CAS 483-04-5: Ajmalicine

Description: Ajmalicine, also known as raubasine, is an alkaloid derived from the plant species of the genus Rauvolfia, particularly Rauvolfia serpentina. It is characterized by its complex indole structure, which contributes to its pharmacological properties. Ajmalicine exhibits a range of biological activities, including antihypertensive and sedative effects, making it of interest in medicinal chemistry. The compound acts primarily as a peripheral vasodilator and has been studied for its potential in treating hypertension and other cardiovascular conditions. Ajmalicine's mechanism of action involves the inhibition of certain neurotransmitter receptors, which can lead to a decrease in blood pressure. Additionally, it has been noted for its potential neuroprotective effects. The substance is typically found in the form of a white to off-white crystalline powder and is soluble in organic solvents. Due to its bioactive nature, ajmalicine is also a subject of research in the fields of pharmacology and natural product chemistry, exploring its therapeutic potential and safety profile.

Formula: C₂₁H₂₄N₂O₃

InChI: InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3/t12-,15-,16+,19-/m0/s1

InChI key: InChIKey=GRTOGORTSDXSFK-XJTZBENFSA-N

SMILES: O=C(OC)C1=COC(C)C2CN3CCC=4C=5C=CC=CC5NC4C3CC12

Synonyms:

• 4H-Indolo[2,3-a]pyrano[3,4-g]quinolizine, oxayohimban-16-carboxylic acid deriv.
• 4H-Indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylic acid, 4a,5,7,8,13,13b,14,14a-octahydro-4-methyl-, methyl ester, (4S,4aR,13bS,14aS)-
• Ajmalicin
• Circolene
• Hydrosarpan
• Isoarteril
• Lamuran
• Methyl (19Alpha)-19-Methyl-16,17-Didehydro-18-Oxayohimban-16-Carboxylate
• Methyl 19-Methyl-16,17-Didehydro-18-Oxayohimban-16-Carboxylate
• NSC 72133
• NSC 95087
• Oxayohimban-16-carboxylic acid, 16,17-didehydro-19-methyl-, methyl ester, (19α)-
• Py-tetrahydroserpentine
• Ranitol
• Raubaserp
• Raubasil
• Raubasin
• Raubasine
• Raumalina
• Rauvasan
• Sarpan
• Tensyl
• Tetrahydroserpentine
• Vincain
• Vincaine
• Vincein
• Vinceine
• δ-Yohimbine
• Ajmalicine

Oxayohimban-16-carboxylic acid, 16,17-didehydro-19-methyl-, methylester, (19a)-

CAS: 483-04-5

• Formula: C₂₁H₂₄N₂O₃
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 352.4269

Ajmalicine

CAS: 483-04-5

• Purity: 96%
• Molecular weight: 352.43g/mol

Raubasine

CAS: 483-04-5

• Formula: C₂₁H₂₄N₂O₃
• Color and Shape: Pale Yellow Solid
• Molecular weight: 352.44

Ajmalicine

CAS: 483-04-5

Ajmalicine (Raubasine): Blocks α1-adrenoceptor, non-competitive nicotine receptor inhibitor (IC50=72.3 μM), anti-hypertensive, sedative.

• Formula: C₂₁H₂₄N₂O₃
• Purity: 96.9%
• Color and Shape: Solid
• Molecular weight: 352.43

Raubasine

CAS: 483-04-5

• Formula: C₂₁H₂₄N₂O₃
• Purity: 98%
• Molecular weight: 352.434

Ajmalicine

CAS: 483-04-5

• Formula: C₂₁H₂₄N₂O₃
• Purity: ≥ 98.0%
• Color and Shape: White to off-white solid
• Molecular weight: 352.43

Ajmalicine

CAS: 483-04-5

Natural alkaloid

• Formula: C₂₁H₂₄N₂O₃
• Purity: ≥ 98.0 % (HPLC)
• Color and Shape: Powder
• Molecular weight: 352.43

Raubasine

CAS: 483-04-5

Applications Antihypertensive, anti-ischemic. References Caillet, S., et al.: Food Chem., 124, 1699 (2010), Dresen, S., …

• Formula: C₂₁H₂₄N₂O₃
• Color and Shape: Neat
• Molecular weight: 352.43

Raubasine

CAS: 483-04-5

Please enquire for more information about Raubasine including the price, delivery time and more detailed …

• Formula: C₂₁H₂₄N₂O₃
• Purity: Min. 95%
• Color and Shape: Solid
• Molecular weight: 352.43 g/mol

Ajmalicine (Raubasine) extrapure, 98%

CAS: 483-04-5

• Formula: C₂₁H₂₄N₂O₃
• Color and Shape: Off - white to pale yellow, Powder
• Molecular weight: 352.43