CAS 486-35-1
:Daphnetin
Description:
Daphnetin, with the CAS number 486-35-1, is a naturally occurring coumarin derivative primarily extracted from the bark of the Daphne genus, particularly Daphne mezereum. It is characterized by its white crystalline appearance and has a molecular formula of C10H8O4. Daphnetin exhibits a range of biological activities, including anti-inflammatory, antioxidant, and antimicrobial properties, making it of interest in pharmacological research. The compound is soluble in organic solvents such as ethanol and dimethyl sulfoxide, but has limited solubility in water. Daphnetin's structure features a hydroxyl group and a methoxy group, contributing to its reactivity and potential interactions with various biological targets. Additionally, it has been studied for its potential therapeutic applications, including its role in modulating signaling pathways related to inflammation and cancer. As with many natural compounds, further research is necessary to fully elucidate its mechanisms of action and potential clinical uses.
Formula:C9H6O4
InChI:InChI=1/C9H6O4/c10-6-3-1-5-2-4-7(11)13-9(5)8(6)12/h1-4,10,12H
InChI key:InChIKey=ATEFPOUAMCWAQS-UHFFFAOYSA-N
SMILES:OC1=C2C(=CC=C1O)C=CC(=O)O2
Synonyms:- 2H-1-Benzopyran-2-one, 7,8-dihydroxy-
- 2H-1-benzopyran-2-one, 4,8-dihydroxy-
- 4,8-Dihydroxy-2H-chromen-2-one
- 7,8-Dihydroxy-2H-1-benzopyran-2-one
- 7,8-Dihydroxycoumarin
- 7,8-dihydroxy-2H-benzopyran-2-one
- 7,8-dihydroxy-2H-chromen-2-one
- Coumarin, 7,8-dihydroxy-
- Daphnetol
- NSC 633563
- Ruixiangsu
- Daphnetin
- Daphenetin
- Daphnetin，7,8-Dihydroxycoumarin
- DAPHNETIN(P)
- AKOS 213-37
- 7,8-dihydroxy-coumari
- 7,8-DIHYDROXY-CHROMEN-2-ONE
- 7,8-dihydroxy-2h-1-benzopyran-2-on
- 7,8-DIHYDROXYCOUMARIN (DAPHNETIN)
- See more synonyms
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Found 13 products.
Daphnetin
CAS:Daphnetin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.Formula:C9H6O4Purity:(HPLC) ≥95%Color and Shape:PowderMolecular weight:178.152H-1-Benzopyran-2-one, 7,8-dihydroxy-
CAS:Formula:C9H6O4Purity:95%Color and Shape:SolidMolecular weight:178.14157,8-Dihydroxycoumarin (Daphnetin)
CAS:Formula:C9H6O4Purity:(HPLC) ≥ 90.0%Color and Shape:Off-white to light yellow or pink powderMolecular weight:178.14Daphnetin
CAS:Formula:C9H6O4Purity:>90.0%(HPLC)Color and Shape:White to Light yellow to Light red powder to crystalMolecular weight:178.14Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14Daphnetin
CAS:LactoneFormula:C9H6O4Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:178.147,8-Dihydroxycoumarin
CAS:<p>7,8-Dihydroxycoumarin is a naturally occurring coumarin, which is derived from plants and certain fungi. It possesses a distinct chemical structure characterized by a benzopyrone core with hydroxyl groups at the 7th and 8th positions, contributing to its distinct biochemical properties. The mode of action of 7,8-Dihydroxycoumarin is largely attributed to its ability to act as a potent antioxidant, scavenging free radicals and chelating metal ions, thus mitigating oxidative stress at the cellular level.</p>Formula:C9H6O4Purity:Min. 95%Color and Shape:PowderMolecular weight:178.14 g/mol7,8-Dihydroxycoumarin, tech grade - 40%
CAS:<p>7,8-Dihydroxycoumarin (7,8-DHC) is a natural compound that has been shown to inhibit the expression of the P-glycoprotein (Pgp) gene and protein. 7,8-DHC binds to the response element in the Pgp gene promoter and inhibits transcriptional activity. This inhibition of transcription prevents the production of new Pgp proteins, which leads to an increase in drug resistance. 7,8-DHC also has been shown to bind to bcl-2 protein in vitro and prevent its release from mitochondria. This prevents apoptosis by inhibiting mitochondrial membrane permeability. Coumarin derivatives have been shown as potential therapeutic agents for bowel diseases such as ulcerative colitis and Crohn's disease. Daphnetin, a coumarin derivative found in dandelion roots, has shown promise as a treatment for colitis in mice models.</p>Formula:C9H6O4Purity:(%) Min. 40%Color and Shape:PowderMolecular weight:178.14 g/mol
