CAS 481-49-2

(+)-Cepharanthine

Description:

(+)-Cepharanthine is a natural alkaloid derived from the plant species Stephania cepharantha, belonging to the family Menispermaceae. It is characterized by its complex tetracyclic structure, which includes a phenanthrene core. This compound exhibits a range of biological activities, including anti-inflammatory, antitumor, and antiviral properties, making it of interest in pharmacological research. (+)-Cepharanthine is known for its ability to modulate immune responses and has been studied for its potential therapeutic applications in various diseases. The substance is typically found as a white to pale yellow crystalline powder and is soluble in organic solvents but has limited solubility in water. Its stereochemistry, indicated by the (+) designation, refers to its specific optical activity, which is a crucial aspect of its interaction with biological systems. As with many natural products, the extraction and purification of (+)-Cepharanthine can be challenging, necessitating advanced techniques to obtain it in sufficient purity for research and potential clinical use.

Formula: C₃₇H₃₈N₂O₆

InChI: InChI=1S/C37H38N2O6/c1-38-13-11-24-18-31(41-4)33-20-27(24)28(38)16-23-7-10-30(40-3)32(17-23)44-26-8-5-22(6-9-26)15-29-35-25(12-14-39(29)2)19-34-36(37(35)45-33)43-21-42-34/h5-10,17-20,28-29H,11-16,21H2,1-4H3/t28-,29+/m1/s1

InChI key: InChIKey=YVPXVXANRNDGTA-WDYNHAJCSA-N

SMILES: CN1[C@@]2(C=3C(=C4C(=CC3CC1)OCO4)OC=5C=C6[C@@](CC=7C=C(OC=8C=CC(C2)=CC8)C(OC)=CC7)(N(C)CCC6=CC5OC)[H])[H]

Synonyms:

• (14S,27R)-22,33-dimethoxy-13,28-dimethyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.2~16,19~.1~3,10~.1~21,25~.0~4,8~.0~14,39~.0~31,35~]nonatriaconta-1(33),3,8,10(39),16,18,21(36),22,24,31,34,37-dodecaene (non-preferred name)
• (14aS,26aR)-2,3,13,14,14a,15,26,26a-Octahydro-22,30-dimethoxy-1,14-dimethyl-1H-4,6:16,19-dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2′,3′:17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline
• 1H-4,6:16,19-Dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2′,3′:17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline, 2,3,13,14,14a,15,26,26a-octahydro-22,30-dimethoxy-1,14-dimethyl-, (14aS,26aR)-
• 1H-4,6:16,19-Dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2′,3′:17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline, 2,3,13,14,14a,15,26,26a-octahydro-22,30-dimethoxy-1,14-dimethyl-, [14aS-(14aR*,26aS*)]-
• 22,33-Dimethoxy-13,28-Dimethyl-2,5,7,20-Tetraoxa-13,28-Diazaoctacyclo[25.6.2.2~16,19~.1~3,10~.1~21,25~.0~4,8~.0~14,39~.0~31,35~]Nonatriaconta-1(33),3,8,10(39),16,18,21(36),22,24,31,34,37-Dodecaene (Non-Preferred Name)
• Cepharanthin
• Cepharantin
• NSC 623442
• O-Methylcepharanoline
• Oxyacanthan, 6′,12′-dimethoxy-2,2′-dimethyl-6,7-[methylenebis(oxy)]-
• Sml 1269
• Stephanotis

Cepharanthine

CAS: 481-49-2

Cepharanthine (NSC-623442) is a natural alkaloid. Cepharanthine exhibits anti-inflammatory, antioxidant, and antitumor activities. Cost-effective and quality-assured.

Formula: C₃₇H₃₈N₂O₆

Purity: 99.40% - 99.96%

Color and Shape: Yellow Powder

Molecular weight: 606.71

Ref: TM-T0131

Cepharanthine

CAS: 481-49-2

Cepharanthine

Purity: ≥98%

Molecular weight: 606.71g/mol

Ref: 54-BUP14659

Cepharanthine

CAS: 481-49-2

Cepharanthine

Purity: 98%

Molecular weight: 606.72g/mol

Ref: 54-OR1028063

Cepharanthine

CAS: 481-49-2

Formula: C₃₇H₃₈N₂O₆

Purity: ≥ 95.0%

Color and Shape: White to off-white or beige powder

Molecular weight: 606.71

Ref: 7W-GP8908

Cepharanthine

CAS: 481-49-2

Formula: C₃₇H₃₈N₂O₆

Purity: 95%~99%

Molecular weight: 606.719

Ref: BP-BP0334

Cepharanthine

CAS: 481-49-2

Formula: C₃₇H₃₈N₂O₆

Purity: >90.0%(T)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 606.72

Ref: 3B-M2968

Cepharanthine

CAS: 481-49-2

Natural alkaloid

Formula: C₃₇H₃₈N₂O₆

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 606.72

Ref: 5G-89599

Cepharanthine

CAS: 481-49-2

Competes with eNOS for binding to HSP90α

Formula: C₃₇H₃₈N₂O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 606.71 g/mol

Ref: 3D-FC66045

Cepharanthine

Controlled Product

CAS: 481-49-2

Applications Cepharanthine is a biscoclaurine alkaloid that has antiinflammatory and other biological functions.

Formula: C₃₇H₃₈N₂O₆

Color and Shape: Off-White

Molecular weight: 606.71

Ref: TR-C261513

1H-4,6:16,19-Dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline,2,3,13,14,14a,15,26,26a-octahydro-22,30-dimethoxy-1,14-dimethyl-,(14aS,26aR)-

CAS: 481-49-2

Formula: C₃₇H₃₈N₂O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 606.7074

Ref: IN-DA00I8RC