CAS 487-41-2

Phillyrin

Description:

Phillyrin, with the CAS number 487-41-2, is a chemical compound primarily derived from the plant species *Forsythia suspensa*, commonly known for its traditional medicinal uses. It is classified as a phenolic glycoside, which means it consists of a phenolic compound linked to a sugar moiety. Phillyrin exhibits various biological activities, including antioxidant, anti-inflammatory, and potential antiviral properties, making it of interest in pharmacological research. The compound is typically characterized by its solubility in organic solvents and limited solubility in water, which is common for many phenolic compounds. Its structure includes a phenolic ring, contributing to its reactivity and interaction with biological systems. In terms of safety, like many natural compounds, it is essential to consider its dosage and potential side effects when used in therapeutic contexts. Overall, phillyrin represents a significant area of study in natural product chemistry and its applications in health and medicine.

Formula: C₂₇H₃₄O₁₁

InChI: InChI=1/C27H34O11/c1-32-17-6-4-13(8-19(17)33-2)25-15-11-36-26(16(15)12-35-25)14-5-7-18(20(9-14)34-3)37-27-24(31)23(30)22(29)21(10-28)38-27/h4-9,15-16,21-31H,10-12H2,1-3H3/t15-,16-,21+,22+,23-,24+,25?,26+,27+/m0/s1

InChI key: InChIKey=KFFCKOBAHMGTMW-LGQRSHAYSA-N

SMILES: O(C)C=1C=C([C@@H]2[C@@]3([C@@]([C@@H](OC3)C4=CC(OC)=C(OC)C=C4)(CO2)[H])[H])C=CC1O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O

Synonyms:

• 1H,3H-Furo[3,4-c]furan, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• 4-(4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo(3,4-c)furan-1-yl)-2-methoxyphenyl, (1S-(1alpha,3aalpha,4beta,6aalpha))-beta-D-glucopyranoside
• 4-[(1S,3aR,4R,6aR)-4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl β-<span class="text-smallcaps">D</span>-glucopyranoside
• 4-[(1S,3aR,4R,6aR)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl beta-D-glucopyranoside
• 4-[(1S,3aR,4R,6aR)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl β-D-glucopyranoside
• Forsythin
• Phillygenin β-<span class="text-smallcaps">D</span>-glucopyranoside
• Phillygenin-O-Beta-D-Glucopyranoside
• Phillyroside
• Phyllyrin
• beta-D-Glucopyranoside, 4-(4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo(3,4-c)furan-1-yl)-2-methoxyphenyl, (1S-(1alpha,3aalpha,4beta,6aalpha))-
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, 4-[(1S,3aR,4R,6aR)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, 4-[4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl, [1S-(1α,3aα,4β,6aα)]-
• β-D-Glucopyranoside, 4-[4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl, [1S-(1α,3aα,4β,6aα)]-
• 1H,3H-Furo[3,4-c]furan, β-D-glucopyranoside deriv.
• β-D-Glucopyranoside, 4-[(1S,3aR,4R,6aR)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl
• Phillyrin
• FORSYTHIN 98%
• Pillyrin
• FORSYTHIN PHILLYRIN
• dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl
• Chionanthin
• PHEOPHYTHIN A (SH)
• β-D-Glucopyranoside,4-[(1S,3aR,4R,6aR)-4-(3,4-

Phillyrin

CAS: 487-41-2

Formula: C₂₇H₃₄O₁₁

Purity: >95.0%(HPLC)

Molecular weight: 534.56

Ref: 3B-P3053

Forsythin

CAS: 487-41-2

Formula: C₂₇H₃₄O₁₁

Purity: 95%

Color and Shape: Solid

Molecular weight: 534.5523

Ref: IN-DA00DECK

Phillyrin

CAS: 487-41-2

Phillyrin

Formula: C₂₇H₃₄O₁₁

Purity: ≥98%

Molecular weight: 534.55

Ref: 54-BUP10578

Phillyrin

CAS: 487-41-2

Ref: 7W-GC3963

Forsythin

CAS: 487-41-2

Forsythin

Formula: C₂₇H₃₄O₁₁

Purity: 95%

Molecular weight: 534.55

Ref: 54-OR1025881

Phillyrin (Standard)

CAS: 487-41-2

Phillyrin (Standard) is a reference standard for research and analysis in studies involving Phillyrin. Phillyrin (Forsythin) is a novel AMPK activator, has anti-obesity effects in nutritive obesity mice, it can prevent lipid accumulation in HepG2 cells by blocking the expression of SREBP-1c and FAS through LKB1/AMPK activation. Phillyrin(Forsythin) may be a new preventive agent of acute lung injury in the clinical setting, it potentially contributes to the suppression of the activation of MAPK and NF-κB pathways, it also has protective effects on H2O2-induced oxidative stress and apoptosis in PC12 cells.

Formula: C₂₇H₃₄O₁₁

Molecular weight: 534.5523

Ref: TM-TMSM-2434

Phillyrin

CAS: 487-41-2

Formula: C₂₇H₃₄O₁₁

Purity: 95%~99%

Molecular weight: 534.558

Ref: BP-BP1087

Phillyrin

CAS: 487-41-2

Applications: Phillyrin is a natural lignan compound attenuating tumor necrosis factor secreted from macrophages, that play an inportant role in adipocyte dysfunctions. Anti-obesity.
References Kong, P. et al.: Planta. Med., 80, 880 (2014);

Formula: C₂₇H₃₄O₁₁

Color and Shape: Neat

Molecular weight: 534.55

Ref: TR-P338400

Phillyrin

CAS: 487-41-2

Phillyrin (Forsythin) is a novel AMPK activator, has anti-obesity effects in nutritive obesity mice, it can prevent lipid accumulation in HepG2 cells.

Formula: C₂₇H₃₄O₁₁

Purity: 98.28% - 99.71%

Color and Shape: Solid

Molecular weight: 534.5523

Ref: TM-T2854

Phillyrin

CAS: 487-41-2

Natural glycoside

Formula: C₂₇H₃₄O₁₁

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 534.56

Ref: 5G-89532

Phillyrin

CAS: 487-41-2

Phillyrin is a lignan compound, which is a bioactive chemical derived from the seeds and fruits of the plant Forsythia suspensa, a traditional medicinal herb. This compound is recognized for its multifaceted mode of action, primarily through its anti-inflammatory, antioxidant, and antimicrobial properties. Phillyrin functions by modulating signaling pathways, inhibiting oxidative stress, and suppressing pro-inflammatory cytokine production, making it significant in the field of pharmacology.

Formula: C₂₇H₃₄O₁₁

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 534.55 g/mol

Ref: 3D-MP08141

Forsythin

CAS: 487-41-2

Formula: C₂₇H₃₄O₁₁

Molecular weight: 534.6

Ref: BE-RMT13000

Phillyrin

CAS: 487-41-2

(2S,3R,4S,5S,6R)-2-(4-((1S,3aR,4R,6aR)-4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl)-3-methoxyphenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Formula: C₂₇H₃₄O₁₁

Purity: 95%

Molecular weight: 534.55

Ref: IN-DG299811