CAS 484-12-8

Osthol

Description:

Osthol, with the CAS number 484-12-8, is a natural coumarin derivative primarily extracted from various plants, including the fruits of the Cnidium monnieri and the seeds of the plant Angelica pubescens. It is characterized by its white crystalline appearance and has a molecular formula of C12H10O3. Osthol exhibits a range of biological activities, including anti-inflammatory, antioxidant, and antimicrobial properties, making it of interest in pharmacological research. Its mechanism of action often involves modulation of various signaling pathways, contributing to its therapeutic potential. Additionally, osthol has been studied for its effects on the central nervous system and its potential role in treating conditions such as anxiety and depression. The compound is soluble in organic solvents but has limited solubility in water, which is a common characteristic of many organic compounds. Due to its bioactive properties, osthol is being explored for applications in traditional medicine and as a potential lead compound in drug development.

Formula: C₁₅H₁₆O₃

InChI: InChI=1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3

InChI key: InChIKey=MBRLOUHOWLUMFF-UHFFFAOYSA-N

SMILES: C(C=C(C)C)C1=C2C(=CC=C1OC)C=CC(=O)O2

Synonyms:

• 2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-buten-1-yl)-
• 2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-butenyl)-
• 7-Methoxy-8-(3-methyl-2-buten-1-yl)-2H-1-benzopyran-2-one
• 7-Methoxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one
• 7-Methoxy-8-(3-methyl-2-butenyl)coumarin
• 7-Methoxy-8-isopentenylcoumarin
• 7-methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one
• 8-(3-Methyl-2-butenyl)herniarin
• Common Cnidium Fruit Extract
• Coumarin, 7-methoxy-8-(3-methyl-2-butenyl)-
• NSC 31868
• Osthol
• Ostol
• Ostole

Osthole

CAS: 484-12-8

Formula: C₁₅H₁₆O₃

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 244.29

Ref: 3B-O0426

OSTHOLE CRS

CAS: 484-12-8

OSTHOLE CRS

Formula: C₁₅H₁₆O₃

Molecular weight: 244.2857

Ref: 41-Y0001207

Osthole

CAS: 484-12-8

Osthole

Formula: C₁₅H₁₆O₃

Purity: >98%

Color and Shape: Solid

Molecular weight: 244.28574

Ref: 54-OR903469

Osthole

CAS: 484-12-8

Osthole

Formula: C₁₅H₁₆O₃

Purity: 99.5%

Molecular weight: 244.29

Ref: 54-BUP16946

Osthol

CAS: 484-12-8

Formula: C₁₅H₁₆O₃

Purity: ≥ 97.0%

Color and Shape: White to off-white powder

Molecular weight: 244.29

Ref: 7W-GP0976

Ostole

CAS: 484-12-8

Formula: C₁₅H₁₆O₃

Color and Shape: Neat

Molecular weight: 244.29

Ref: 04-CA15752000

Osthol

CAS: 484-12-8

Formula: C₁₅H₁₆O₃

Purity: 95%~99%

Molecular weight: 244.29

Ref: BP-BP1047

Osthole (Standard)

CAS: 484-12-8

Osthole (Standard) is a reference standard for research and analysis in studies involving Osthole. Osthole (Osthol), a potential inhibitor of histamine H1 receptor, has been shown to stimulate osteoblast proliferation and differentiation.

Formula: C₁₅H₁₆O₃

Color and Shape: Solid

Molecular weight: 244.2857

Ref: TM-TMSM-2772

Osthol

CAS: 484-12-8

Osthol analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₅H₁₆O₃

Purity: (HPLC) ≥99%

Color and Shape: Powder

Molecular weight: 244.29

Ref: 11-0541S

7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one

CAS: 484-12-8

Formula: C₁₅H₁₆O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 244.2857

Ref: IN-DA00I8S7

Osthole

Controlled Product

CAS: 484-12-8

Applications Osthole inhibits the PI3K/Akt pathway thus inhibiting insulin-like growth factor-1 (IGF-1)-induced epithelial-to-mesenchymal transition (EMT) in brain cancer. Osthole may be used in the treatment of Glioblastoma multiforme (GBM).
References Lin, Y., et. al.: J. Agr. Food Chem., 62, 5061 (2014)

Formula: C₁₅H₁₆O₃

Color and Shape: Neat

Molecular weight: 244.29

Ref: TR-O703570

Osthole-13C-d3

CAS: 484-12-8

Formula: C₁₄₁₃CH₁₃D₃O₃

Molecular weight: 248.30

Ref: 4Z-C-1646

7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one

CAS: 484-12-8

7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one

Formula: C₁₅H₁₆O₃

Purity: 98%

Molecular weight: 244.29

Ref: IN-DG7596

Osthole

CAS: 484-12-8

Osthole (Osthol), a potential inhibitor of histamine H1 receptor, has been shown to stimulate osteoblast proliferation and differentiation.

Formula: C₁₅H₁₆O₃

Purity: 99.93% - 99.96%

Color and Shape: Fine White Powder

Molecular weight: 244.2857

Ref: TM-T2848

Osthole

CAS: 484-12-8

Formula: C₁₅H₁₆O₃

Molecular weight: 244.29

Ref: 4Z-C-1628

Osthole

CAS: 484-12-8

Lactone

Formula: C₁₅H₁₆O₃

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 244.29

Ref: 5G-89747

Osthole

CAS: 484-12-8

Osthole is a coumarin derivative, which is a type of natural compound. It is predominantly sourced from the Cnidium monnieri plant, as well as other Apiaceae family members. Osthole exerts its effects primarily through modulation of various molecular pathways, including the suppression of inflammatory mediators and the modulation of calcium channels, which results in vasodilation and various other physiological effects.

Formula: C₁₅H₁₆O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 244.29 g/mol

Ref: 3D-FO09975

Osthole

CAS: 484-12-8

Formula: C₁₅H₁₆O₃

Molecular weight: 244.28

Ref: BE-RMT17300

Osthole

CAS: 484-12-8

Formula: C₁₅H₁₆O₃

Molecular weight: 244.28

Ref: BE-RMCC372020

7-Methoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one

CAS: 484-12-8

Formula: C₁₅H₁₆O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 244.29

Ref: 10-F077928