CAS 483-14-7: (-)-Tetrahydropalmatine

Description: (-)-Tetrahydropalmatine (CAS 483-14-7) is an alkaloid derived from the plant species *Stephania* and is known for its structural similarity to other isoquinoline alkaloids. It typically appears as a white to off-white crystalline powder and is characterized by its chiral nature, with the "(-)" designation indicating its specific optical rotation. This compound exhibits a range of pharmacological properties, including sedative, analgesic, and anti-addictive effects, making it of interest in both traditional medicine and modern pharmacology. Its mechanism of action is thought to involve interactions with dopamine receptors, particularly in the central nervous system. Additionally, (-)-Tetrahydropalmatine has been studied for its potential therapeutic applications in treating conditions such as anxiety and substance use disorders. Due to its biological activity, it is important to handle this compound with care, adhering to safety protocols in laboratory settings. Overall, (-)-Tetrahydropalmatine represents a significant compound in the field of natural products and medicinal chemistry.

Formula: C₂₁H₂₅NO₄

InChI: InChI=1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3/t17-/m0/s1

InChI key: InChIKey=AEQDJSLRWYMAQI-KRWDZBQOSA-N

SMILES: O(C1=CC=C2C(=C1OC)CN3CCC4=CC(OC)=C(OC)C=C4C3C2)C

Synonyms:

• (-)-2,3,9,10-Tetramethoxyberbine
• (-)-Corydalis B
• (-)-Rotundine
• (-)-S-Tetrahydropalmatine
• (-)-Tetrahydropalmatine
• (13AS)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline
• (13aS)-5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H-dibenzo[a,g]quinolizine
• 13aa-Berbine, 2,3,9,10-tetramethoxy-(8CI)
• 13aα-Berbine, 2,3,9,10-tetramethoxy-
• 6H-Dibenzo[a,g]quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-,(S)-
• Caseanine
• Cyclanoline, O,O-dimethyl-N-demethyl-
• Cyclanoline, O,O-dimethyl-N-demethyl- (6CI)
• Gindarine
• Gindarine (7CI)
• Hyndarine
• N-Demethyl-O,O'-dimethylcyclanoline
• N-Demethyl-O,O'-dimethylsteponine
• Palmatine, tetrahydro-, (-)-
• Rotundine (Stephania), (-)-
• l-Tetrahydropalmatine
• 6H-Dibenzo[a,g]quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, (13aS)-

L-Tetrahydropalmatine

CAS: 483-14-7

• Formula: C₂₁H₂₅NO₄
• Purity: >98.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 355.43

Tetrahydropalmatine

CAS: 483-14-7

Tetrahydropalmatine analytical standard provided with chromatographic purity, to be used as reference material for qualitative …

• Formula: C₂₁H₂₅NO₄
• Purity: (HPLC) ≥95%
• Color and Shape: Powder
• Molecular weight: 355.44

rotundine

CAS: 483-14-7

• Formula: C₂₁H₂₅NO₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 355.4275

L-Tetrahydropalmatine

CAS: 483-14-7

• Molecular weight: 355.43g/mol

Rotundine

CAS: 483-14-7

• Purity: 99.8%
• Molecular weight: 355.43g/mol

L-Tetrahydropalmatine

CAS: 483-14-7

• Formula: C₂₁H₂₅NO₄
• Purity: 95%~99%
• Molecular weight: 355.434

Rotundine

CAS: 483-14-7

• Formula: C₂₁H₂₅NO₄
• Color and Shape: Neat
• Molecular weight: 355.43

Rotundine

CAS: 483-14-7

• Formula: C₂₁H₂₅NO₄
• Molecular weight: 355.44

Tetrahydropalmatine

CAS: 483-14-7

• Formula: C₂₁H₂₅NO₄
• Purity: ≥ 98.0%
• Color and Shape: White to off-white or pale yellow powder or crystals
• Molecular weight: 355.43

Rotundine

CAS: 483-14-7

Rotundine (Gindarine) (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 …

• Formula: C₂₁H₂₅NO₄
• Purity: 100% - 99.8%
• Color and Shape: Off-White Solid
• Molecular weight: 355.43

L-Tetrahydropalmatine

CAS: 483-14-7

• Purity: 95.0%
• Color and Shape: Solid
• Molecular weight: 355.4339904785156

Rotundine

CAS: 483-14-7

• Formula: C₂₁H₂₅NO₄
• Color and Shape: Off-White
• Molecular weight: 355.43

Rotundine

CAS: 483-14-7

Alkaloid found in Corydalis yanhusuo root, which is an herbal pain remedy

• Formula: C₂₁H₂₅NO₄
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 355.43 g/mol