,14a,15,26,26a-Octahydro-22,30-dimethoxy-1,14-dimethyl-1H-4,6:16,19-dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2′,3′:17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline
  • 1H-4,6:16,19-Dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2′,3′:17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline, 2,3,13,14,14a,15,26,26a-octahydro-22,30-dimethoxy-1,14-dimethyl-, (14aS,26aR)-
  • 1H-4,6:16,19-Dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2′,3′:17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline, 2,3,13,14,14a,15,26,26a-octahydro-22,30-dimethoxy-1,14-dimethyl-, [14aS-(14aR*,26aS*)]-
  • 22,33-Dimethoxy-13,28-Dimethyl-2,5,7,20-Tetraoxa-13,28-Diazaoctacyclo[25.6.2.2~16,19~.1~3,10~.1~21,25~.0~4,8~.0~14,39~.0~31,35~]Nonatriaconta-1(33),3,8,10(39),16,18,21(36),22,24,31,34,37-Dodecaene (Non-Preferred Name)
  • Cepharanthin
  • Cepharantin
  • NSC 623442
  • O-Methylcepharanoline
  • Oxyacanthan, 6′,12′-dimethoxy-2,2′-dimethyl-6,7-[methylenebis(oxy)]-
  • See more synonyms
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