CAS 486-35-1
:Daphnetin
Description:
Daphnetin, with the CAS number 486-35-1, is a naturally occurring coumarin derivative primarily extracted from the bark of the Daphne genus, particularly Daphne mezereum. It is characterized by its white crystalline appearance and has a molecular formula of C10H8O4. Daphnetin exhibits a range of biological activities, including anti-inflammatory, antioxidant, and antimicrobial properties, making it of interest in pharmacological research. The compound is soluble in organic solvents such as ethanol and dimethyl sulfoxide, but has limited solubility in water. Daphnetin's structure features a hydroxyl group and a methoxy group, contributing to its reactivity and potential interactions with various biological targets. Additionally, it has been studied for its potential therapeutic applications, including its role in modulating signaling pathways related to inflammation and cancer. As with many natural compounds, further research is necessary to fully elucidate its mechanisms of action and potential clinical uses.
Formula:C9H6O4
InChI:InChI=1/C9H6O4/c10-6-3-1-5-2-4-7(11)13-9(5)8(6)12/h1-4,10,12H
InChI key:InChIKey=ATEFPOUAMCWAQS-UHFFFAOYSA-N
SMILES:OC1=C2C(=CC=C1O)C=CC(=O)O2
Synonyms:- 2H-1-Benzopyran-2-one, 7,8-dihydroxy-
- 2H-1-benzopyran-2-one, 4,8-dihydroxy-
- 4,8-Dihydroxy-2H-chromen-2-one
- 7,8-Dihydroxy-2H-1-benzopyran-2-one
- 7,8-Dihydroxycoumarin
- 7,8-dihydroxy-2H-benzopyran-2-one
- 7,8-dihydroxy-2H-chromen-2-one
- Coumarin, 7,8-dihydroxy-
- Daphnetol
- NSC 633563
- Ruixiangsu
- Daphnetin
- Daphenetin
- Daphnetin，7,8-Dihydroxycoumarin
- DAPHNETIN(P)
- AKOS 213-37
- 7,8-dihydroxy-coumari
- 7,8-DIHYDROXY-CHROMEN-2-ONE
- 7,8-dihydroxy-2h-1-benzopyran-2-on
- 7,8-DIHYDROXYCOUMARIN (DAPHNETIN)
- See more synonyms
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Daphnetin
CAS:Formula:C9H6O4Purity:>90.0%(HPLC)Color and Shape:White to Light yellow to Light red powder to crystalMolecular weight:178.147,8-Dihydroxycoumarin
CAS:7,8-DihydroxycoumarinFormula:C9H6O4Purity:98%Color and Shape:SolidMolecular weight:178.141547,8-Dihydroxycoumarin (Daphnetin)
CAS:Formula:C9H6O4Purity:(HPLC) ≥ 90.0%Color and Shape:Off-white to light yellow or pink powderMolecular weight:178.14Daphnetin (Standard)
CAS:Daphnetin (Standard) is a reference standard for research and analysis in studies involving Daphnetin. Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-inflammatory activities.Formula:C9H6O4Molecular weight:178.1415Daphnetin
CAS:Daphnetin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.Formula:C9H6O4Purity:(HPLC) ≥95%Color and Shape:PowderMolecular weight:178.15Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formula:C9H6O4Purity:97.47% - 99.95%Color and Shape:SolidMolecular weight:178.1415Daphnetin
CAS:LactoneFormula:C9H6O4Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:178.147,8-Dihydroxycoumarin
CAS:7,8-Dihydroxycoumarin is a naturally occurring coumarin, which is derived from plants and certain fungi. It possesses a distinct chemical structure characterized by a benzopyrone core with hydroxyl groups at the 7th and 8th positions, contributing to its distinct biochemical properties. The mode of action of 7,8-Dihydroxycoumarin is largely attributed to its ability to act as a potent antioxidant, scavenging free radicals and chelating metal ions, thus mitigating oxidative stress at the cellular level.Formula:C9H6O4Purity:Min. 95%Color and Shape:PowderMolecular weight:178.14 g/mol
