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CAS 483-63-6

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Crotamiton

Description:
Crotamiton is an organic compound primarily used as a topical medication for the treatment of scabies and other skin conditions. It is classified as a sulfonamide and has both antipruritic (itch-relieving) and scabicidal properties. The chemical structure of crotamiton includes a 4-ethyl-2-methylphenol moiety, which contributes to its pharmacological effects. It is typically formulated as a cream or lotion for direct application to the affected areas of the skin. Crotamiton is known for its relatively low toxicity and is generally well-tolerated, although some individuals may experience skin irritation or allergic reactions. The mechanism of action involves disrupting the nervous system of the scabies mite, leading to its elimination. Additionally, crotamiton is often used in conjunction with other treatments to enhance efficacy. It is important to follow medical guidance when using crotamiton to ensure proper application and to minimize potential side effects. As with any medication, contraindications and interactions with other drugs should be considered.
Formula:C13H17NO
InChI:InChI=1S/C13H17NO/c1-4-8-13(15)14(5-2)12-10-7-6-9-11(12)3/h4,6-10H,5H2,1-3H3
InChI key:InChIKey=DNTGGZPQPQTDQF-UHFFFAOYSA-N
SMILES:N(C(C=CC)=O)(CC)C1=C(C)C=CC=C1
Synonyms:
  • (2E)-N-ethyl-N-(2-methylphenyl)but-2-enamide
  • 2-(acetyloxy)-N,N,N-trimethylethanaminium chloride
  • 2-Butenamide, N-ethyl-N-(2-methylphenyl)-
  • Crotalgin
  • Crotamitex
  • Crotamitone
  • Crotonyl N-ethyl-o-toluidine
  • Eurax
  • Euraxil
  • N-Crotonyl-N-ethyl-o-toluidine
  • See more synonyms
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