CAS 487021-52-3: 1-(4-Methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea

Description: 1-(4-Methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea is a chemical compound characterized by its unique structural features, which include a urea functional group, a methoxybenzyl moiety, and a nitro-substituted thiazole ring. This compound typically exhibits moderate to high solubility in organic solvents, while its solubility in water may vary depending on pH and temperature. The presence of the nitro group suggests potential for biological activity, often associated with antimicrobial or anticancer properties. The thiazole ring contributes to the compound's reactivity and may influence its interaction with biological targets. Additionally, the methoxy group can enhance lipophilicity, potentially affecting the compound's pharmacokinetics. Overall, this compound's characteristics make it of interest in medicinal chemistry and drug development, particularly in the search for novel therapeutic agents. As with any chemical substance, safety and handling precautions should be observed, given the potential toxicity associated with nitro and thiazole-containing compounds.

Formula: C₁₂H₁₂N₄O₄S

InChI: InChI=1/C12H12N4O4S/c1-20-9-4-2-8(3-5-9)6-13-11(17)15-12-14-7-10(21-12)16(18)19/h2-5,7H,6H2,1H3,(H2,13,14,15,17)

Synonyms:

• N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea
• Urea, N-[(4-methoxyphenyl)methyl]-N'-(5-nitro-2-thiazolyl)-
• Ar-A014418

AR-A014418

CAS: 487021-52-3

• Formula: C₁₂H₁₂N₄O₄S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 308.3131

AR-A014418

CAS: 487021-52-3

• Purity: 99.93%
• Molecular weight: 308.31g/mol

AR-A014418

CAS: 487021-52-3

• Formula: C₁₂H₁₂N₄O₄S
• Molecular weight: 308.31

AR-A014418

CAS: 487021-52-3

AR-A014418 (GSK 3β inhibitor VIII) is an ATP-competitive, and selective GSK3β inhibitor.

• Formula: C₁₂H₁₂N₄O₄S
• Purity: 99.94% - ≥95%
• Color and Shape: Solid
• Molecular weight: 308.31

AR-AO 14418

CAS: 487021-52-3

Applications AR-AO 14418 is a glycogen synthase kinase 3β (GSK-3β) inhibitor (1,2,3). GSK-3β is a …

• Formula: C₁₂H₁₂N₄O₄S
• Color and Shape: Neat
• Molecular weight: 308.31

AR-AO 14418

CAS: 487021-52-3

Inhibitor of GSK3β kinase

• Formula: C₁₂H₁₂N₄O₄S
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 308.31 g/mol