CAS 483-14-7

(-)-Tetrahydropalmatine

Description:

(-)-Tetrahydropalmatine (CAS 483-14-7) is an alkaloid derived from the plant species *Stephania* and is known for its structural similarity to other isoquinoline alkaloids. It typically appears as a white to off-white crystalline powder and is characterized by its chiral nature, with the "(-)" designation indicating its specific optical rotation. This compound exhibits a range of pharmacological properties, including sedative, analgesic, and anti-addictive effects, making it of interest in both traditional medicine and modern pharmacology. Its mechanism of action is thought to involve interactions with dopamine receptors, particularly in the central nervous system. Additionally, (-)-Tetrahydropalmatine has been studied for its potential therapeutic applications in treating conditions such as anxiety and substance use disorders. Due to its biological activity, it is important to handle this compound with care, adhering to safety protocols in laboratory settings. Overall, (-)-Tetrahydropalmatine represents a significant compound in the field of natural products and medicinal chemistry.

Formula: C₂₁H₂₅NO₄

InChI: InChI=1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3/t17-/m0/s1

InChI key: InChIKey=AEQDJSLRWYMAQI-KRWDZBQOSA-N

SMILES: O(C)C=1C=C2[C@]3(N(CC=4C(C3)=CC=C(OC)C4OC)CCC2=CC1OC)[H]

Synonyms:

• (-)-2,3,9,10-Tetramethoxyberbine
• (-)-Corydalis B
• (-)-Rotundine
• (-)-S-Tetrahydropalmatine
• (-)-Tetrahydropalmatine
• (13AS)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline
• (13aS)-5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H-dibenzo[a,g]quinolizine
• 13aa-Berbine, 2,3,9,10-tetramethoxy-(8CI)
• 13aα-Berbine, 2,3,9,10-tetramethoxy-
• 6H-Dibenzo[a,g]quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-,(S)-
• Caseanine
• Cyclanoline, O,O-dimethyl-N-demethyl-
• Cyclanoline, O,O-dimethyl-N-demethyl- (6CI)
• Gindarine
• Gindarine (7CI)
• Hyndarine
• N-Demethyl-O,O'-dimethylcyclanoline
• N-Demethyl-O,O'-dimethylsteponine
• Palmatine, tetrahydro-, (-)-
• Rotundine (Stephania), (-)-
• l-Tetrahydropalmatine
• 6H-Dibenzo[a,g]quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, (13aS)-
• (S)-Tetrahydrop
• (13aS)-2,3,9,10-Tetramethoxy-5,6,13,13a-tetrahydro-8H-dibenzo[a,g]quinolizine
• O,O-DiMethyl-N-deMethyl-cyclanoline
• TETRAHYDROPALMATINE, L-(P)
• (S)-Tetrahydropalmitine
• (S)-2,3,9,10-Tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[3,2-a]isoquinoline
• (13aS)-2,3,9,10-Tetramethoxy-5,8,13,13a-tetrahydro-6H-dibenzo[a,g]quinolizine
• ROTUNDINE 98+%
• Rotundine?, BR

L-Tetrahydropalmatine

CAS: 483-14-7

Formula: C₂₁H₂₅NO₄

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 355.43

Ref: 3B-T3311

Tetrahydropalmatine

CAS: 483-14-7

Tetrahydropalmatine analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₂₁H₂₅NO₄

Purity: (HPLC) ≥95%

Color and Shape: Powder

Molecular weight: 355.44

Ref: 11-0691

Rotundine

CAS: 483-14-7

Formula: C₂₁H₂₅NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 355.4275

Ref: IN-DA00DEBK

L-Tetrahydropalmatine

CAS: 483-14-7

L-Tetrahydropalmatine

Purity: 98%

Molecular weight: 355.43g/mol

Ref: 54-OR1030215

Rotundine

CAS: 483-14-7

Rotundine

Purity: ≥98%

Molecular weight: 355.43g/mol

Ref: 54-BUP16054

L-Tetrahydropalmatine

CAS: 483-14-7

Formula: C₂₁H₂₅NO₄

Purity: 95%~99%

Molecular weight: 355.434

Ref: BP-BP0888

Rotundine

CAS: 483-14-7

Rotundine (Gindarine) (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.

Formula: C₂₁H₂₅NO₄

Purity: 99.8% - 99.91%

Color and Shape: Off-White Solid

Molecular weight: 355.43

Ref: TM-T6648

Rotundine

CAS: 483-14-7

Formula: C₂₁H₂₅NO₄

Molecular weight: 355.44

Ref: 4Z-R-091001

Tetrahydropalmatine

CAS: 483-14-7

Formula: C₂₁H₂₅NO₄

Purity: ≥ 98.0%

Color and Shape: White to off-white or pale yellow powder or crystals

Molecular weight: 355.43

Ref: 7W-GP8987

Rotundine

Controlled Product

CAS: 483-14-7

Formula: C₂₁H₂₅NO₄

Color and Shape: Off-White

Molecular weight: 355.43

Ref: TR-R700760

Rotundine

CAS: 483-14-7

Alkaloid found in Corydalis yanhusuo root, which is an herbal pain remedy

Formula: C₂₁H₂₅NO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 355.43 g/mol

Ref: 3D-FR27764

L-Tetrahydropalmatine

CAS: 483-14-7

Formula: C₂₁H₂₅NO₄

Purity: 98%+(HPLC);RG

Color and Shape: Solid

Molecular weight: 355.434

Ref: 10-F215248

Rotundine

Controlled Product

CAS: 483-14-7

Formula: C₂₁H₂₅NO₄

Color and Shape: Neat

Molecular weight: 355.43

Ref: 04-C16820100