CAS 4836-13-9

N4-Benzoyl-2′-deoxycytidine

Description:

N4-Benzoyl-2′-deoxycytidine, with the CAS number 4836-13-9, is a modified nucleoside that features a benzoyl group attached to the nitrogen atom at the 4-position of the cytidine base. This compound is characterized by its structural components, which include a deoxyribose sugar and a pyrimidine base, specifically cytidine. The benzoyl modification enhances its lipophilicity and can influence its biological activity, making it of interest in medicinal chemistry and molecular biology. N4-Benzoyl-2′-deoxycytidine is often studied for its potential applications in antiviral and anticancer therapies, as modifications to nucleosides can affect their interaction with nucleic acids and enzymes. Additionally, this compound may exhibit unique solubility and stability properties compared to unmodified nucleosides, which can be advantageous in drug formulation and delivery. Its synthesis typically involves the acylation of 2′-deoxycytidine, and it can be analyzed using various spectroscopic techniques to confirm its structure and purity.

Formula: C₁₆H₁₇N₃O₅

InChI: InChI=1/C16H17N3O5/c20-9-12-11(21)8-14(24-12)19-7-6-13(18-16(19)23)17-15(22)10-4-2-1-3-5-10/h1-7,11-12,14,20-21H,8-9H2,(H,17,18,22,23)/t11-,12+,14+/m1/s1

InChI key: InChIKey=MPSJHJFNKMUKCN-OUCADQQQSA-N

SMILES: O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=CC(NC(=O)C3=CC=CC=C3)=N1

Synonyms:

• 4-(benzoylamino)-1-(2-deoxy-beta-L-erythro-pentofuranosyl)pyrimidin-2(1H)-one
• 4-N-Benzoyldeoxycytidine
• Benzamide, N-[1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,2-dihydro-2-oxo-4-pyrimidinyl]-
• Cytidine, N-benzoyl-2′-deoxy-
• N-Benzoyl-2′-deoxycytidine
• N-Benzoyldeoxycytidine
• N4-Benzoyl-2'-deoxycytidine
• N⁴-Benzoyl-2′-deoxycytidine
• N⁴-Benzoyldeoxycytidine
• Benzamide, N-[1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,2-dihydro-2-oxo-4-pyrimidinyl]-
• N4-Benzoyldeoxycytidine
• N-Benzoyl-2-Deoxy-Cytidine
• Bz-dC
• DC-N-BZ
• n-benzoyl-2’-deoxy-cytidin
• N(sup 4)benzoyl-2'-deoxycytidine
• NBZ-2'-DC
• N-BZ-DC
• N-[1-(2-Deoxy-β-D-ribofuranosyl)-2-oxo-1,2-dihydropyrimidine-4-yl]benzamide
• N4-BZ-2'-DEOXYCYTIDINE
• DC-BZ 99.0%
• 4-(Benzoylamino)-1-(2-deoxy-beta-L-erythro-pentofuranosyl)-2(1H)-pyrimidinone
• DC-BZ/N-BENZOYL-2''-DEOXY-CYTIDIN
• DC-BZ

N4-Benzoyl-2'-deoxycytidine

CAS: 4836-13-9

Formula: C₁₆H₁₇N₃O₅

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 331.33

Ref: 3B-B3102

N-Benzoyl-2'-deoxycytidine, 98+%

CAS: 4836-13-9

N-Benzoyl-2'-deoxycytidine, 98+%

Formula: C₁₆H₁₇N₃O₅

Purity: 98+%

Molecular weight: 331.33

Ref: 02-H52298

N4-Benzoyl-2'-deoxycytidine

CAS: 4836-13-9

Formula: C₁₆H₁₇N₃O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 331.3233

Ref: IN-DA006WUB

N-Benzoyl-2-Deoxy-Cytidine

CAS: 4836-13-9

N-Benzoyl-2-Deoxy-Cytidine

Purity: 98%

Molecular weight: 331.32g/mol

Ref: 54-OR1014255

N4-Benzoyl-2′-deoxycytidine

CAS: 4836-13-9

N4-Benzoyl-2′-deoxycytidine

Purity: ≥98%

Molecular weight: 331.32g/mol

Ref: 54-BUP16481

N4-Benzoyl-2''-deoxycytidine

CAS: 4836-13-9

Formula: C₁₆H₁₇N₃O₅

Molecular weight: 331.33

Ref: 7W-GN9700

N4-Benzoyl-2'-deoxycytidine

CAS: 4836-13-9

Purity: 98.0%

Color and Shape: Solid, No data available.

Molecular weight: 331.3280029296875

Ref: 10-F434668

N4-Benzoyl-2′-deoxycytidine

CAS: 4836-13-9

N4-Benzoyl-2′-deoxycytidine is a synthetic nucleoside analog of the natural nucleoside deoxycytidine (dC), a competitive inhibitor of DNA polymerase.

Formula: C₁₆H₁₇N₃O₅

Purity: 99.41%

Color and Shape: Solid

Molecular weight: 331.32

Ref: TM-T7961

N4-Benzoyl-2'-deoxycytidine

CAS: 4836-13-9

N4-Benzoyl-2'-deoxycytidine is a fluorescent nucleoside that has been used to study the molecular interactions between sugar residues and the phosphate groups of nucleic acids. It is used as a reagent for glycosidation, which involves the formation of a glycosidic linkage between an alcohol group in a saccharide or oligosaccharide and the hydroxyl group in an aromatic acid. N4-Benzoyl-2'-deoxycytidine has also been synthesized by solid-phase techniques. This synthetic method is based on phosphoramidite chemistry and uses an automated DNA synthesizer to produce oligonucleotides with specific sequences. The synthesis of this nucleoside relies on the use of fluorescent dyes such as fluorescein, rhodamine, and coumarin to monitor progress during synthesis.

Formula: C₁₆H₁₇N₃O₅

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 331.33 g/mol

Ref: 3D-NB02991

N4-Benzoyl-2'-deoxy-a-cytidine

CAS: 4836-13-9

N4-Benzoyl-2'-deoxy-a-cytidine is a novel, modified nucleoside that has shown anticancer and antiviral activity. It is synthesized by the enzymatic oxidation of 2'-deoxyadenosine with benzoyl chloride and sodium bicarbonate. N4-Benzoyl-2'-deoxy-a-cytidine has been shown to activate transcription, increase DNA synthesis, and inhibit virus replication. It also inhibits bacterial growth, but does not appear to have any effect on mammalian cells.

Formula: C₁₆H₁₇N₃O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 331.32 g/mol

Ref: 3D-NB08374

N-Benzoyldeoxycytidine

Controlled Product

CAS: 4836-13-9

Applications N-Benzoyldeoxycytidine is proetected Deoxycytidine (2’-deoxy, D232615) which is a Eg5 kinesin modulator with antiproliferative and apoptosis-inducing activity.
References Hecht, S., et al.: Chem. Res. Toxicol., 17, 588 (2004), Choi, J., et al.: J. Biol. Chem., 281, 38244 (2006), Lao, Y., et al.: Chem. Res. Toxicol., 20, 246 (2007)

Formula: C₁₆H₁₇N₃O₅

Color and Shape: Neat

Molecular weight: 331.32

Ref: TR-B208000